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This study investigated the role of the antimicrobial peptide cathelicidin in Escherichia coli O157:H7 infection and subsequent renal damage. Mouse and human cathelicidin, CRAMP and LL-37, respectively, killed E. coli O157:H7 in vitro. Intestines from healthy wild-type (129/SvJ) and cathelicidin-knock-out (Camp(-/-)) mice were investigated, showing that cathelicidin-deficient mice had a thinner co

The inverse of the standard estimate of covariance matrix is frequently used in the portfolio theory to estimate the optimal portfolio weights. For this problem, the distribution of the linear transformation of the inverse is needed. We obtain this distribution in the case when the sample size is smaller than the dimension, the underlying covariance matrix is singular, and the vectors of returns a

We demonstrate interstitial diffuse optical time-of-fight spectroscopy based on a single fiber for both light delivery and detection. Detector saturation due to the massive short-time reflection is avoided by ultrafast gating of a single photon avalanche diode. We show that the effects of scattering and absorption are separable and that absorption can be assessed independently of scattering. Measu

This article analyses the professionalization of the education field in Sweden from a historical perspective by tracing efforts towards professionalization of teaching from a clerically consecrated to a scientifically grounded praxis. Some of these efforts seem to be fairly typical for welfare states like Sweden. However, others are more unique, such as the state ambition to create a unified teach

Syftet med denna studie är att studera hur äldre personer ser på cykeln och vilka möjligheter cykeln ger, vad som får en äldre person att sluta cykla och vilken påverkan det får samt hur olycksbilden och hjälmanvändningen ser ut bland äldre personer. Tre delstudier genomfördes, en kvantitativ enkätundersökning bland personer som är 65 år och äldre, fokusgruppsintervjuer med äldre cyklister och ana

Abstract is not available

The leading cause of work related accidents in Sweden is falls. Many slips and falls occur on icy and snowy surfaces, but there is limited knowledge about how to prevent accidents during outdoor work in winter conditions. The purpose of this study was to describe risk factors of slips and falls and criteria for slip-resistant winter shoes from a user perspective. The result is based on focus group

In general churches talk a lot about the importance of education. At the same time their educational praxis is often fragmentized. The most crucial factor for this is a weak connection between the Church's identity and its activity. When this link is diffuse, different activities have a tendency to live their own lives. This article examines some basic official Church documents from half a dozen c

beta-Alanine synthase (PAS) is the third enzyme in the reductive pyrimidine catabolic pathway, which is responsible for the breakdown of the nucleotide bases uracil and thymine in higher organisms. It catalyzes the hydrolysis of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyrate to the corresponding beta-amino acids. beta ASs are grouped into two phylogenetically unrelated subfamilies, a

This report describes the development of an ultrasound based self localization system for mobile robots. The robot navigates using a combination of internal wheel encoders and absolute distance information from a sensor network. The sensor fusion problem is formulated as a non-linear state estimation problem which is approximated using an extended Kalman filter.

Where conservation resources are limited and conservation targets are diverse, robust yet flexible priority-setting frameworks are vital. Priority-setting is especially important for geographically widespread species with distinct populations subject to multiple threats that operate on different spatial and temporal scales. Marine turtles are widely distributed and exhibit intra-specific variation

The aim of the present study was to investigate whether virulent CagA positive Helicobacter pylori strains are those preferentially related to abdominal aortic aneurysm (AAA) rupture. Several microorganisms have been linked to aneurysm development. Chronic Chlamydophila pneumoniae infection has been suggested as a possible contributing factor for the development and expansion of AAA. Previous stud

Attention is drawn to the feasibility of using high sensitivity isothermal heat conduction calorimetry to study metabolic responses of differently processed and stored fresh-cut fruit. The heat production of endogenous (tissue metabolism during 12 h of analysis at 10 degrees C for kiwifruit and strawberry) and exogenous (microbial growth during 18 d of analysis at 10 degrees C for cantaloupe) biol

Vernacular buildings in Egypt express a variety of passive low-tech approaches in design and construction to achieve human comfort and fulfil inhabitants’ requirements. They have been devised to suit living in regions where local inhabitants had to invent various passive building strategies to live under severe local climatic conditions without depending on fossil fuels. This paper discusses a ret

The existence of infinite periodic lipid bilayer structures in biological systems was first demonstrated in cell membrane assemblies. Such periodicity is only possible in symmetric bilayers, and their occurrence is discussed here in relation to the asymmetry of cell membranes in vivo. A periodic membrane conformation in the prolamellar body of plants corresponds to a dormant state without photosyn

A primary functionality of context aware applications is the retrieval of different types of context data from various context sources and adapting their behavior accordingly. In order to facilitate context aware application development, a context aware middleware must provide an effective context data management and lookup strategy. The use of a traditional index for indexing dynamic context data