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INTRODUCTION: Monocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated. However, very little is known about how they contribute to disease and attain their pathological features. Therefore, we set out to investigate the functional alterations of synovial monocytes in childhood-onset arthritis,

Background Human trafficking is considered a hidden global crime with unsubstantiated numbers. Despite the challenges in counting or measuring this crime, reports revealed the presence of around 40.3 million victims worldwide. Human trafficking results in severe detrimental impacts on both mental and physical health. Given the sensitivity and negative consequences of human trafficking on the globa

En bok om "det modernas sociala innebörd", om trendskiften och nya attityder gällande allt från förnamn och badrumsinredningar till mat, pedagogik och terapi.

Selection leading to adaptation to interactions may generate rapid evolutionary feedbacks and drive diversification of species interactions. The challenge is to understand how the many traits of interacting species combine to shape local adaptation in ways directly or indirectly resulting in diversification. We used the well-studied interactions between Lithophragma plants (Saxifragaceae) and Grey

PURPOSE: While patients with intermediate-risk (IR) Wilms tumors now have an overall survival (OS) rate of almost 90%, those affected by high-stage tumors with diffuse anaplasia have an OS of only around 50%. We here identify key events in the pathogenesis of diffuse anaplasia by mapping cancer cell evolution over anatomic space in Wilms tumors.EXPERIMENTAL DESIGN: We spatially mapped subclonal la

The boreal landscape stores an estimated 40% of the earth's carbon (C) found in terrestrial vegetation and soils, with a large portion collected in thick organic soil layers. These ground stores are subject to substantial removals due to the centurial return of wildfire, which has strong impacts on the soil microbial community and nutrient cycling, which in turn can control ecosystem recovery patt

The extent to which newly developed blood-based biomarkers could reduce screening costs in secondary prevention trials of Alzheimer's disease is mostly unexplored. We collected plasma amyloid-β42/40, apolipoprotein E ϵ4 status and amyloid PET at baseline in 181 cognitively unimpaired participants [the age of 72.9 (5.3) years; 61.9% female; education of 11.9 (3.4) years] from the Swedish BioFINDER-

How does violent conflict affect the spread of Covid-19? In this paper we analyze how violent conflict influences the adoption of preventative measures and infection rate in a very poor, conflict-affected country, Burkina Faso. We use a unique panel of 1,919 households surveyed during the first six months of the Covid-19 pandemic in 2020 and merge these data with indicators of violence at the muniHow does violent conflict affect the spread of Covid-19? In this paper we analyze how violent conflict influences the adoption of preventative measures and infection rate in a very poor, conflict-affected country, Burkina Faso. We use a unique panel of 1,919 households surveyed during the first six months of the Covid-19 pandemic in 2020 and merge these data with indicators of violence at the muni

Pollen plays a key role in plant reproductive biology. Despite the long history of research on pollen and pollination, recent advances in pollen-tracking methods and statistical approaches to linking plant phenotype, pollination performance, and reproductive fitness yield a steady flow of exciting new insights. In this introduction to the Special Issue “Pollen as the Link Between Phenotype and Fit

Purpose: This article explores how public librarians understand and perform the democratic mission of public libraries in times of political and social turbulence, and critically discusses the idea of public libraries as meeting places.Methodology: Five group interviews conducted with public librarians in southern Sweden are analyzed using a typology of four perspectives on democracy.Findings: TwoPurposeThis article explores how public librarians understand and perform the democratic mission of public libraries in times of political and social turbulence and critically discusses the idea of public libraries as meeting places.Design/methodology/approachFive group interviews conducted with public librarians in southern Sweden are analyzed using a typology of four perspectives on democracy.Fi