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Toward a standard approach to measurement and reporting of perioperative mortality rate as a global indicator for surgery.

The proportion of patients who die during or after surgery, otherwise known as the perioperative mortality rate (POMR), is a credible indicator of the safety and quality of operative care. Its accuracy and usefulness as a metric, however, particularly one that enables valid comparisons over time or between jurisdictions, has been limited by lack of a standardized approach to measurement and calcul

Multiple paths of development: knowledge bases and institutional characteristics of the Swedish food sector

The aim of this paper is to explore the relation between the critical knowledge base of firms and how firms respond to incentives embedded in the institutional framework surrounding them. The analysis gives us a better understanding of the complex development of the food sector in Southern Sweden in the past decades. Theoretically, the paper combines concepts of path dependency and knowledge bases

Interrater reliability and construct validity of the Posture and Postural Ability Scale in adults with cerebral palsy in supine, prone, sitting and standing positions.

Objective:To evaluate reliability, internal consistency and construct validity of the Posture and Postural Ability Scale for adults with cerebral palsy.Design:Psychometric evaluation of a clinical assessment tool.Setting:Rehabilitation centres in Sweden and Iceland.Subjects:Thirty adults with cerebral palsy aged 19-22 years, six people at each level I-V of the Gross Motor Function Classification S

Production of 3-hydroxypropionic acid from 3-hydroxypropionaldehyde by recombinant Escherichia coli co-expressing Lactobacillus reuteri propanediol utilization enzymes.

3-Hydroxypropionic acid (3-HP) is an important platform chemical for the biobased chemical industry. Lactobacillus reuteri produces 3-HP from glycerol via 3-hydroxypropionaldehyde (3-HPA) through a CoA-dependent propanediol utilization (Pdu) pathway. This study was performed to verify and evaluate the pathway comprising propionaldehyde dehydrogenase (PduP), phosphotransacylase (PduL), and propiona

Reliability and validity of the assessment of neurological soft-signs in children with and without attention-deficit-hyperactivity disorder

AIM To study the value and reliability of an examination of neurological soft-signs, often used in Sweden, in the assessment of children with attentiondeficit– hyperactivity disorder (ADHD), by examining children with and without ADHD, as diagnosed by an experienced clinician using the DSM-III-R. METHOD We have examined interrater reliability (26males, nine females; age range 5y 6mo–11y), internal

Simplicity of partial skew group rings with applications to Leavitt path algebras and topological dynamics

Let A be a commutative and associative ring (not necessarily unital), G a group and α a partial action of G on ideals of A, all of which have local units. We show that A is maximal commutative in the partial skew group ring A*G if and only if A has the ideal intersection property in A*G. From this we derive a criterion for simplicity of A*G in terms of maximal commutativity and G-simplicity of A.

Geochronology and geochemical evidence for a magmatic arc setting for the Ni-Cu mineralised 1.79Ga Kleva gabbro-diorite intrusive complex, southeast Sweden

Magmatic Ni-Cu sulphide deposits are commonly associated with mafic rocks within the marginal areas of Archean or Proterozoic cratons. The Kleva Ni-Cu sulphide deposit in southeast Sweden is hosted by gabbro-diorite rocks and is sandwiched between two Palaeoproterozoic magmatic arcs: the Transscandinavian Igneous Belt (TIB) and the Oskarshamn-Jonkoping Belt (OJB). Major and trace element data corr

Gastroenteritis and the novel picornaviruses aichi virus, cosavirus, saffold virus, and salivirus in young children

Background: During the last few years many new human picornaviruses have been discovered due to advances in metagenomics and other molecular biological approaches. The clinical significance and the occurrence are only sparsely described. Objectives: To determine the epidemiology and clinical significance of infections with the novel human picornaviruses, aichi virus, cosavirus, salivirus, and saff

Homozygous factor V Leiden and double heterozygosity for factor V Leiden and prothrombin mutation.

The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well as patients with double heterozygosity for FVL and PTM. All patients with homozygous FVL, PTM or double

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene varian

The contradictory role of the sales assistant: superordination and subordination

Abstract: The social relationship between sales assistants and customers has often been described as relatively one-sided one in which sales assistants are subordinate to customers. One of the ways in which the subordination of sales assistants is manifested is when customers treat them badly, for instance in the form of verbal and physical abuse. We suggest that these power relations are not one-

A Process Concept for High-Purity Production of Amines by Transaminase-Catalyzed Asymmetric Synthesis: Combining Enzyme Cascade and Membrane-Assisted ISPR

For the amine transaminase (ATA)-catalyzed synthesis of chiral amines, the choice of donor substrate is of high importance for reaction and process design. Alanine was investigated as an amine donor for the reductive amination of a poorly water-soluble ketone (4-phenyl-2-butanone) in a combined in situ product removal (ISPR) approach using liquid-membrane extraction together with an enzyme cascade

An interglacial polar bear and an early Weichselian glaciation at Poolepynten, western Svalbard

The recent discovery of a subfossil polar bear (Ursus maritimus) jawbone in the Poolepynten coastal cliff sequence, western Svalbard, and its implications for the natural history of the polar bear motivated an effort to better constrain the environmental history and age envelope of the Poolepynten sediment sequence. The focus of the present study is on the lithostratigraphy of the coastal cliffs a

Study of carrier concentration in single InP nanowires by luminescence and Hall measurements

The free electron carrier concentrations in single InP core-shell nanowires are determined by micro-photoluminescence, cathodoluminescence (CL) and Hall effect measurements. The results from luminescence measurements were obtained by solving the Fermi-Dirac integral, as well as by analyzing the peak full width at half maximum (FWHM). Furthermore, the platform used for Hall effect measurements, com

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.

Increased age, BMI and HbA1c levels are risk factors for several non-communicable diseases. However, the impact of these factors on the genome-wide DNA methylation pattern in human adipose tissue remains unknown. We analyzed DNA methylation of ∼480,000 sites in human adipose tissue from 96 males and 94 females, and related methylation to age, BMI and HbA1c. We also compared epigenetic signatures i

Mass transport of contaminated soil released into surface water by landslides (Göta River, SW Sweden)

Landslides of contaminated soil into surface water represent an overlooked exposure pathway that has not been addressed properly in existing risk analysis for landslide hazard, contaminated land, or river basin management. A landslide of contaminated soil into surface water implies an instantaneous exposure of the water to the soil, dramatically changing the prerequisites for the mobilisation and

Box Jellyfish Use Terrestrial Visual Cues for Navigation

Box jellyfish have an impressive set of 24 eyes of four different types, including eyes structurally similar to those of vertebrates and cephalopods [1, 2]. However, the known visual responses are restricted to simple phototaxis, shadow responses, and object avoidance responses [3-8], and it has been a puzzle why they need such a complex set of eyes. Here we report that medusae of the box jellyfis

Contact system activation in severe infectious diseases.

Hemostasis is a sensitive and tightly regulated process, involving vascular endothelium and blood cells, as well as factors of the coagulation and fibrinolytic cascades. In severe and invasive infectious diseases, the equilibrium between the procoagulant and anticoagulant status of the host may change dramatically and can induce life-threatening complications. A growing body of evidence suggests t