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Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive – they produce not only antibodies against foreign substances, but also against the body’s own substances, and it is unclear why the immune system allows for the devel

https://www.stemcellcenter.lu.se/article/how-self-reactive-immune-cells-are-allowed-develop - 2025-11-08

By Pia [dot] romare [at] fsi [dot] lu [dot] se (Pia Romare) - published on 23 August 2018“We must understand the ageing process itself in order to help people with conditions such as Alzheimer’s and dementia, and to possibly enable us to prevent these diseases from arising”, says Henrik Ahlenius of the Stem Cell Centre at Lund University. His aim is to develop an experimental model for human nerve

https://www.stemcellcenter.lu.se/article/how-do-dementia-diseases-affect-our-brains - 2025-11-08

Zaal Kokaia, Professor within the Department of Clinical Sciences and Director of Lund Stem Cell Center, has been awarded Georgia’s most prestigious scientific prize - the National Prize in Science.  The award comes as a result of his outstanding contribution to world class scientific research and was presented to Prof. Kokaia at a ceremony in the Presidential Palace, Tbilisi, by the Georgian Pres

https://www.stemcellcenter.lu.se/article/prestigious-scientific-prize-awarded-director-lund-stem-cell-center - 2025-11-08

Margarita Chumarina, from the iPSC laboratory for CNS disease modeling, will be defending her PhD thesis on Wednesday 15th of January. Researching in the group led by Laurent Roybon, Margarita has been utilizing stem cell-based models to study cellular alterations in Parkinson’s disease. Here, Margarita answers a few questions about her research and time spent at Lund Stem Cell Center. What have y

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-margarita-chumarina - 2025-11-08

Sara Nolbrant, from the Developmental and Regenerative Neurobiology lab, will be defending her PhD thesis on Friday 31st of January. Researching in the group led by Malin Parmar, Sara has been directing and dissecting the fate of dopaminergic neurons with the aim developing cell replacement therapy for the treatment of Parkinson’s disease. Here, Sara answers a few questions about her research and

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-sara-nolbrant - 2025-11-08

We are very happy to announce that two new PIs have joined Lund Stem Cell Center! Björn Nilsson is Professor of Clinical Immunology at the Medical Faculty of Lund University, and the Head of the Division of Hematology and Transfusion Medicine at the Department of Laboratory Medicine. He is also a visiting researcher at the Broad Institute (Cambridge, MA) and now a member of Lund Stem Cell Center.T

https://www.stemcellcenter.lu.se/article/two-new-principal-investigators-lund-stem-cell-center - 2025-11-08

Diabetes, cardiovascular disease, Parkinson's and Alzheimer's disease make up the world’s most common diseases. A new biobank at Lund University in Sweden - the largest of its kind - with stem cells from both those affected and healthy individuals, will contribute to an increased understanding of how these diseases arise. “The goal is for researchers to be able to develop new treatments that can p

https://www.stemcellcenter.lu.se/article/worlds-largest-stem-cell-biobank-launched-0 - 2025-11-08

High school students from all over the Skåne region will be visiting Lund University to spend a whole day discussing the current state of stem cell research, discovering what it is like to work in a research setting, and exploring the exciting future possibilities that stem cells have to offer. Building on the success of the previous five years, Lund Stem Cell Center is hosting UniStem Day March 6

https://www.stemcellcenter.lu.se/article/continued-interest-stem-cells-among-high-school-students - 2025-11-08

Wallenberg Molecular Medicine Fellow Agnete Kirkeby has re-established her research group at Lund Stem Cell Center. With labs situated at both Lund and at the Department of Neuroscience at Copenhagen University, Agnete’s aim is to develop stem cell-based neural cell therapies to replace lost neurons as a treatment for brain diseases. As a main project, the Kirkeby research groups focus is on the d

https://www.stemcellcenter.lu.se/article/pi-agnete-kirkeby-returns-lund-stem-cell-center - 2025-11-08

Lund Stem Cell Center employees and students are hereby invited to enter the Image Competition 2020! We want inspirational images that capture the spirit of Lund Stem Cell Center. Any research related images will be accepted. Not just pictures of cells or sections, it could be your work environment, equipment, imaging, laboratory researchers, it’s up to you! We want to showcase the amazing researc

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-image-competition-2020 - 2025-11-08

UniStem Day 2020 was another great success, with high school students visiting Lund University to enjoy a variety of activities introducing them to the fascinating world of stem cell research. The 6th UniStem day hosted by Lund University kicked off at the LUX Aula lecture theatre, Lund University, where over 200 high school students from over the Skåne region were welcomed by event co-ordinator A

https://www.stemcellcenter.lu.se/article/bringing-stem-cell-research-next-generation-scientists - 2025-11-08

Researchers from Lund University have now succeeded in restoring mobility and sensation in rats that have suffered Stroke, by transplanting neurons developed from reprogrammed human skin cells into animal brains. “Six months after transplant, we could see how the new cells had repaired the damage that a stroke had caused in the brains of rats," explains Professor Zaal Kokaia, who together with sen

https://www.stemcellcenter.lu.se/article/scientists-repair-stroke-damaged-rat-brain-1 - 2025-11-08

With a research focus on the development and application of in vitro models to study human brain evolution and disease, PhD student Daniela Grassi will be defending her thesis on Thursday 23rd of April 2020. Here, Daniela tells us about her research in the Molecular Neurogenetics group, led by Johan Jakobsson, and her time spent at Lund Stem Cell Center. Can you tell us about your research?During

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-daniela-grassi - 2025-11-08

Carla Azevedo is set to defend her PhD thesis titled “Oligodendroglial (dys)function in alpha-synucleinopathies” on Thursday 30th of April. Here, Carla answers a few questions about her PhD journey at Lund Stem Cell Center, researching in the iPSC Laboratory for CNS disease modeling. How did you end up doing a PhD at Lund Stem Cell Center?I’m originally from Porto, Portugal. After my undergraduate

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-carla-azevedo - 2025-11-08

Huntington disease is fatal inherited brain disorder, usually emerging during mid-life. Although there is currently no known cure, the Molecular Neurogenetics group at Lund Stem Cell Center aims to understand the defective cellular processes leading to the progression of this disease. Characterised by symptoms including impaired motor and cognitive function, Huntington disease is caused by the exp

https://www.stemcellcenter.lu.se/article/autophagy-and-treatment-huntington-disease-timing-key - 2025-11-08

Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be able to produce different types of neural cells for the treatment of neurologica

https://www.stemcellcenter.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-11-08

Neurogenesis, the process by which new neurons are formed, dramatically declines in the aging brain. A research group from Lund Stem Cell Center have published a study that sheds light on the different factors contributing to this loss, particularly the role of inflammation. “One of the focuses of our research is on what goes wrong in the brain during aging” explains Henrik Ahlenius, principle inv

https://www.stemcellcenter.lu.se/article/researchers-identify-novel-regulator-neurogenesis-aged-brain - 2025-11-08

PhD student Franziska Olm has been developing a microfluidic-based acoustophoresis method to process stem cell preparations label-free, a technique with great research and clinical potential. In this interview, Franziska tells us about her PhD project, her time at Lund Stem Cell Center and her plans following her thesis defence on Friday June 12th 2020. Can you tell us about your research?Complex

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-franziska-olm - 2025-11-08

Researchers from Lund Stem Cell Center have identified a novel target for the expansion of human blood stem cells ex vivo and shed light on the mechanism of action of a stem cell promoting molecule, currently in phase II clinical trials. Hematopoietic stem cell transplantation is a curative therapy for many patients suffering from life threatening blood disorders. This treatment is currently limit

https://www.stemcellcenter.lu.se/article/new-insights-ex-vivo-expansion-transplantable-human-blood-stem-cells - 2025-11-08

The Centre for Advanced Middle Eastern Studies supports research projects with high scientific potential through the Strategic Research Area (SRA): Middle East in the Contemporary World (MECW).  The Centre for Advanced Middle Eastern Studies (CMES) supports writing retreats on Middle East research with the aim to finalise an article, book chapter, edited volume or a book for publication in peer re

https://www.cmes.lu.se/article/call-cmes-writing-retreat - 2025-11-08