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The right to water has been recently recognized as a fundamental human right by the United Nations, thereby clarifying its status as ‘legally binding’, making it ‘justiciable’ and enforceable. This development has been heralded as a key that holds great potential to change the lives of the billions who still lack access to clean water. Many of those deprived of enjoyment of the right are children,
In the present investigation, we sought to refine the classification of urothelial carcinoma by combining information on gene expression, genomic, and gene mutation levels. For these purposes, we performed gene expression analysis of 144 carcinomas, and whole genome array-CGH analysis and mutation analyses of FGFR3, PIK3CA, KRAS, HRAS, NRAS, TP53, CDKN2A, and TSC1 in 103 of these cases. Hierarchic
De utsatta bostadsområdena har under årens lopp varit föremål för ett varierande tvärvetenskapligt intresse med inriktning allt ifrån arkitektur, byggteknik och allmänna kommunikationer, till samhällsvetenskapliga studier av bostadspolitikens effekter: befolkningssammansättningar, demokrati, segregation, osv. Forskningsfältet är således i sig mångfasetterat och kan sägas spegla olika perspektiv på
Nucleoside analogues (NA) are prodrugs that are phosphorylated by deoxyribonucleoside kinases (dNKs) as the first step towards a compound toxic to the cell. During the last 20 years, research around dNKs has gone into new organisms other than mammals and viruses. Newly discovered dNKs have been tested as enzymes for suicide gene therapy. The tomato thymidine kinase 1 (ToTK1) is a dNK that has been
Objectives. To evaluate the agreement and performance of two tests for aPLs with regard to association with manifestations of the APS in patients with SLE.Methods. We investigated 712 SLE patients and 280 population controls. Cardiolipin and β(2) glycoprotein-I antibodies were measured with routine ELISA and a new automated method. Three positivity cut-offs (99%, 90% of controls and recommended cu
Objective. An extensive remodeling of the human cervical connective tissue occurs throughout pregnancy, with a decrease in the total concentration of collagen and proteoglycans. We hypothesized that the profound changes in proteoglycan production in the cervix would be seen in corresponding cervical fibroblasts as well. Methods. Cervical biopsies were obtained from five non-pregnant women, five wo
Heart period variability and heart rate were studied in 15 women and 15 men while they were viewing negatively (snakes/spiders), neutrally (scenic views), and positively (cats and kittens/puppies and dogs) valenced films. Time-frequency analyses of the heart period variability power spectrum in the high frequency region (0.12-0.4 Hz), reflecting respiratory sinus arrhythmia (RSA), were carried out
The printing of a manuscript of lectures in medieval archaeology by docent Rikard Holmberg: Kyrkobyggnad, kult and samhälle. Landskyrkan i Lunds forna ärkestift genom tiderna (Church building, cult and society. The country church in the former arch bishopric of Lund through time) from 1972-73
Kulturartikel om science fiction-författaren Arthur C Clarke med anledning av den aktuella romanen 3001 - The Final Odyssey.
