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Fossil fuel companies’ existence is incompatible with the planet’s survival, says Bill McKibben Paris 2015 will be one step along the line, not the thing that solves all the problemsWe now have solutions we didn’t have 25 years ago, we should deploy them with all possible speed

BACKGROUND: Arsenic exposure affects [Formula: see text] people worldwide, including [Formula: see text] in Bangladesh. Arsenic exposure increases the risk of cancer and other chronic diseases, and one potential mechanism of arsenic toxicity is epigenetic dysregulation. OBJECTIVE: We assessed associations between arsenic exposure and genome-wide DNA methylation measured at baseline among 396 Bangl

Argon, krypton, xenon, carbon, nitrogen, sulfur, and phosphorus have all been measured and found to be enriched by a quasi uniform factor in the 2-4 range, compared to their protosolar values, in the atmosphere of Jupiter. To elucidate the origin of these volatile enrichments, we investigate the possibility of an inward drift of particles made of amorphous ice and adsorbed volatiles, and their abi

This paper introduces a special issue of The History of the Family on sanitation and urban mortality. The special issue contains papers which focus on the impact of sanitary reforms on mortality change in Australia, Switzerland, Finland, Sweden, and England and Wales. The current paper outlines the main features of the debate over the causes of mortality change and the role played by sanitary refo

The globular clusters of large spiral galaxies can be divided into two populations: one that formed in situ and one that comprises clusters tidally stripped away from other galaxies. In this paper, we investigate the contribution to the outer globular cluster population in the M31 galaxy through donation of clusters from dwarf galaxies. We test this numerically by comparing the contribution of glo

Objectives: Gastrointestinal symptoms are common in endometriosis, but the mechanisms behind these symptoms are yet poorly understood. Associations between endometriosis and irritable bowel syndrome (IBS), celiac disease, and various autoimmune diseases have been reported. These diseases express characteristic autoantibodies. The aim of the current study was to investigate autoantibodies against g

This pilot study is an attempt to explore how fundamental frequency (f0) as an acoustic correlate to paralinguistic infor- mation and biological codes are em- ployed in interspecific vocal communi- cation. Measures of f0 in human (Homo sapiens) and domestic cat (Felis catus) intra- and interspecific communication were compared. Results showed higher mean f0 in interspecific than intraspe- cific ut

Frontotemporal dementia (FTD)-causing mutations in the CHMP2B gene lead to the generation of mutant C-terminally truncated CHMP2B. We report that transgenic mice expressing endogenous levels of mutant CHMP2B developed late-onset brain volume loss associated with frank neuronal loss and FTD-like changes in social behaviour. These data are the first to show neurodegeneration in mice expressing mutan

BACKGROUND: No practical tool quantitates the risk of circulatory-etiology death (CED) immediately after successful cardiopulmonary resuscitation in patients without ST-segment-elevation myocardial infarction. We developed and validated a prediction model to rapidly determine that risk and facilitate triage to individualized treatment pathways. METHODS: With the use of INTCAR (International Cardia