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Foraminiferal and δ13C isotopic event-stratigraphy across the Danian–Selandian transition at Zumaya (northern Spain): chronostratigraphic implications

The Zumaya section, northern Spain, is a suitable candidate to define the Global Stratotype Section and Point for the base of the Selandian Stage (Palaeocene) because of its excellent accessibility, exposure and stratigraphic continuity. Uncertainties exist, however, with regard to the stratigraphic horizon where to place the Danian/Selandian (D/S) boundary. Five potential stratigraphic horizons (

Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells.

The majority of human embryonic stem cell lines depend on a feeder cell layer for continuous growth in vitro, so that they can remain in an undifferentiated state. Limited knowledge is available concerning the molecular mechanisms that underlie the capacity of feeder cells to support both the proliferation and pluripotency of these cells. Importantly, feeder cells generally lose their capacity to

Long-term desmopressin response in primary nocturnal enuresis: open-label, multinational study

Primary nocturnal enuresis (PNE) is a distressing condition, particularly in severe cases (>= 3 wet nights/week). A prevalent pathophysiological mechanism, especially in monosymptomatic PNE (PMNE), is commonly believed to be an insufficient increase in night-time release of antidiuretic hormone. Desmopressin, a synthetic analogue of antidiuretic hormone, has been shown to reduce the number of wet

Microemulsion Phase Behavior of Aerosol-OT Combined with a Cationic Hydrotrope in the Dilute Region

The phase behavior of systems containing minimum amounts of sodium bis (2-ethylhexyl) sulfosuccinate with equimolar ratio of tetra ethyl ammonium chloride were studied as a function of salt concentration and alkane carbon number at ambient temperature. Visual inspection as well as cross polarizers were used to detect anisotropy. Solubilization ratios for oil and brine in the middle phases were mea

Recombinant Factor C (rFC) Assay and Gas Chromatography/Mass Spectrometry (GC/MS) Analysis of Endotoxin Variability in Four Agricultural Dusts

Endotoxin exposure is a significant concern in agricultural environments due to relatively high exposure levels. The goals of this study were to determine patterns of 3-hydroxy fatty acid (3-OHFA) distribution in dusts from four types of agricultural environments (dairy, cattle feedlot, grain elevator, and corn farm) and to evaluate correlations between the results of gas chromatography/mass spect

Functional Magnetic Resonance Imaging in Prostate Cancer

Context: Magnetic resonance imaging (MRI) combined with magnetic resonance spectroscopy imaging (MRSI), dynamic contrast-enhanced MRI, and diffusion-weighted MRI emerged as promising tests in the diagnosis of prostate cancer, and they show encouraging results. Objective: This review emphasizes different functional MRI techniques in the diagnosis of prostate cancer and includes information about th

Hot Jupiters and Cool Stars

Close-in planets are in jeopardy, as their host stars evolve off the main sequence (MS) to the subgiant and red giant phases. In this paper, we explore the influences of the stellar mass (in the range 1.5-2M similar to), mass-loss prescription, planet mass (from Neptune up to 10 Jupiter masses), and eccentricity on the orbital evolution of planets as their parent stars evolve to become subgiants a

Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide-1 on beta-cell secretion and insulin clearance in mice

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) potently augment insulin response to glucose. It is less known what their effects are insulin clearance, which also contributes to peripheral hyperinsulinemia observed after administration of incretins together with glucose. The aims of this study were the quantification of C-peptide secretion and the evaluation

Modification by the genes ALAD and VDR of lead-induced cognitive effects in children

Lead has negative effect on cognitive functions in children. However, individuals differ in susceptibility. One possible explanation is a genetic predisposition. Polymorphisms in the B-aminolevulinic acid dehydratase (ALAD) and the vitamin D receptor (VDR) genes may modify lead metabolism and neurotoxicity, but information regarding the central nervous system is very limited. The aim of the study

The R&D-growth paradox arises in fast-growing sectors

Several notions of a R&D paradox can be found in the literature. In the Swedish Paradox version, the emphasis is normally on high and growing levels of business R&D connected to comparatively low GDP growth rates. This paper examines whether this pattern is consistent over time and, more importantly, which sectors drive the aggregate patterns. Based on an investigation of the entire Swedis

Low-level occupational 14C contamination – results from a pilot study

This paper presents a pilot study in which specific activities of (14)C in hair and urine from 11 radiation workers handling (14)C-containing substances have been measured using accelerator mass spectrometry. Varying degrees of contamination were revealed: up to 63% excess in hair and 400% excess in urine. Although the (14)C excess reported in this study would result in low effective doses, it wou

ICELANDIC NURSING HOME RESIDENTS: THEIR MORTALITY, HEALTH, FUNCTIONAL PROFILE, AND CARE QUALITY, USING THE MINIMUM DATA SET OVER TIME

Popular Abstract in Icelandic SUMMARY IN ICELANDIC Samantekt á íslensku Hlutfall eldra fólks í Evrópu sem og annars staðar í heiminum hefur aukist og þá sérstaklega þeirra sem eru 80 ára og eldri. Vegna hrumleika og langvinnra sjúkdóma er líklegt að þessi aldurshópur þarfnist aðstoðar frá hinu opinbera, m. a. vistunar á hjúkrunarheimilum. Því má ætla að á komandi árum muni hjúkrunarheimilin standThe overall aim of this thesis was to investigate trends over time in residents’ health status, functional profile and predictors of mortality at admission to Icelandic nursing homes and in addition to determine upper and lower thresholds for Minimum Data Set (MDS) Quality Indicators, to investigate the prevalence of quality indicators over time and their association with the health status and fun

Mind the gap, Inequalities in infant and child mortality: the case of Colombia, 1967-2010

The aim of this dissertation is to examine how differences in socioeconomic status, race and place of residence interact with infant and child mortality in Colombia over the period 1967-2010. One of the reasons why the study focuses on infant and child mortality is that the living conditions of children are outside their control, and therefore a good measure of inequality of opportunity. This stud

Decoupling of behavioural and morphological differentiation in a partially migratory bird population

Capsule Resident Blackcaps in eastern Spain differ in morphology and isotope profile from central European conspecifics wintering in the area, but not from locally breeding migrants. Aims Natural selection shapes flight morphology in relation to migratory habits. Thus, intraspecific variation in migratory behaviour is often paralleled by morphological differentiation. We test whether differences i

Reaction of [Ru-3(CO)(12)] with tri(2-furyl)phosphine: Di- and tri-substituted triruthenium and phosphido-bridged diruthenium complexes

Reaction of [Ru-3(CO)(12)] with tri(2-furyl)phosphine, P(C4H3O)(3), at 40 degrees C in the presence of a catalytic amount of Na[Ph2CO] furnishes two triruthenium complexes [Ru-3(CO)(10){P(C4H3O)(3)}(2)] (1) and [Ru-3(CO)(9){P(C4H3O)(3)}(3)] (2) with the ligand coordinated through the phosphorus atom. Treatment of 1 and 2 with Me3NO at 40 degrees C affords the dinuclear phosphido-bridged complexes

Genes involved in muscle contractility and nutrient signaling pathways within celiac disease risk loci show differential mRNA expression

Background: Risk gene variants for celiac disease, identified in genome-wide linkage and association studies, might influence molecular pathways important for disease development. The aim was to examine expression levels of potential risk genes close to these variants in the small intestine and peripheral blood and also to test if the non-coding variants affect nearby gene expression levels in chi