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Simulation is an important tool within epidemiology for both learning and developing new methodology. Unfortunately, few epidemiology training programs teach basic simulation methods. Read the paper at https://academic.oup.com/aje/article/190/8/1696/6140874
https://www.lupop.lu.se/article/simulation-practice-balancing-intercept - 2025-09-29
The benefits of using data from national registers as endpoints in epidemiological studies must be weighed against the impact of potentially decreased data quality. Read the paper at https://journals.sagepub.com/doi/full/10.1177/14034948211021191
Unmeasured confounding is a common threat to the validity of observational studies. In practice, confounding bias may arise from both confounders that are completely unmeasured and from confounders that are measured with error. Read the paper at https://academic.oup.com/ije/article/50/3/711/6048186
https://www.lupop.lu.se/article/cautionary-note-recently-proposed-sensitivity-analysis-unmeasured-confounding - 2025-09-29
We explored the comparability of anxiety measures from register- and survey-based data including analyses of prevalence and associations with selected psychiatric and somatic diseases. Read the paper at https://onlinelibrary.wiley.com/doi/full/10.1111/acps.13339
https://www.lupop.lu.se/article/use-register-and-survey-based-measures-anxiety-population-based-danish-cohort - 2025-09-29
Immeasurable time bias exaggerates drug benefits in pharmacoepidemiological studies due to exposure misclassification arising from the inability to measure in-hospital medications in many health care databases. Read the paper at https://academic.oup.com/ije/article/50/3/987/6048410
https://www.lupop.lu.se/article/analytical-approaches-minimizing-immeasurable-time-bias-cohort-studies - 2025-09-29
Interrupted time-series (ITS) designs are a robust and increasingly popular non-randomized study design for strong causal inference in the evaluation of public health interventions. Read the paper at https://academic.oup.com/ije/article/50/3/1011/5937253
We report the current status of CKD registries in Europe in relation to their data collection on patients not on KRT so that in the future we may investigate to what extent also their data may be used for similar purposes, like collaborative research on CKD trajectories and patient outcomes. Read the paper at https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfab252/63…
The aim of this study was to explore the potential misclassification and evaluate the completeness of esophageal cancer diagnoses in the FCR and HILMO, considering misclassification. Read the paper at https://www.tandfonline.com/doi/full/10.1080/0284186X.2020.1792547
The term of overadjustment bias is used to refer to different scenarios. Here, we propose a unified definition of overadjustment, with four types. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/Revisiting_Overadju…
https://www.lupop.lu.se/article/revisiting-overadjustment-bias - 2025-09-29
General population-based cohort studies provide solid evidence on mass Helicobacter pylori (HP) eradication effects. Self-reported questionnaires are occasionally used in such studies to ascertain the HP eradication history. However, reports on the reliability of these questionnaires are lacking. Read the paper at https://www.nature.com/articles/s41598-021-95124-1
Forskningsrådet Formas lanserar en ny satsning på forskning för en giftfri miljö, specifikt till projekt som kan öka kunskapen kring kombinationseffekter av kemikalier och substanser. Läs mer här.
https://www.lupop.lu.se/article/giftfri-miljo-i-fokus-ny-forskningssatsning - 2025-09-29
A cardiovascular mortality algorithm applied to administrative health records had moderate validity when compared to vital statistics data. Substantial variation existed across study sites representing different geographic locations and two healthcare systems. These variations may reflect different diagnostic coding practices and healthcare utilization patterns. Read the paper at https://bmchealth
This commentary provides a practical perspective on epidemiological analysis within a single high-dimensional study of moderate size to consider a causal question. Read the paper at https://academic.oup.com/ije/article/50/3/1016/6140018
The value of accurate healthcare data has never been more apparent than during the past year, and there is increasing recognition of the important role surgical registries play in driving improved patient outcomes, patient safety, and academic research. Successful registries need to be responsive and adapt to the rapidly changing clinical environment. Read the paper at https://academic.oup.com/bjs
https://www.lupop.lu.se/article/future-surgical-registries - 2025-09-29
Molecular pathological epidemiology research provides information about pathogenic mechanisms. A common study goal is to evaluate whether the effects of risk factors on disease incidence vary between different disease subtypes. Read the paper at https://academic.oup.com/ije/article/50/3/1030/6114706
New research at Lund University shows that the biological parents’ genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease. Previous research by diabetes researcher Rashmi Prasad has shown
https://www.ludc.lu.se/article/new-study-parents-metabolic-traits-can-affect-childs-health-over-time - 2025-09-29
The results of an observational study from Lund University in Sweden are clear: up to the age of two, a more fibre-rich diet seems to reduce the risk of coeliac disease. A particularly clear link was seen when children had eaten fibre-rich foods before the age of one. “This is the first time the risk of coeliac disease has been studied based on fibre in children’s diets. But a clinical trial is al
Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation provides support to two diabetes researchers at Lund University Diabetes Centre who contribute with new knowledge to this research field. Type 1 diabetes is a condition wh
https://www.ludc.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-09-29
International researchers who study islets of Langerhans met for a conference in Malmö in June. Studies of insulin-producing cells help us understand disease mechanisms in diabetes. Lund University Diabetes Centre and the strategic research area EXODIAB hosted the event. Lund University Diabetes Centre (LUDC) and the strategic research are EXODIAB (Excellence of Diabetes Research in Sweden) hosted
https://www.ludc.lu.se/article/international-islet-cell-researchers-met-conference-malmo - 2025-09-29
Congratulations to Charlotte Ling who, together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. The funding will support clinical research in precision medicine, focusing on epigenetic analysis of blood samples from 13,000 individuals. Charlotte Ling, a professor in diabetes research with a particular focus on epigeneti
https://www.ludc.lu.se/article/charlotte-ling-receives-major-grant-clinical-diabetes-research - 2025-09-29
