Filtyp
The modern study of Wilms tumour was prompted nearly 50 years ago, when Alfred Knudson proposed the ‘two-hit’ model of tumour development. Since then, the efforts of researchers worldwide have substantially expanded our knowledge of Wilms tumour biology, including major advances in genetics — from cloning the first Wilms tumour gene to high-throughput studies that have revealed the genetic landsca
We present the results from our investigation of angular correlations between baryons pairs in the Pythia8 event generator. We show how colour reconnection models and hadronization mechanisms influence such angular correlations and in particular address the effect of gluons on the baryon production mechanism in the Lund string fragmentation model. We conclude by discussing the new theoretical idea
We study a stochastic model of consensus formation, introduced in 2015 by Grinfeld, Volkov and Wade, who called it a multidimensional randomized Keynesian beauty contest. The model was generalized by Kennerberg and Volkov, who called their generalization the Jante's law process. We consider a version of the model where the space of possible opinions is a convex body B in Rd. N individuals in a pop
Background: Women are disproportionately affected by migraine, representing up to 75% of all migraine cases. This discrepancy has been proposed to be influenced by differences in hormone levels between the sexes. One such hormone is progesterone. Calcitonin gene-related peptide (CGRP) system is an important factor in migraine pathophysiology and could be influenced by circulating hormones. The pur
Artikeln bygger på en utvärdering som gjordes 2021-2022 när den brottspreventiva metoden SafeGrowth testades i området Drottninghög. Artikel utgår från ett polisperspektiv och visar på möjligheter med metoden, men också svårigheten att implementera en metod utvecklad i en specifik kontext, i andra miljöer.
Due to restrictions following the Covid-19 pandemic,major changes regarding teaching have been called for. Sincestudents’ presence in lab classrooms has been very restricted alsophysical labs have had to be transformed into e.g. simulationsperformed at home or via remote connections. After lifting of therestrictions, hybrid learning where both physical and simulatedlab environment are combined havDue to restrictions following the Covid-19 pandemic,major changes regarding teaching have been called for. Sincestudents’ presence in lab classrooms has been very restricted alsophysical labs have had to be transformed into e.g. simulationsperformed at home or via remote connections. After lifting of therestrictions, hybrid learning where both physical and simulatedlab environment are combined hav
This chapter addresses the ways in which the complexity of global governance enables or constrains political agency. An increasingly complex global institutional system—with its growing level of unpredictability and uncertainties—challenges some of the classical institutionalist tenets in respect of conditions of power and agency. For instance, the capacities of central governance institutions and
Background: It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of UPFs with the risk of multimorbidity defined as the co-occurrence of at least two chronic diseases in an individual among first cancer at any site, cardiovascular disease, and type 2 diabetes.
IL-1, plays a role in some pathological inflammatory conditions. This pro-inflammatory cytokine also has a crucial role in tumorigenesis and immune responses in the tumor microenvironment (TME). IL-1 receptor accessory protein (IL-1RAP), combined with IL-1 receptor-1, provides a functional complex for binding and signaling. In addition to the direct role of IL-1, some studies demonstrated that IL1
Most research on the neurostructural basis of language abilities in children stems from small samples and surface-based measures. To complement and expand the existent knowledge, we investigated associations between grey matter volume and language performance in a large sample of 9-to-11-year-old children, using data from the Adolescent Brain Cognitive Development (ABCD) Study (N = 1865) and an al
Recently impressive weight loss has been reported for novel incretin therapies based on dual-and triple-hormone receptor coagonists. These agents have potential as being positioned as early therapeutics for metabolic diseases for which weight loss is preferred, such as type 2 diabetes, obesity, cardiovascular diseases, and nonalcoholic liver disease. This development will change the landscape of f
Natural and human-induced environmental changes deeply affected terrestrial ecosystems throughout the Holocene. Paleoenvironmental reconstructions provide information about the past and allow us to predict/model future scenarios. Among potential records, peat bogs are widely used because they present a precise stratigraphy and act as natural archives of highly diverse organic remains. Over the dec
Background: In January 2010, the choice reform was instituted in Swedish primary health care establishing free entry for private primary health care providers and enabling patients to choose freely among primary health care centers. The motivation behind the reform was to improve access to primary care and responsiveness to patient expectations. Reform effects on health care utilization have previ
Ultra-f aint dw arf galaxies (UFDs) are commonly found in close proximity to the Milky Way and other massive spiral galaxies. As such, their projected stellar ellipticity and extended light distributions are often thought to owe to tidal forces. In this paper, we study the projected stellar ellipticities and faint stellar outskirts of tidally isolated ultra-faints drawn from the 'Engineering Dwarf
The course Global Environmental Governance Today–Actors, Institutions, Complexity is an in- terdisciplinary PhD course and has welcomed participants from a wide range of disciplinary backgrounds with equally varied prior knowledge on environmental governance practices and theories. Thus, every year, participants include students who are not familiar with international relations theories such as re
Background: Previous studies demonstrated increases in diagnostic confidence and change in patient management after amyloid-PET. However, studies investigating longitudinal outcomes over an extended period of time are limited. Therefore, we aimed to investigate clinical outcomes up to 9 years after amyloid-PET to support the clinical validity of the imaging technique. Methods: We analyzed longitud
