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Sexual dimorphism in immune function changes during the annual cycle in house sparrows

Difference between sexes in parasitism is a common phenomenon among birds, which may be related to differences between males and females in their investment into immune functions or as a consequence of differential exposure to parasites. Because life-history strategies change sex specifically during the annual cycle, immunological responses of the host aiming to reduce the impact of parasites may

A model of the decision-making process during pre-evacuation

The behaviour of building occupants before the purposive movement towards an exit, known as the pre-evacuation behaviour, can have a strong impact on the total time required to leave a building in case of fire emergency as well as on the number of casualties and deaths. The pre-evacuation time can be simulated within computational models using different approaches. This work introduces a new model

Decision-Analytic Models: Current Methodological Challenges

Modelers seeking to help inform decisions about insurance (public or private) coverage of the cost of pharmaceuticals or other health care interventions face various methodological challenges. In this review, which is not meant to be comprehensive, we cover those that in our experience are most vexing. The biggest challenge is getting decision makers to trust the model. This is a major problem bec

Cyclic Nucleotide Phosphodiesterase 3 Signaling Complexes

The superfamily of cyclic nucleotide phosphodiesterases is comprised of 11 gene families. By hydrolyzing cAMP and cGMP, PDEs are major determinants in the regulation of intracellular concentrations of cyclic nucleotides and cyclic nucleotide-dependent signaling pathways. Two PDE3 subfamilies, PDE3A and PDE3B, have been described. PDE3A and PDE3B hydrolyze cAMP and cGMP with high affinity in a mutu

Growing interest in use of geographic information systems in health and healthcare research: a review of PubMed from 2003 to 2011.

Abstract in Undetermined There has been an increasing interest in applying GIS into health and healthcare research in recent years.4,5 However, this increasing interest has not yet been gauged. In order to address this, the current study was performed to examine the crude number and the annual rate of papers with ‘Geographic Information Systems’ among their MeSH Terms in PubMed (a free database wh

System size and beam energy dependence of azimuthal anisotropy from PHENIX

We present azimuthal anisotropy measurements in Au+Au and Cu+Cu collisions at and 200 GeV. Comparison between reaction plane and cumulant v2 measurements in Au+Au collisions at GeV shows that non-flow contributions, originating mainly from jets, influence the extracted v2 for pT 3.5 GeV/c. Number of constituent quark (NCQ) scaling of v2, when studied as a function of transverse kinetic energy KET,

Imaging of gynecological disease (2): clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli-Leydig cell tumors and Leydig cell tumors

Objective To describe the clinical history and ultrasound findings in women with ovarian Sertoli cell, Sertoli-Leydig cell and Leydig cell tumors. Methods Women with a histological diagnosis of Sertoli cell tumor, Sertoli-Leydig cell tumor or Leydig cell tumor who bad undergone preoperative ultrasound examination were identified from the databases of each of three participating ultrasound centers.

Diffusion NMR for Determining the Homogeneous Length-Scale in Lamellar Phases.

The size of the anisotropic domains in a lyotropic liquid crystal is estimated using a new protocol for diffusion NMR. Echo attenuation decays are recorded for different durations of the displacement-encoding gradient pulses, while keeping the effective diffusion time and the range of the wave vectors constant. Deviations between the sets of data appear if there are non-Gaussian diffusion processe

Apolipoprotein M – Studies of Structure and Function

Apolipoprotein M (apoM), a 25 kDa plasma protein, is found in all major lipoprotein classes, although the majority is found in high density lipoproteins (HDL). ApoM has been suggested to be involved in the formation of and adding to the antiatherogenic functions of HDL, but its function is still not completely known. ApoM has been suggested to be a lipokalin. By studies in vitro using recombinant

Evolutionary responses of communities to extinctions

Question: What are the evolutionary consequences of extinctions in ecological communities? Can evolution restore pre-extinction communities by replacing lost ecological strategies with similar ones, or will communities change in fundamental ways and never be the same again? Mathematical approach: We develop and explore a new framework based on evolutionary domains of attraction (EDAs), defined as