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Purpose: Hematoma volume is the strongest predictor of patient outcome after intracerebral hemorrhage (ICH). The aim of this study was to validate novel fully automated software for quantification of ICH volume on non-contrast computed tomography (CT). Methods: The population was defined from the Swedish Stroke Register (RS) and included all patients with an ICH diagnosis during 2016–2019 in Regio

I denna artikel används två kartläggningar av samma rättsliga begrepp, nämligen praktiska verkställighetshinder i utlänningslagen, för att illustrera olika sätt att närma sig migrationsrätten som studieobjekt. Artikeln beskriver, vidareutvecklar och argumenterar för en reflexiv kritisk rättskartografisk metod i kvalitativa studier av svensk migrationsrätt. Med avstamp i Boaventura de Sousa Santos

Background: Self-reported sex problems among women diagnosed with reproductive and nonreproductive cancers before the age of 40 are not fully understood. This study aimed to determine sexual dysfunction in young women following a cancer diagnosis in relation to women of the general population. Furthermore, to identify factors associated with sexual dysfunction in women diagnosed with cancer. Mater

There is a great need for techniques which enable reproducible separation of extracellular vesicles (EVs) from biofluids with high recovery, purity and throughput. The development of new techniques for isolation of EVs from minute sample volumes is instrumental in enabling EV-based biomarker profiling in large biobank cohorts and paves the way to improved diagnostic profiles in precision medicine.

There is growing evidence that the environment experienced by one generation can influence phenotypes in the next generation via transgenerational plasticity (TGP). One of the best-studied examples of TGP in animals is predator-induced transgenerational plasticity, whereby exposing parents to predation risk triggers changes in offspring phenotypes. Yet, there is a lack of general consensus synthes

Experimental and cross-linguistic studies have shown that vocal iconicity is prevalent in words that carry meanings related to size and shape. Although these studies demonstrate the importance of vocal iconicity and reveal the cognitive biases underpinning it, there is less work demonstrating how these biases lead to the evolution of a sound symbolic lexicon in the first place. In this study, we s

TRPV2 is a ligand-operated temperature sensor with poorly defined pharmacology. Here, we combine calcium imaging and patch-clamp electrophysiology with cryo-electron microscopy (cryo-EM) to explore how TRPV2 activity is modulated by the phytocannabinoid Δ9-tetrahydrocannabiorcol (C16) and by probenecid. C16 and probenecid act in concert to stimulate TRPV2 responses including histamine release from

The urban cemetery is a built green environment that is both a place of death, belonging to the bereaved and their rituals of care and remembrance, and a recreational space, where people rest, walk their dog, jog, reflect in silence, or just pass through. Urban cemeteries and urban parks share some features and uses in that respect, but they also have very different meanings and functions. The resThe urban cemetery is a built green environment that is both a place of death, belonging to the bereaved and their rituals of care and remembrance, and a recreational space, where people rest, walk their dog, jog, reflect in silence, or just pass through. Urban cemeteries and urban parks share some features and uses in that respect, but they also have very different meanings and functions. The res

The article presents a legal ethnographic study of the contradiction between the rhetoric of return, stressing that rejected asylum seekers should leave the country, and the reality of legally stranded migrants, in a Swedish context. Through an in-depth analysis of three individual asylum case files, the study reveals how a situation comes about where rejected asylum seekers end up as legally stra

Heterostructured nanowires exhibit unique physical and electronic properties and are most commonly grown by the vapor-liquid-solid mechanism. Some of these properties are related to the interfacial abruptness of the heterointerface which makes its understanding and control particularly important for further development. In this regard, we present a model based on mass balance of atoms in the catal

Timely diagnosis of Alzheimer's disease (AD) is critical for appropriate treatment/patient management. Cerebrospinal fluid (CSF) biomarker analysis is often used to aid diagnosis. We assessed analytical performance of second-generation (Gen II) Elecsys® CSF immunoassays (Roche Diagnostics International Ltd), and adjusted existing cut-offs, to evaluate their potential utility in clinical routine. A

Patient-derived cells hold great promise for precision medicine approaches in human health. Human dermal fibroblasts have been a major source of cells for reprogramming and differentiating into specific cell types for disease modeling. Postmortem human dura mater has been suggested as a primary source of fibroblasts for in vitro modeling of neurodegenerative diseases. Although fibroblast-like cell

BACKGROUND: Alzheimer's disease is characterized by an abnormal increase of phosphorylated tau (pTau) species in the CSF. It has been suggested that emergence of different pTau forms may parallel disease progression. Therefore, targeting multiple specific pTau forms may allow for a deeper understanding of disease evolution and underlying pathophysiology. Current immunoassays measure pTau epitopes

With "la Vie de Saint Louis", dated 1309, Jean de Joinville left to posterity a hybrid text that defies definitive classification. His “I” is the very first in French literature and, for historians, the interest of his account lies in his description of the Seventh Crusade.The aim of this Master thesis 1 is to consider, from the perspective of historical writing, Joinville’s contributions and to d

The nature of blame is not to be identified solely with a judgment, or an overt act, or an angry emotion. Instead, blame should be identified with a sentiment: more specifically, a multi-track disposition that manifests itself in various different emotions, thoughts or actions in a range of different circumstances. This paper aims to argue for these two claims. I start by arguing that blame is not

This study explored the impact of question wording on attitudes toward trading sexual services. There are no previous research agendas investigating how views on the trade in sex are susceptible to question word choice. We utilized an original survey to assess how three different concepts used to represent the exchange of sexual services impact on the reported level of acceptability among responde