Mantle cell lymphoma (MCL) is an incurable disease with a highly variable clinical course. The prognosis after relapse is generally poor, and no standard of care exists. We investigated the postrelapse outcomes of 149 patients who were initially treated in the Nordic Lymphoma Group trials, MCL2 or MCL3, both representing intensive cytarabine-containing frontline regimens including autologous stem

Purpose: The COVID-19 pandemic brought unprecedented conditions for overall health care systems by restricting resources for non-COVID-19 patients. As the burden of the disease escalates, routine elective surgeries are being cancelled. The aim of this paper was to provide a guideline for management of endocrine surgical disorders during a pandemic. Methods: We used Delphi method with a nine-scale

Experimental methods to study the breakup frequency in industrial devices are increasingly important. Since industrial production-scale devices are often inaccessible to single-drop experiments, breakup frequencies for these devices can only be studied with “global methods”; i.e., breakup frequency estimated from analyzing emulsification-experiment data. However, how much can be said about the

BACKGROUND: The "Managing Fatigue" (MF) programme can help people living with Multiple sclerosis (MS) manage fatigue in their everyday lives. The programme has been proven feasible with Swedish occupational therapists, but there is a lack of knowledge of how MS participants experience the programme, and what they learned from participating in the programme.AIM: To describe how Swedish MS participa

The raw material tier in companies’ supply chains can be a hotspot for sustainability issues like deforestation and resulting legal, reputational, financial and operational risks – yet companies’ supply chain management efforts as well as research on sustainable supply chain management still focus on direct suppliers due to poor upstream transparency. With technical progress, remote sensing and sa

Johan Anselmsson och Burak Tunca på Ekonomihögskolan vid Lunds universitet har i samarbete med undersökningsföretaget Norstat en vecka efter Amazons lansering i Sverige gjort en uppföljning av vad som hänt sedan en liknande mätning gjordes i september, men då i samband med att spekulationer om Amazons intåg i Sverige tog fart.

Denna artikel bygger på aktuell internationell forskning samt en webbaserad enkätundersökning i ett samarbete mellan Ekonomihögskolan vid Lunds universitet och intervjuföretaget Norstat.

The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene

Recent studies of beetle specimens deposited in collections have revealed five species new to the Swedish fauna to be hiding amongst their closely related species. In some cases, the species known to the Swedish fauna are widespread and considered common, making it easy to overlook the slight differences that separate them from the similar and less common species. Some of these species are restric

This article analyses the long-term development of social class differences in infant and child mortality in an area of southern Sweden, spanning from the early stages of the mortality transition at the beginning of the nineteenth century, to the late 1960s when both infant and child mortality had reached very low levels. Our findings show that infant and child mortality was fairly equal at the be

ObjectiveWe investigate the association between the geographic proximity of the grandparents on net marital fertility and maternal survival in Sweden, 1900–1910, within the framework of the cooperative-breeding-hypothesis.MethodsData were derived from Swedish full-count censuses (1880–1910) and the Swedish Death Index. Married couples were linked to their parental households. Poisson and logistic

A wide range of medical examinations are using analysis of images from different types of equipment. Using artificial intelligence, the assessments could be done automatically. This can have multiple benefits for the healthcare; reduce workload for medical doctors, decrease variations in diagnoses and cut waiting times for the patient as well as improve the performance. The aim of this thesis has

Background: The management of cancer-related pain relies on access to opioids. When regular opioids are not tolerated, or are insufficient, methadone is an affordable and effective analgesic. Aim: The aim of the project was to describe the pattern of use and clinical experience of methadone in pediatric cancer pain at a governmental cancer hospital in Hyderabad, one of the four Indian cancer cente

Technology and innovation are important in addressing complex problems in the agricultural sector in many developing communities. However, ways and mechanisms to integrate them in the agricultural sector are still a challenge due to the lack of clear pathways and trajectories. Value chains are seen as a strong policy instrument to increase profitability in the agricultural sector; there is also de

Objective: The progress of accelerated atherosclerosis in systemic lupus erythematosus (SLE) is incompletely understood. Circulating osteopontin (OPN) is increased in autoimmune conditions, e.g. SLE, and its serum concentration wasrecently reported to associate with subclinical atherosclerosis in SLE, as measured by carotid intima-media thickness.The aim of this study was to investigate whether OP

Whereas subcultures such as punk, metal, skate, goth and emo have all been the target of moral panics in the past, the conditions that sparked these moral panics have since become banal and normalized, in line with Stanley Cohen’s claim that moral panics per definition tend to be short-lived. The moral panic about subcultural graffiti in Sweden, however, has proved remarkably consistent. Drawing f