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Early 2016/17 vaccine effectiveness estimates against influenza A(H3N2): I-MOVE multicentre case control studies at primary care and hospital levels in Europe

We measured early 2016/17 season influenza vaccine effectiveness (IVE) against influenza A(H3N2) in Europe using multicentre case control studies at primary care and hospital levels. IVE at primary care level was 44.1%, 46.9% and 23.4% among 0–14, 15–64 and ≥ 65 year-olds, and 25.7% in the influenza vaccination target group. At hospital level, IVE was 2.5%, 7.9% and 2.4% among ≥ 65, 65–79 and ≥ 80

TESS's first planet : A super-Earth transiting the naked-eye star π Mensae

We report on the confirmation and mass determination of π Men c, the first transiting planet discovered by NASA's TESS space mission. π Men is a naked-eye (V = 5.65 mag), quiet G0 V star that was previously known to host a sub-stellar companion (π Men b) on a longperiod (Porb = 2091 days), eccentric (e = 0.64) orbit. Using TESS time-series photometry, combined with Gaia data, published UCLES at AA

Mass determination of the 1:3:5 near-resonant planets transiting GJ 9827 (K2-135)

Context. Multiplanet systems are excellent laboratories to test planet formation models as all planets are formed under the same initial conditions. In this context, systems transiting bright stars can play a key role, since planetary masses, radii, and bulk densities can be measured. Aims. GJ 9827 (K2-135) has recently been found to host a tightly packed system consisting of three transiting smal

Super-Earth of 8 M in a 2.2-day orbit around the K5V star K2-216

Context. Although thousands of exoplanets have been discovered to date, far fewer have been fully characterised, in particular super-Earths. The KESPRINT consortium identified K2-216 as a planetary candidate host star in the K2 space mission Campaign 8 field with a transiting super-Earth. The planet has recently been validated as well. Aims. Our aim was to confirm the detection and derive the main

K2-260 b : A hot Jupiter transiting an F star, and K2-261 b: A warm Saturn around a bright G star

We present the discovery and confirmation of two new transiting giant planets from the Kepler extended mission K2. K2-260 b is a hot Jupiter transiting a V = 12.7 F6V star in K2 Field 13, with a mass and radius of M = 1.39-0.06+0.05 M⊙ and R = 1.69 ± 0.03 R. The planet has an orbital period of P = 2.627 d, and a mass and radius of MP = 1.42-0.32+0.31 MJ and RP = 1.552-0.057+0.048 RJ. This is the f

44 Validated Planets from K2 Campaign 10

We present 44 validated planets from the 10th observing campaign of the NASA K2 mission, as well as high-resolution spectroscopy and speckle imaging follow-up observations. These 44 planets come from an initial set of 72 vetted candidates, which we subjected to a validation process incorporating pixel-level analyses, light curve analyses, observational constraints, and statistical false positive p

HD 89345 : A bright oscillating star hosting a transiting warm Saturn-sized planet observed by K2

We report the discovery and characterization of HD 89345b (K2-234b; EPIC 248777106b), a Saturn-sized planet orbiting a slightly evolved star. HD 89345 is a bright star (V = 9.3 mag) observed by the K2 mission with 1 min time sampling. It exhibits solar-like oscillations. We conducted asteroseismology to determine the parameters of the star, finding themass and radius to be 1.12-0.01+0.04 M⊙ and 1.

K2-141 b : A 5- M super-Earth transiting a K7 v star every 6.7 h

We report on the discovery of K2-141 b (EPIC 246393474 b), an ultra-short-period super-Earth on a 6.7 h orbit transiting an active K7 V star based on data from K2 campaign 12. We confirmed the planet's existence and measured its mass with a series of follow-up observations: seeing-limited Muscat imaging, NESSI high-resolution speckle observations, and FIES and HARPS high-precision radial-velocity

K2-139 b : A low-mass warm Jupiter on a 29-d orbit transiting an active K0 V star

We announce the discovery of K2-139 b (EPIC 218916923 b), a transiting warm-Jupiter (Teq = 547± 25 K) on a 29-d orbit around an active (logR' HK =-4.46±0.06) K0V star in K2 Campaign 7.We derive the system's parameters by combining the K2 photometry with groundbased follow-up observations. With a mass of 0.387 -0.033+0.075 MJ and radius of 0.808 -0.033+0.034 RJ, K2-139 b is one of the transiting wa

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Abstract in Thaiชาวจีนจำนวนมากเดินทางเข้ามายังเดลี-เมดานในช่วงศตวรรษที่ 19 ในฐานะแรงงานสัญญาจ้างเพื่อพัฒนาเขตเกษตรกรรมของดัตช์บนเกาะสุมาตราโดยเฉพาะบริเวณตะวันออกของสุมาตราเหนือครอบคลุมพื้นที่ของเดลี เซอดัง (Deli-Serdang) และเมืองเมดาน (Medan) ในปัจจุบัน พื้นที่ดังกล่าวถูกพัฒนาขึ้นให้กลายเป็นพื้นที่เกษตรกรรมสมัยใหม่ มีการเพาะปลูกพืชหลายชนิด โดยพืชเศรษฐกิจที่สำคัญที่สุดในพื้นที่ขณะนั้น คือ ใบยาสูบ ซIn the 19th Century, Deli-Medan received a large number of Chinese migrants. Most of them worked as labourers in Dutch agricultural plantations on the east coast of Sumatra, extending from Deli-Serdang to Medan. The agricultural products, such as tobacco, were intentionally developed and eventually became the most exportedproducts of Sumatra. As these economic activities paved the way for economic

Estimation of dissolved organic carbon from inland waters at a large scale using satellite data and machine learning methods

Dissolved Organic Carbon (DOC) in inland waters plays an essential role in the global carbon cycle and has significant public health effects. Machine learning (ML) together with remote sensing has emerged as a powerful and promising combination to quantify water quality parameters from space. However, inland water sample data for DOC is limited. Hence, little is known about the potential to quanti

Impact of pre-antiretroviral treatment HIV-RNA on time to successful virological suppression and subsequent virological failure - two nationwide, population-based cohort studies

Background: The impact of pre-antiretroviral treatment (ART) HIV-RNA on time to successful virological suppression and subsequent failure in HIV patients remains poorly investigated. Methods: We used the Swedish InfCareHIV database and the Danish HIV Cohort Study to evaluate impact of pre-ART HIV-RNA on primary virological suppression (HIV-RNA < 50copies/ml) and risk of secondary virological failu

A Systematic Review of Heterogeneity in Outcome Definition and Reporting in Localised Renal Cancer

Context: Outcomes in renal cell carcinoma (RCC) are reported inconsistently, with variability in definitions and measurement. Hence, it is difficult to compare intervention effectiveness and synthesise outcomes for systematic reviews and to create clinical practice guidelines. This uncertainty in the evidence makes it difficult to guide patient-clinician decision-making. One solution is a core out

K2-155 : A Bright Metal-poor M Dwarf with Three Transiting Super-Earths

We report on the discovery of three transiting super-Earths around K2-155 (EPIC 210897587), a relatively bright early M dwarf (V = 12.81 mag) observed during Campaign 13 of the NASA K2 mission. To characterize the system and validate the planet candidates, we conducted speckle imaging and high-dispersion optical spectroscopy, including radial velocity measurements. Based on the K2 light curve and

Exoplanets around Low-mass Stars Unveiled by K2

We present the detection and follow-up observations of planetary candidates around low-mass stars observed by the K2 mission. Based on light-curve analysis, adaptive-optics imaging, and optical spectroscopy at low and high resolution (including radial velocity measurements), we validate 16 planets around 12 low-mass stars observed during K2 campaigns 5-10. Among the 16 planets, 12 are newly valida

Three Small Planets Transiting a Hyades Star

We present the discovery of three small planets transiting K2-136 (LP 358 348, EPIC 247589423), a late K dwarf in the Hyades. The planets have orbital periods of 7.9757 ± 0.0011, 17.30681-0.00036+0.00034, and 25.5715-0.0040+0.0038 days, and radii of 1.05 ± 0.16, 3.14 ± 0.36, and 1.55-0.21+0.24 R⊕, respectively. With an age of 600-800 Myr, these planets are some of the smallest and youngest transit

K2-137 b : An Earth-sized planet in a 4.3-h orbit around an M-dwarf

We report the discovery in K2's Campaign 10 of a transiting terrestrial planet in an ultrashort- period orbit around an M3-dwarf. K2-137 b completes an orbit in only 4.3 h, the second shortest orbital period of any known planet, just 4 min longer than that of KOI 1843.03, which also orbits an M-dwarf. Using a combination of archival images, adaptive optics imaging, radial velocity measurements, an

Proteomic analysis of brain metastatic lung adenocarcinoma reveals intertumoral heterogeneity and specific alterations associated with the timing of brain metastases

Background: Brain metastases are associated with considerable negative effects on patients’ outcome in lung adenocarcinoma (LADC). Here, we investigated the proteomic landscape of primary LADCs and their corresponding brain metastases. Materials and methods: Proteomic profiling was conducted on 20 surgically resected primary and brain metastatic LADC samples via label-free shotgun proteomics. Afte