Evaluation of preventive effects of bioactive food compounds against oxidative stress and intestinal inflammation. Study in human reconstructed intestinal 3D tissue model.
This study investigated the effects of induced oxidative stress and inflammation on intestinal mucosal barrier function with specific objective to investigate counteracting potential of the proteolytic enzymes such as bromelain and papain using reconstructed human small intestinal 3D tissue model (SMI-100). Four physiological conditions were modeled: healthy conditions (intact, n=12), inflamed (IL
