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Treatment of chronic osteomyelitis by radical debridement and filling of the dead space with antibiotic containing calcium sulphate/hydroxyapatite (CaS/HA) bone substitute has shown excellent long-term outcomes. However, in extensive infections, sessile bacteria may remain in bone cells or soft tissues protected by biofilm leading to recurrences. The primary aim of this study was to evaluate if sy

I detta projekt har vi studerat organisationsformer och behov av digitalt stöd för mobila tvärprofessionella hemsjukvårdsteam vid vård av multisjuka äldre. Projektet är en direkt fortsättning på AFA-projektet ”Hur kan arbetsmiljön för personer inom hemsjukvården förbättras genom att e-hälsolösningar skapar kompetensstöd vid ensamarbete?”Projektets syfte är att undersöka hur organisering i mobila t

Utilizing passive floodwater harvesting for artificial recharge and spate irrigation in arid and semiarid areas is an opportunity to use marginal water to improve the livelihood of rural community. In the present study, ground- water modeling to estimate recharge, and field experiments for spate irrigation of barley, were carried out to investigate the performance and potential of water harvesting

Accumulating evidence from recent studies has indicated the importance of studying the interaction between the microvascular and lymphatic systems in the brain. To date, most imaging methods can only measure blood or lymphatic vessels separately, such as dynamic susceptibility contrast (DSC) MRI for blood vessels and DSC MRI-in-the-cerebrospinal fluid (CSF) (cDSC MRI) for lymphatic vessels. An app

Coal has long been one of the fossil fuels underpinning the energy systems of many countries around the world. Because of its long-standing history, many actors have an interest in retaining the status quo. In this article, we explore the complexities of a coal phase-out in different countries. Drawing on empirical material from Germany, India, Mexico, Serbia and South Africa, we look at the way c

BackgroundEarly detection of diabetes and hypertension is helpful to prevent and/or delay the onset of these diseases through proper interventions. Therefore, it is a prerequisite to know the prevalence of prediabetes and prehypertension and the factors associated with these conditions but people from developing countries including Bangladesh often remain undiagnosed and unaware of these condition

INTRODUCTION: Dysfunction of the cerebral vasculature is considered one of the key components of Alzheimer's disease (AD), but the mechanisms affecting individual brain vessels are poorly understood.METHODS: Here, using in vivo two-photon microscopy in superficial cortical layers and ex vivo imaging across brain regions, we characterized blood-brain barrier (BBB) function and neurovascular couplin

Accelerated by the harms and depletion risk of fossil fuels, transition to low-carbon or renewable fuels have become an urgent need for combustion engines to decarbonize transport sectors. Natural gas-diesel dual-fuel combustion is a promising method to achieve these goals by allowing the usage of natural gas in diesel engines. However, this concept has drawbacks of low combustion efficiency, high

We aimed to externally validate five previously published predictive models (Ng score, Triple D score, S3HoCKwave score, Kim nomogram, Niwa nomogram) for shock wave lithotripsy (SWL) single-session outcomes in patients with a solitary stone in the upper ureter. The validation cohort included patients treated with SWL from September 2011 to December 2019 at our institution. Patient-related variable

This study revisits the question of what impact Japanese colonialism had on the long-term economic development of North and South Korea. Factor endowments, economic activity and economic performance are compared between the regions that later became parts of North and South Korea, respectively. The study finds that important elements of the economic history of the peninsula have not been sufficien

Shape modification of embedded nanoparticles can be achieved by means of swift heavy ion irradiation. During irradiation, the particles elongate and align with the direction of the ion beam, presumably due to nanometer-scale phase transitions induced by individual ion impacts. However, the details of this transformation are not fully understood. The shape of metal nanoparticles embedded in dielect

Synergistic effects of nanosecond plasma discharge and hydrogen on the combustion characteristics of ammonia/air are numerically studied under conditions relevant to gas turbine combustion chambers. It is shown that increasing the plasma contribution in assisting the flame results in lower NOX emissions by up to 27% than those in flames assisted by hydrogen for the range of operating conditions co

Objective Longitudinal clinical registry-infrastructures such as Anti-Rheumatic Therapies in Sweden (ARTIS) allow simultaneous comparison of the safety of individual immunomodulatory drugs used in clinical practice, with consistent definitions of treatment cohorts, follow-up and outcomes. Our objective was to assess and compare incidence rates of key safety outcomes for individual targeted synthet

Background: Baleen whales are a clade of gigantic and highly specialized marine mammals. Their genomes have been used to investigate their complex evolutionary history and to decipher the molecular mechanisms that allowed them to reach these dimensions. However, many unanswered questions remain, especially about the early radiation of rorquals and how cancer resistance interplays with their huge n

Sustainability scholars increasingly recognize that policy mixes can positively impact socio-technical transitions. However, the temporal dimension of policy interventions remains under-researched, especially in the context of early transition dynamics that typically emerge in niche contexts. In this article, we explore how policy sequencing can play a key role in supporting the scaling-up of earl

Background & aim: Preterm infants risk deficits of long-chain polyunsaturated fatty acids (LCPUFAs) that may contribute to morbidities and hamper neurodevelopment. We aimed to determine longitudinal serum fatty acid profiles in preterm infants and how the profiles are affected by enteral and parenteral lipid sources. Methods: Cohort study analyzing fatty acid data from the Mega Donna Mega stud