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Purpose/Background: Ultra-high dose rate radiotherapy (RT) has shown potential for differential normal tissue (NT) sparing (a phenomenon termed the “FLASH effect”), particularly for larger fraction doses (>5 Gy). However, transitioning to hypofractionation may increase late-reacting NT toxicity, counteracting the FLASH effect. This study evaluates whether FLASH-RT can provide netsparing for organs
Magnesium (Mg) is an abundant metal which has been used in aviation, medicine, hydrogen energy storage, etc. However, Mg can be rather reactive, and therefore an improved understanding of corrosion and oxidation mechanisms can enhance the efficiency of these processes to control and widen applications. The study presented here investigates the mechanisms of oxidation from the initial to full monol
The effectiveness of exposure and response prevention (ERP), a front-line treatment for obsessive-compulsive disorder (OCD), is contingent on reducing engagement in compulsions, though recent research has found that certain compulsions may be less amenable to ERP. Given the impact of trauma exposure on OCD compulsions, the present study sought to examine whether compulsion-specific differences in
Objectives: 1. To validate catabolic meniscus explant models induced by cytokines: interleukin-6 + interleukin-6 receptor + tumor necrosis factor alpha (IL6/TNF) and oncostatin M + tumor necrosis factor alpha (OSM/TNF). 2. To evaluate three potential anti-catabolic treatments: i) dexamethasone (DEX), ii) a Link-N peptide (Link-N) and iii) a peptide from chondroadherin (CKF). Design: Healthy
Conventional lumped parameter models (LPMs) simulate coronary flow incorporating intramyocardial pressure and vascular compliance, but assuming constant resistance despite its dynamic changes during myocardial contraction. We developed a coronary LPM incorporating time-varying resistance, intramyocardial pressure and vascular compliance to simulate phasic flow, critically evaluating key contributi
Objective: Osteoarthritis (OA) is a common degenerative disease with a genetic contribution. However, no large nationwide family study concerning the heredity of OA has been published. This first nationwide study aimed to determine the familial risks of the main types of OA in twins, full-siblings, half-siblings, and cousins in Sweden. Design: The Swedish Multigeneration register was linked to the
Carbon capture and storage (CCS) has in recent years gained new attention in national and corporate strategies for achieving climate goals. This is for instance seen in Denmark, where CCS was positioned as the largest single mitigation tool in the 2020 Climate Programme. As an example of how international imaginaries of mitigation technologies translate into national settings, this paper explores
The current investigation explores the surface effects of quasiatomic layer etching (Q-ALE) of silicon (Si), focusing on the interplay of process parameters, such as Ar+ ion energy, and their impact on etch rate, surface roughness, and material damage. Using a chlorine-based reactive ion etching tool at varying radio frequency bias voltages, the ion energy distribution and etching characteristics
This study offers novel insights into parents' experiences of healthcare interactions during weight-related visits. Data were collected through the More and Less Europe study, a randomized controlled trial evaluating a parent support program for children (aged 2-6 years) with overweight or obesity in Sweden, Romania, and Spain to capture parents' experiences of healthcare interactions. Semi-struct
Through a systematic review this study critically examines existing peer-reviewed evidence on the often-overlooked gender dimensions of the just energy transition. We found 52 peer-review journal papers focusing on three main themes: (1) how energy production can worsen pre-existing gender-based vulnerabilities, (2) how energy consumption can reproduce gender-based energy poverty and (3) how femin
Background: Fatigue is a debilitating symptom in patients with primary mitochondrial disease nPMD). Developing new treatments that improve fatigue is a patient priority but is hampered by a lack of fit-for-purpose patient-reported outcome measures (PROMs). We aimed to understand the impact of fatigue on the lives of people with PMD and develop a brief PMD-specific PROM to evaluate fatigue in clini
Background: Dissecting free tissue flaps can be challenging and time-consuming. Imaging technologies are typically used to assist with preoperative planning. However, conventional methods have limitations that could potentially be overcome by extended reality technologies. This systematic review aimed to evaluate the current use of extended reality (XR) in preoperative planning for microsurgical f
Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor
Mini-Symposium Duration: 55 Minutes Contemporary evidence-based models support the early use of electric cars as mobility aids in children with motor disabilities. Monitoring how each child learns to interact with the car, and the learning progression is the key to adjusting the intervention strategies. The ALP 2.0 tool is a qualitative assessment that offers therapists and families a classificati
Rapid and accurate generation of building damage maps (BDMs) following earthquakes is crucial for effective disaster response and rescue operations. With the increasing availability of optical very high-resolution remote sensing (OVHR-RS) images, two considerable deep learning challenges arise: (1) developing robust models for data-rich regions and (2) adapting pre-trained models for areas with li
E-Poster, 2 minute presentation Abstract: Introduction: The tool Assessment of Learning Process (ALP) is to a high extent based on findings from the research project Driving to Learn (1993-2007), and collaboration with Durkin (2009-2016) and Kenyon (2020 -). The eight-phase ALP-Instrument is used to assess tool-use understanding across the full lifespan. Participants and Methods: Classic grounded
Lithium-ion battery safety is a topic of large importance, and testing is associated with large costs. Safety evaluation is therefore needed also at an early stage in cell design and development, in order to evaluate potential short-comings or to screen large platforms of materials and cells. Previous thermal runaway tests on lab-scale cells have, however, indicated differences in heat release and
E-poster, 2-minute presentation Statement of Problem Self-generated mobility, defined as the capacity for independent movement, plays a critical role in early childhood development. Limited mobility, often associated with conditions like cerebral palsy or muscular dystrophy, poses significant developmental delays, particularly impacting physical, social, and cognitive growth. Description of the Co
Description: Early interventions with PMDs can improve the independence and developmental outcomes of children with disabilities. Increasing awareness and interdisciplinary collaboration are essential to overcome barriers to access to PMDs. Expanding global partnerships and integrating PMDs into clinical and educational settings can increase children's access to mobility. ABSTRACT: Background The Description: Early interventions with PMDs can improve the independence and developmental outcomes of children with disabilities. Increasing awareness and interdisciplinary collaboration are essential to overcome barriers to access to PMDs. Expanding global partnerships and integrating PMDs into clinical and educational settings can increase children's access to mobility. ABSTRACT: Background The
E-poster, 2-minute presentation. ABSTRACT: Background: A study of typically developing infants testing joystick-operated powered wheelchair was part of the Driving to Learn project. The original aim was to find a pattern in achievements among participants with profound cognitive disabilities by comparing with young infants. Method: Re-analysis of video-data collected with typically developing infa
