Sökresultat

Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties.Genomic rearrangement is a common phenomenon in cance

Assemblies of different molecules is a prevalent phenomenon in nature, and crucial in biological life. Most of the biological assemblies are co-assembledcomposites, made up from several different components, either of thesame biomolecular type or a combination of different ones. Knowledge regarding amyloid fibril structure and the mechanism behind it has been elucidated through the development of

This chapter discusses broadly the challenges and opportunities for anthropologically engaging with the news media during a pandemic. It explores the Swedish experience, describing how the country was portrayed as reckless and irresponsible and the ways in which Swedish culture was used and misused to explain its handling of the pandemic. Anthropologists rely on news sources, to “set the scene,” t

BACKGROUND: There are multiple options for the treatment of thumb carpometacarpal joint osteoarthritis (CMC1 OA), with evidence for pain relief and improved function. Although simple trapeziectomy has the lowest complication risk, tendon suspension of the first metacarpal and interposition is still the most commonly used surgical procedure in patients with CMC1 OA. Although there are several repor

We study fully differential quarkonia photoproduction observables in ultraperipheral collisions as functions of momentum transfer squared. We employ the dipole picture of the QCD part of the scattering with proton and nucleus targets, with the projectile being a quasireal photon flux emitted by an incoming hadron. We analyze such observables for ground J/ψ, (1S) and excited ψ′, (2S) states whose l

Wurtzite-type zinc oxide (w-ZnO) is a widely used material with a pronounced structural anisotropy along the c axis, which affects its lattice dynamics and represents a difficulty for its accurate description using classical models of interatomic interactions. In this study, ab initio molecular dynamics (AIMD) was employed to simulate a bulk w-ZnO phase in the NpT ensemble in the high-temperature

Background: By 2030, the global population of people older than 60 years is expected to be higher than the number of children under 10 years, resulting in major health and social care system implications worldwide. Without a supportive environment, whether social or built, diminished functional ability may arise in older people. Functional ability comprises an individual's intrinsic capacity and p

Context. Young open clusters (ages of less than 200 Myr) have been observed to exhibit several peculiarities in their chemical compositions. These anomalies include a slightly sub-solar iron content, super-solar abundances of some atomic species (e.g. ionised chromium), and atypical enhancements of [Ba/Fe], with values up to ~0.7 dex. Regarding the behaviour of the other s-process elements like yt

Context. After more than 50 years, astronomical research still struggles to reconstruct the history of lithium enrichment in the Galaxy and to establish the relative importance of the various 7Li sources in enriching the interstellar medium (ISM) with this fragile element. Aims. To better trace the evolution of lithium in the Milky Way discs, we exploit the unique characteristics of a sample of op

The investigation of the phenomenon of dephasing assisted quantum transport, which happens when the presence of dephasing benefits the efficiency of this process, has been mainly focused on Markovian scenarios associated with constant and positive dephasing rates in their respective Lindblad master equations. What happens if we consider a more general framework, where time-dependent dephasing rate

In this review, we provide a short outlook of some of the current most popular pictures and promising approaches to non-perturbative physics and confinement in gauge theories. A qualitative and by no means exhaustive discussion presented here covers such key topics as the phases of QCD matter, the order parameters for confinement, the central vortex and monopole pictures of the QCD vacuum structur

Safe water and sanitation, which give rise to appropriate hygiene, are fundamental determinants of individual and social health and well-being. Thereby, assessing and widening access to sustainable, durable water and sanitation infrastructure remains a global health issue. Rural areas are already at a disadvantage. Poor access to water, sanitation, and hygiene (WASH) can have a major negative effe

Despite the growing surge in the literature about employee creativity, the mainstream literature largely views it from an organizational perspective, and ignores the underlying mechanism that motivates employees to be engaged in different creative tasks. Against this backdrop, the current work was carried out to explore the relationship of corporate social responsibility (CSR) and employee creativ

Global aging has raised increasing concerns on the health and well-being of older adults. Public transport is a viable option to improve the mobility and quality of life among older adults. However, policies that promote the public transport use among older adults are rare. This study utilizes the eXtreme Gradient Boosting (XGBoost) decision tree to explore the non-linear associations of the built

Screening for severe combined immunodeficiency (SCID) was introduced into the Swedish newborn screening program in August 2019 and here we report the results of the first year. T cell receptor excision circles (TRECs), kappa-deleting element excision circles (KRECs), and actin beta (ACTB) levels were quantitated by multiplex qPCR from dried blood spots (DBS) of 115,786 newborns and children up to

This paper evaluates six soft computational models along with three statistical data-driven models for the prediction of pan evaporation (EP). Accordingly, improved kriging—as a novel statistical model—is proposed for accurate predictions of EP for two meteorological stations in Turkey. In the standard kriging model, the input data nonlinearity effects are increased by using a nonlinear map and tr

Purpose: To describe parents' views of family-centered care at a pediatric intensive care unit. Design and Methods: A qualitative descriptive study with a deductive and inductive approach was conducted based on the principles of family-centered care. Inclusion criteria were parents of children cared for at a pediatric intensive care unit for at least 48 h. Parents of children who died during the h

BACKGROUND: Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast cancer patients. METHODS: We performed genome-wide association analyses within 15 subgroups of breast cancer patients based on prognostic factors, including hormone receptors, t

We study a model for frustrated tunneling ionization using ultrashort laser pulses. The model is based on the strong field approximation and it employs the saddle point approximation to predict quasiclassical trajectories that are captured on Rydberg states. We present a classification of the saddle-point solutions and explore their behavior as functions of angular momentum of the final state, as