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MicroRNAs (miRNAs) have emerged as pivotal regulators of gene expression, playing essential roles in diverse cellular processes, including the development and progression of cancer. Among the numerous proteins influenced by miRNAs, the MARCKS/MARCKSL1 protein, a key regulator of cellular cytoskeletal dynamics and membrane-cytosol communication, has garnered significant attention due to its multifa

AIM: To investigate the changes in prevalence and incidence of pharmacologically and non-pharmacologically treated diabetes in Sweden during 2005 to 2013.METHODS: We obtained data on gender, date of birth and pharmacologically and non-pharmacologically treated diabetes from national registers for all Swedish residents.RESULTS: During the study period a total of 240 871 new cases of pharmacological

AIMS: To investigate the individual characteristics, causes and circumstances around deaths in stimulant use, and to examine how individuals who died with stimulants in their body differ from individuals who died with opioids in their body.METHODS: This study includes individuals who died during the years 2000-2018 and underwent a forensic autopsy at Forensic Medicine in Lund, Skåne County, Sweden

Production of agricultural biofuels is expected to rise due to increasing climate change mitigation ambitions. Policy interventions promoting targeted bioenergy solutions can be motivated by the large environmental externalities present in agricultural systems and the local context of biomass production co-benefits. Introducing energy crops in crop rotations in arable land with depleted Soil Organ

Recent decades have seen the facilitation of unconventional or even extraordinary reproductive endeavours. Sperm has been harvested from dying or deceased men at the request of their wives; reproductive tissue has been surgically removed from children at the request of their parents; deceased adults´ frozen embryos have been claimed by their parents, in order to create grandchildren; wombs have be

We live in ‘Tomorrowland’; a land at the nexus of social science and natural science where the solution to our problems will be found tomorrow. The paper addresses the impossibility of international relations by proposing an alternative approach located in critical social theory. The paper utilises critical social theory to critique contemporary liberal assumptions and rationalisations of cultures

The Convention on the Rights of Persons with Disabilities (CRPD) sets out a new vision for mental health care with equality and self-determination as its core standards. The CRPD fundamentally challenges long-standing practices in Sweden including the use of involuntary hospitalization, treatment without consent, and the use of restraints. This article discusses the impact of this new vision on Sw

Dynamic resource management is a fairly recent development made to improve the flexibility of job scheduling. MPI-based approach [1] makes this possible by treating resources on a set granularity and performs set operations whenever changes are made. Due to the extreme resource requirements, using dynamic resources will likely be compulsory for parallel-in-time methods. Development towards this ha

This article investigates the geographies of subprime urbanization, and by extension, the displacement of 2007–08 financial crisis to the Global South. Previous research examined the formative ways that technological innovations enabled mortgages to deterritorialize and circulate on secondary markets. Less is known about how cities with underdeveloped financial systems and housing markets have bee

IntroductionThis study is part of an international collaboration that investigates teachers’ attitudes and responses to vignettes depicting school bullying situations. As per Bandura's model of reciprocal determination, attitudes and behavior in these situations can be influenced by individual and contextual factors. This study specifically examines several factors related to teachers ‘professiona

This open access anthology explores how legal proceedings in and out-of-court can be matched to the complex problems underlying disputes concerning child custody, residence and contact between parents. It focuses particularly on Nordic experiences of in and out-of-court mechanisms as means of resolving custody disputes. The findings by the internationally renowned contributors speak to an internat

Background The prevalence of mental health issues is rising, especially among youth. Research shows that diagnosable and subthreshold mood disorder symptoms are increasing. Notably, and particularly troublesome, there are indications that some mental health issues, such as non-suicidal self-injury (NSSI) and disordered eating (DE) behaviors, have increased during the last decades, these reports, h

BACKGROUND: Medication discrepancies in care transitions and medication non-adherence are problematic. Few interventions consider the entire process, from the hospital to the patient's medication use at home.AIM: In preparation for randomised controlled trials (RCTs), this study aimed (1) to investigate the feasibility of recruitment and retention of patients, and data collection to reduce medicat

En själ som Brutus’ och behag som Kleopatras. Så karaktäriserar upplysningsfilosofen Denis Diderot (1713–84) i ett brev den ryska kejsarinnan Katarina den stora, sedan han mött henne i S:t Petersburg i samband med en resa till Ryssland 1773–74. Diderot förespråkade jämlikhet, men var monarkist. Den perfekta regenten var en furste med det egna folkets väl som mål, menade han.En sådan filosofi kunde