Venous thromboembolism (VTE) clusters in families, but the familial risk of VTE has only been determined in first-degree relatives. This nationwide study aimed to determine the familial risk of VTE in first-, second- and third-degree relatives of affected individuals. The Swedish Multi-Generation Register was linked to Hospital Discharge Register data for the period 1987-2009. This was a case-coho

Aim: To investigate health-related quality of life (HRQoL) in young persons with limb reduction deficiency (LRD). Methods: One hundred and forty children with LRD aged 8-16 answered the DISABKIDS questionnaire for children with chronic health conditions. Of their parents, 137 answered a corresponding questionnaire concerning their child. Results: Compared to reference data from children with other

Recension av Kazimiera Ingdahl: Icke helt och hållet skall jag dö. Den ”judiska frågan” i Polen.

Dynamic chromatin structure is a fundamental property of gene transcriptional regulation, and has emerged as a critical modulator of physiological processes during cellular differentiation and development. Analysis of chromatin structure using molecular biology and biochemical assays in rare somatic stem and progenitor cells is key for understanding these processes but poses a great challenge beca

Popular Abstract in Swedish Östrogen är ett av de viktigaste/ mest studerade kvinnliga könshormonerna som styr utvecklingen av våra fortplantningsorgan och deras reproduktionsförmåga. Östrogen påverkar dessutom många av kroppens andra organ, bland annat hjärnan, skelettet, och hjärt-kärlsystemet. Mängden östrogen som finns i kroppen varierar vanligtvis under menstruationscykeln och med kvinnans ålEstrogen effects are mediated either through genomic action involving the classical estrogen receptors, estrogen receptor alpha (ERα) and beta (ERß), which function as transcription factors in the nucleus, or through rapid non-genomic action via receptors associated with plasma membrane. Recently, a member of the G protein-coupled receptor family was ascribed estrogen receptor properties and propo

At the end of the eighteenth century, Edward Gibbon described the antiquarian scholars of previous generations as men of “profound learning and easy faith.” His exemplar was the Swedish polymath Olof Rudbeck, who in a series of frantic and combative tomes sought to portray Sweden as the model for Plato’s Atlantis and the seething cultural cauldron from which Western civilization had emerged. A Pil

We consider steady symmetric gravity water waves on finite depth with constant vorticity and a monotone surface profile between crests and troughs. The problem is transformed into one concerning the vertical velocity. A representation formula for the stream function in terms of the surface and the vorticity is presented, and we show that the surface can be determined from the vertical velocity.

The aim of this study is to present diagnostic patterns, diagnostics used and antibiotic treatment in relation to guidelines in 3 repeated diagnosis-prescription studies conducted simultaneously in general practice in 5 Swedish counties, during 1 week in November 2000, 2002 and 2005. General practitioners (GPs) at the participating health centres were asked to complete a form for all patients with

The double sided silicon strip detector (DSSSD) is a segmented silicon detector commonly used in the fields of high energy physics and nuclear physics. This type of detector is used for analysis of reactions produced by charged particles. This makes it well suited for a number of analytical methods commonly used in ion beam analysis (IBA), such as Rutherford Backscattering (RBS) and elastic recoil

Popular Abstract in Swedish Allt liv på jorden är beroende av energi. Växter och vissa bakterier kan fånga och utnyttja solens energi för att bygga upp sina celler och dess delkomponenter som fetter, sockerarter och proteiner. Den energi som på så sätt blir bunden i dessa molekyler kan användas av djur och människor genom att vi konsumerar dem. För att energin skall kunna utnyttjas av kroppen måstSepsis is a devastating disease that is caused by the host’s response to an overwhelming infectious process. As sepsis progresses, organs distant from the site of infection become affected and sepsis-induced multiple organ failure ensues. An impaired immunologic response, including dysfunctional peripheral blood immune cells has been described as part of the septic syndrome. Mitochondrial dysfunct

Background: Local recurrence is a major factor affecting survival after treatment for head and neck squamous cell carcinoma (HNSCC). It is possible that the normal processes involved in wound healing after surgical removal of a primary tumor can boost the regrowth of residual cancer cells, thereby contributing to the recurrent growth. In this work, we collected human wound fluids and used them to

Central Asian countries are facing multidimensional political stability and security challenges in the post-Soviet period. Current scholarly discussions of political stability in post-Soviet Central Asia continue to revolve around the issues of Islamic upheaval, ethnic conflicts, civil war or inter-clan struggles, and how the authoritarian regimes in this region deploy coercive strategies and pena

This thesis explores different aspects of the syntax and discoursepragmatics of predicative anaphors(i.e. proforms and ellipsis)in German and Swedish. The types of anaphoric constructions considered in the analysis are: (i) overt predicative proform expressions, instantiated by the neuter proform "es"/"das" in German and "det" in Swedish, and (ii) covert elliptical instantiations, reminiscent of t

Background and purpose Spasticity and muscle contracture are two common manifestations of cerebral palsy (CP). A spastic muscle may inhibit growth in length of the muscle, but the importance of this relationship is not known. In 1994, a register and a healthcare program for children with CP in southern Sweden were initiated. The child's muscle tone according to the Ashworth scale and the ankle ran

Swedish children’s use of the headshake from 18 to 30 months shows a developmental progression from rote-learned coordination with speech to increasingly more flexible and productive coordination with speech. To deal with these observations, I introduce the concept of multimodal constructions in order to extend usage-based approaches to language learning and construction grammar into the kinetic d

Nuclear structure spectroscopy studies at GSI recently gained increased momentum within a broad international community with the installation of the Rare Isotopes Spectroscopic INvestigation at GSI (RISING) project. A wide range of physical phenomena has been addressed by high-resolution in-beam gamma-ray spectroscopy experiments with radioactive beams. Relativistic radioactive beams are implanted