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On a computational orientation-distribution-function-based remodelling framework

In this contribution, we apply the framework of orientation distribution functions (odf) to the modelling of adapting anisotropic biological tissues. Remodelling phenomena are thereby incorporated by means of an evolution equation for a generalised structural tensor so that the underlying odf evolves according to the local loading conditions.

A New Method for Analysis of Atrial Activation during Chronic Atrial Fibrillation in Man

To further clarify the mechanisms maintaining chronic atrial fibrillation (CAF), a method identifying preferable activation patterns of the atria during fibrillation, by time averaging of multiple discrete excitation vectors, was developed. Repeated recordings, each of 56 atrial bipolar electrograms simultaneously acquired during 8 s, were made at multiple sites in the right atrial free wall and t

Synthesis of hemes found in heme-copper oxidases of Bacillus subtilis

The last step of aerobic respiration, the reduction of dioxygen to water, is catalysed by terminal oxidases. These oxidases can be divided into two unrelated families, the heme-copper oxidases and the cytochrome bd-type oxidases. These enzymes contain two or more heme molecules as prosthetic groups. Heme is an iron-containing ring-closed tetrapyrrole. All eukaryotic and most bacterial oxidases bel

Exercise for breast cancer survivors: bridging the gap between evidence and practice

Evidence supporting the benefits of exercise following the diagnosis of breast cancer is overwhelming and compelling. Exercise reduces the severity and number of treatment-related side effects, optimizes quality of life during and following treatment, and may optimize survival. Yet, exercise does not uniformly form part of the standards of care provided to women following a breast cancer diagnosis