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Glycerol and urea are examples of small, water-soluble molecules with low vapor pressure that can protect lipid membranes upon dehydration. Both are a part of the Natural Moisturizing Factor in human skin, and are also present in other organisms, where they prevent drying due to osmotic stress. This study was conducted in order to understand the mechanism of such protection. We have selected two t

Legislation in Sweden and the European Union concerning the use of sewage sludge in agriculture is under revision and future concentration limits for pathogens in treated sludge are likely to be expected. The aim of this study was to evaluate the hygienization of Salmonella, Escherichia coli, Enterococcus and Clostridium perfringens through continuous anaerobic digestion at 35, 55 or 60 ºC as well

Negative pressure wound therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer reviewed publications are available describing its use. Despite this, there remains uncertainty regarding several aspects of usage. In order to respond to this gap a global expert panel was convened to develop evidence-based recommendations describing the use of NPWT. In this paper the result

The rate coefficients for the chemical reactions (species loss rates, quenching excluded) of the refrigerants CH2F2 (HFC-32), CHClF2 (HFC-22) and CH2FCF3 (HFC-134a), and the solvent CH3CCl3 with O(D-1) are determined relative to CH4 + O(D-1) at 298 K. The resulting rates k(CH2F2 + O(D-1)) = (4.78 +/- 1.03) x 10 (11) cm(3) molecule (1) s (1), k(CHClF2 + O(D-1)) = (8.69 +/- 1.72) x 10 (11) cm(3) mol

Modern power plants are all strongly dependent on reliable and accurate sensor readings for monitoring and control, thus making sensors an important part of any plant. Failing sensors can force a plant or component into non-optimal operation, cause complete shut-down of operation or in the worst case result in damage to components. Given their importance, sensors need regular calibration and maint

A common observation in recordings of neuronal activity from the cerebral cortex is that populations of neurons show patterns of synchronized oscillatory activity. However, it has been suggested that neuronal synchronization can, in certain pathological conditions, become excessive and possibly have a pathogenic role. In particular, aberrant oscillatory activation patterns have been implicated in

Subject-verb agreement in number (3sg - 3pl) in spoken French is a heterogeneous morpho-syntactic domain where number is expressed in some groups of verbs and in some phonological contexts only. The acquisition of this agreement is a long and gradual process (Prévost, 2009). Both children learning French as their first language (L1) and older second language (L2) learners overuse the dominant patt

In children’s literature nonhuman primates are often represented either as ferocious beasts or as curios and charmful vicarious children. In this article I demonstrate how these different constructions interestingly coexist in the popular story ‘‘The monkey that would not kill’’, written by the Scottish evangelist and professor of the natural sciences Henry Drummond in 1891. My study anchors the f

In this paper, we formulate the multi-pitch estimation problem and propose a number of methods to estimate the set of fundamental frequencies. The proposed methods, based on the nonlinear least-squares (NLS), Multiple Signal Classification (MUSIC) and the Capon principles, estimate the multiple fundamental frequencies via a number of one-dimensional searches. We also propose an iterative method ba

Handlingsutrymmet för kyrkans sociala engagemang har sett olika ut i olika tider, för att de senare decennierna öka i takt med att legala restriktioner minskat eller försvunnit. Relationen till staten har varit en styrande faktor för detta. I en omvärld alltmer präglad av marknadsvillkor och välfärdspluralism ställs nya krav. Ett sådant är att församlingar tydligare behöver artikulera vad de vill

PURPOSE. To demonstrate noninvasive imaging of human foveal capillary networks with a high-resolution, wide-field, dual-conjugate adaptive optics (DCAO) imaging instrument. METHODS. The foveal capillary networks of five healthy subjects with no previous history of ocular or neurologic disease or surgery were imaged with a novel high-resolution, wide-field DCAO instrument. The foveal avascular zone

Protection against mucosally transmitted infections probably requires immunity at the site of pathogen entry(1), yet there are no mucosal adjuvant formulations licensed for human use. Polyethyleneimine (PEI) represents a family of organic polycations used as nucleic acid transfection reagents in vitro and DNA vaccine delivery vehicles in vivo(2,3). Here we show that diverse PEI forms have potent m

This study investigates the internationalization of corporate boards, using a sample of 346 non-financial listed Nordic firms during 2001–2008. Given a high level of international activity, these firms have surprisingly few foreign directors. The picture of international expertise changes considerably, however, if we also count the international experience of national directors. The percentage of

By breeding TRAMP mice with S100A9 knock-out (S100A9(-/-)) animals and scoring the appearance of palpable tumors we observed a delayed tumor growth in animals devoid of S100A9 expression. CD11b(+) S100A9 expressing cells were not observed in normal prostate tissue from control C57BL/6 mice but were readily detected in TRAMP prostate tumors. Also, S100A9 expression was observed in association with

In many applications, especially in the process industry, low-level controllers are the workhorses of the automated production lines. The aim of this study has been to provide simple tuning procedures, either optimization-based methods or tuning rules, for design of low-order controllers. The first part of this thesis deals with PID tuning. Design methods or both SISO and MIMO PID controllers bas

We have measured electron energy spectra and asymmetry parameters of Ar clusters and Xe clusters illuminated by intense x-rays at 5 and 5.5 keV. A velocity map imaging spectrometer was developed for this purpose and employed at an x-ray free-electron laser facility, SACLA in Japan. The cluster size dependence and the peak fluence dependence of the electron spectra and asymmetry parameters are disc

Osteopetrosis caused by defective acid secretion by the osteoclast, is characterized by defective bone resorption, increased osteoclast numbers, while bone formation is normal or increased. In contrast the bones are of poor quality, despite this uncoupling of formation from resorption. To shed light on the effect of uncoupling in adult mice with respect to bone strength, we transplanted irradiated

Since 1986, 68% of the Listeria monocytogenes isolates from human cases of invasive listeriosis in Sweden are available for retrospective Studies. The aim of the present Study was to characterize 601 human invasive isolates of L. monocytogenes in Sweden from 1986 to 2007 by using serotyping and pulsed-field gel electrophoresis. Since 1996, serovar 4b was permanently reduced to the second or third