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Risks of alcohol and drug use disorders in prostate cancer survivors : a national cohort study

Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-

The Danish Trauma Database for Refugees (DTD) : A Multicenter Database Collaboration—Overcoming the Challenges and Enhancing Mental Health Treatment and Research for Refugees

Mental health of trauma-affected refugees is an understudied area, resulting in inadequate and poorer treatment outcomes. To address this, more high-quality treatment studies that include predictive analyses, long-term evaluations, cultural adaptations, and take account for comorbidities, are needed. Moreover, given the complex intertwining of refugees’ health with post-migration stressors and oth

European Respiratory Society clinical practice guideline : palliative care for people with COPD or interstitial lung disease

There is increased awareness of palliative care needs in people with COPD or interstitial lung disease (ILD). This European Respiratory Society (ERS) task force aimed to provide recommendations for initiation and integration of palliative care into the respiratory care of adult people with COPD or ILD. The ERS task force consisted of 20 members, including representatives of people with COPD or ILD

Exploring the knowledge contributions of carers involved in a group process aimed at co-creating a targeted support intervention

Patient and public involvement is a way of ensuring that research and practices are more responsive to their target groups. This study, inspired by discourse psychology, explores the knowledge contributions of informal carers who participated in group meetings to co-create a support intervention. Findings highlight that carers’ knowledge is complex, including more than practical caring experiences

Vad är en grupp?

Jag beskriver olika filosofiska teorier om vad grupper är, och skisserar kort min egen analys som jag utvecklat i mer detalj i en internationell artikel.

Flower Size as an Honest Signal in Royal Irises (Iris Section Oncocyclus, Iridaceae)

Flower traits, such as flower size or color changes, can act as honest signals indicating greater rewards such as nectar; however, nothing is known about shelter-rewarding systems. Large flowers of Royal irises offer overnight shelter as a reward to Eucera bees. A black patch might signal the entrance to the tunnel (shelter) and, together with the flower size, these might act as honest signals. We

BALDR : A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus

Novel biomarkers are key to addressing the ongoing pandemic of type 2 diabetes mellitus. While new technologies have improved the potential of identifying such biomarkers, at the same time there is an increasing need for informed prioritization to ensure efficient downstream verification. We have built BALDR, an automated pipeline for biomarker comparison and prioritization in the context of diabe

Executive Summary : Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus

BACKGROUND: Numerous laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. An expert committee compiled evidence-based recommendations for laboratory analysis in patients with diabetes. The overall quality of the evidence and the strength of the recommendations we

Prospective Attitudes towards Respiratory Syncytial Virus (RSV) Vaccination : Validation of a Survey Instrument among Young Females in Jordan Pending Vaccine Authorization

In May 2023, the U.S. FDA advisors endorsed Pfizer’s pregnancy-administered vaccine (branded ABRYSVO) to protect infants from respiratory syncytial virus (RSV) infection. Vaccination can reduce the burden of RSV-related respiratory disease, with previous studies showing its substantial medical and financial burden in Jordan. However, pregnant women may exhibit hesitancy to get vaccinated due to co

Association of TNF-α (-308G/A) Gene Polymorphism with Changes in Circulating TNF-α Levels in Response to CPAP Treatment in Adults with Coronary Artery Disease and Obstructive Sleep Apnea

Rationale: We recently demonstrated that patients with coronary artery disease (CAD) and obstructive sleep apnea (OSA) carrying the tumor necrosis factor-alpha (TNF-α) A allele had increased circulating TNF-α levels compared with the ones carrying the TNF-α G allele. In the current study, we addressed the effect of TNF-α (-308G/A) gene polymorphism on circulating TNF-α levels following continuous

Outcomes After Endovascular Aortic Intervention in Patients With Connective Tissue Disease

Importance: Endovascular treatment is not recommended for aortic pathologies in patients with connective tissue diseases (CTDs) other than in redo operations and as bridging procedures in emergencies. However, recent developments in endovascular technology may challenge this dogma. Objective: To assess the midterm outcomes of endovascular aortic repair in patients with CTD. Design, Setting, and Pa

Intake of the Total, Classes, and Subclasses of (Poly)Phenols and Risk of Prostate Cancer : A Prospective Analysis of the EPIC Study

Existing epidemiological evidence regarding the potential role of (poly)phenol intake in prostate cancer (PCa) risk is scarce and, in the case of flavonoids, it has been suggested that their intake may increase PCa risk. We investigated the associations between the intake of the total and individual classes and subclasses of (poly)phenols and the risk of PCa, including clinically relevant subtypes

Vector autoregression : Useful in rare diseases?—Predicting organ response patterns in a rare case of secondary AA amyloidosis

Background Statistical analyses of clinical data are a cornerstone in understanding pathomechanisms of disorders. In rare disorders, cross-sectional datasets of sufficient size are usually not available. Taking AA amyloidosis as an example of a life-threatening rare disorder resulting from of uncontrolled chronic inflammation, we propose techniques from time series analysis to predict organ respon

X-ray microtomography and 3D visualization of a plesiosaur propodial (Reptilia: Sauropterygia) from the Late Cretaceous of southern Sweden provides insights in bone histology, bone microstructures, and bone growth.

Polycotylid and elasmosaurid plesiosaurs inhabited the Kristianstad Basin during Late Cretaceous (uppermost lower Campanian Belemnellocamax mammillatuszone) around 80 million years ago. The setting represents one of the most famous Mesozoic fossil sites in Scandinavia. The Kristianstad Basin fossils are generally fragmentary and isolated due to high-energy environments in a protected shallow innerPolycotylid and elasmosaurid plesiosaurs inhabited the Kristianstad Basin during Late Cretaceous (uppermost lower Campanian Belemnellocamax mammillatuszone) around 80 million years ago. The setting represents one of the most famous Mesozoic fossil sites in Scandinavia. The Kristianstad Basin fossils are generally fragmentary and isolated due to high-energy environments in a protected shallow inner

Unstable Grounds: Reconfigurations of Performance and Politics

Critical StagesUnstable Grounds: Reconfigurations of Performance and PoliticsSpecial Issue, June 2021Gigi Argyropoulou and Stefanie SachsenmaierThis issue explores operations of performance during unstable conditions marked by socio-political, environmental, economic and further challenges. It is particularly interested in histories, reconfigurations and mutations of performance practice as it see

T-Helper 22 Cell Type Responses to Nickel in Contact Allergic Subjects Are Associated with T-Helper 1, T-Helper 2, and T-Helper 17 Cell Cytokine Profile Responses and Patch Test Reactivity

Introduction: Contact allergy to nickel (Ni) is a delayed-type hypersensitivity reaction mediated by Ni-reactive T cells producing the hallmark cytokines of several T-helper cell (Th) populations including IFN-γ(Th1), IL-4, IL-5 and IL-13 (Th2), and IL-17A (Th17). IL-22-expressing CD4+ cells, which could be either Th17 co-expressing IL-22 or Th22, expressing IL-22 in the absence of IL-17A, have al