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New study of babies in Skåne to prevent type 1 diabetes

Can insulin absorbed in small doses through food in early childhood get the immune system accustomed to insulin and thereby delay – or prevent – type 1 diabetes? Researchers hope to find the answer through POInT, a study starting in Skåne this autumn. Newborn babies in Skåne with a high risk of autoimmune diabetes (type 1 diabetes) can take part in the study. The infants from Skåne, together with

https://www.ludc.lu.se/article/new-study-babies-skane-prevent-type-1-diabetes - 2025-10-27

New discovery restores insulin cell function in type 2 diabetes

By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease. The findings are published in the scientific journal Cell Metabolism. The researchers at Lund University in Sweden

https://www.ludc.lu.se/article/new-discovery-restores-insulin-cell-function-type-2-diabetes - 2025-10-27

New findings on intestinal flora development in infants

In the so far largest clinical study of the development of microbiomes, i.e. intestinal flora, in infants, researchers at the Baylor College of Medicine, USA, have found that development takes place in different phases that can be associated with lifestyle changes during the early stages in life. The findings are based on samples from the TEDDY study and are published in two articles in the scient

https://www.ludc.lu.se/article/new-findings-intestinal-flora-development-infants - 2025-10-27

e-Health - what is needed for research to reach clinical benefit?

On November 30th a well-attended seminar rocusing on issues needed to consider already at an early stage when developing e-Health solutions was organized by LUDC Innovation Office, the Department of Clinical Sciences Malmö, and Medeon Science Park. Patrik Midlöv presented some examples of e-Health studies performed at the Medical Faculty.Henrik Ahlén, e-Health Strategist with extensive experience

https://www.ludc.lu.se/article/e-health-what-needed-research-reach-clinical-benefit - 2025-10-27

Metabolic research today and beyond

How far has precision medicine come? What challenges are we facing within clinical and translational research? See the seminar on metabolic research in retrospect. (Most of the lectures are held in Swedish) Precision medicine: a global overviewPaul Franks, professor, Lund University Diabetes CentreIn English Vilka är utmaningarna för den kliniska forskningen?Olle Stendahl, professor em, Linköpings

https://www.ludc.lu.se/article/metabolic-research-today-and-beyond - 2025-10-27

Register Now: FASEB Science Research Conference (SRC) – The Smooth Muscle Conference

Registration is now open for The Smooth Muscle Conference, taking place July 14-19, 2019, in West Palm Beach, Florida. Organized by Chairs Jonathan Jaggar, PhD, University of Tennessee; and Maria Gomez, PhD, Lund University, with support from the Federation of American Societies for Experimental Biology (FASEB), this conference is highly interactive and brings together an interdisciplinary group o

https://www.ludc.lu.se/article/register-now-faseb-science-research-conference-src-smooth-muscle-conference - 2025-10-27

Big data, muffins and space travel

What do muffins and space travel have in common? Answer: They affect our genes through altered DNA methylation patterns. Two researchers who studied this recently met at the public defence of a doctoral thesis at Lund University. Andrew Feinberg from Johns Hopkins University's School of Medicine in Baltimore, USA, has often been called the "father of epigenetics”.  When the US Space Agency NASA de

https://www.ludc.lu.se/article/big-data-muffins-and-space-travel - 2025-10-27

LUDC and President Obama have the same scientific advisor

Eric Lander, a long time collaborator of the diabetes researchers at LUDC, has been appointed as scientific advisor to Barack Obama, the new president of the United States. Eric Lander is an honorary doctor at the faculty of medicine at Lund University and member of the Scientific Advisory Board of LUDC. - It’s an honor, of course, but it's more the responsibility to serve right now, Eric Lander c

https://www.ludc.lu.se/article/ludc-and-president-obama-have-same-scientific-advisor - 2025-10-27

International Scientific congress on type 1 diabetes

350 international top scientists are gathering in Malmö to attend the 10th international congress of the Immunology of Diabetes Society (IDS). The focus of the congress will be on how to prevent and cure type 1 diabetes. -Malmö hosting such an event underlines Lund University Diabetes Centre’s (LUDC) position at the absolute scientific front. Not least when it comes to clinical studies aiming to p

https://www.ludc.lu.se/article/international-scientific-congress-type-1-diabetes - 2025-10-27

A unified European effort to fight diabetic complicati

In competition with about ten other European consortia, Lund University and collaborators have received a research grant of approximately 150 million SEK. The money, which is given by the European Union, will be complemented by funding from the pharmaceutical industry. The funding will be used to advance in the battle against complications caused by diabetic diseases. In addition to Lund Universit

https://www.ludc.lu.se/article/unified-european-effort-fight-diabetic-complicati - 2025-10-27

Unexpected link between diabetes and the sleep hormone melatonin

A common variant of the melatonin receptor gene increases the risk of developing type 2 diabetes. This discovery was made by two research groups at Lund University Diabetes Centre (LUDC), and reveals a completely new mechanism underlying diabetes. The finding, presented in the latest issue of the scientific journal Nature Genetics, also opens a new avenue for treating the disease. Finding that Mel

https://www.ludc.lu.se/article/unexpected-link-between-diabetes-and-sleep-hormone-melatonin - 2025-10-27

New risk markers discovered for cardiac infarction and stroke

Heart attack and stroke afflicts many in spite of them having few or no known risk factors such as high blood pressure, diabetes, changes in blood fat or smoking. -Because of this it is important to be able to identify those at risk who would benefit from preventive treatment, says Olle Melander, docent at Lund University and chief physician at Akutcentrum, UMAS. He is the main author of a new art

https://www.ludc.lu.se/article/new-risk-markers-discovered-cardiac-infarction-and-stroke - 2025-10-27

Food habits are more important than the most important obesity risk gene

The risk of becoming obese is 2.5 times higher for those who have double copies of the best known risk gene for overweight and obesity. However, this is only true if the fat consumption is high. A low fat diet neutralizes the harmful effects of the gene. “This means that the critical factor is what you eat. At least in the case of the FTO gene, the most important obesity gene identified so far” sa

https://www.ludc.lu.se/article/food-habits-are-more-important-most-important-obesity-risk-gene - 2025-10-27

A happy insulin cell needs to be sour

Type 2 diabetes is often not caused by a lack of insulin per se, but an inability of the beta cells to secrete adequate amounts of it. Recently, scientists at LUDC have identified a previously unknown agent that plays an important role in the release of insulin. Knock-out mice that lack the ClC3 protein have a severely diminished capacity to secrete insulin in spite of intact beta cells. This find

https://www.ludc.lu.se/article/happy-insulin-cell-needs-be-sour - 2025-10-27

Vaccine offered to children i Skania, Sweden, at high risk of diabetes

Children participating in the DiPiS and TEDDY studies, who are at high risk of developing type 1 diabetes, have the possibility to receive GAD vaccine. The hope is that this will stop the process and prevent the children from falling ill. Some of the children who have an increased risk of type 1 diabetes start producing antibodies directed at the insulin producing cells. This is a warning that the

https://www.ludc.lu.se/article/vaccine-offered-children-i-skania-sweden-high-risk-diabetes - 2025-10-27

Risk gene activates the stress system and increases the risk of diabetes

The finding of a new genetic risk variant and the description of the exact underlying mechanism explains, on a molecular level, the connection between stress and diabetes. This scientific breakthrough is published online today in the journal Science. Carriers of the risk variant have stressed insulin producing cells which greatly reduces their ability to secrete insulin. Further, making the findin

https://www.ludc.lu.se/article/risk-gene-activates-stress-system-and-increases-risk-diabetes - 2025-10-27

New mechanism underlying cardiovascular disease

Hyperglycemia starts a complex chain of events that damages blood vessels and cause cardiovascular disease. Scientists at Lund University Diabetes Centre (LUDC) have now been able to demonstrate why this happens, as well as how the destructive chain can be broken. This discovery represents a crucial step towards an efficient treatment of the vascular injuries that will be the cause of death for mo

https://www.ludc.lu.se/article/new-mechanism-underlying-cardiovascular-disease - 2025-10-27

The Royal Academy of Science praise diabetes professor

Leif Groop, professor in diabetes and endocrinology at the Department of Clinical Sciences in Malmö, Lund University, has been elected to recipient of Hilda och Alfred Erikssons prize of year 2010. Leif Groop receives the prize "for pioneering research about Type 2 Diabetes" whcih is the motivation by the Academy of Science.- An honorable acknowledgement  and it is always nice to be appreciated fo

https://www.ludc.lu.se/article/royal-academy-science-praise-diabetes-professor - 2025-10-27

Female hormone protects against diabetes

A recently discovered estrogen receptor in the insulin-producing cells may facilitate targeted diabetes treatment for women. The type 2 diabetes drugs that are currently available on the market have often only been tested on men. The identification of this new receptor may also explain why type 2 diabetes is less common in women than in men. "Estrogen is thought to have an important anti-diabetic

https://www.ludc.lu.se/article/female-hormone-protects-against-diabetes - 2025-10-27

Moving to Sweden increases the risk of diabetes

Children of immigrants from countries with low risk of type 1 diabetes develop the disease more often than expected if they grow up in Sweden, which is a high-risk country. Scientists mean that it is something in the Swedish environment that causes this elevated risk. Ahmed Delli, who is a scientist at Lund University Diabetes Centre, has mapped what happens when a child moves from an area with lo

https://www.ludc.lu.se/article/moving-sweden-increases-risk-diabetes - 2025-10-27