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Exploring the Role of 'Jumping Genes' in X-Linked Dystonia-Parkinsonism

New research is underway at Lund University, led by Dr. Vivien Horvath, a postdoctoral researcher at Lund Stem Cell Center. Supported by a new grant from the Collaborative Center for X-Linked Dystonia-Parkinsonism (XDP), Vivien aims to improve our understanding of XDP, a rare neurodegenerative disorder caused by the recent insertion of a transposable element. Transposable elements, also known as '

https://www.multipark.lu.se/article/exploring-role-jumping-genes-x-linked-dystonia-parkinsonism - 2025-10-05

Cell replacement therapy for Parkinson's Disease – Ph.D. interview with Fredrik Nilsson

Fredrik Nilsson defended his Ph.D. thesis on May 10, 2023. For the last four years, he has explored the use of patient-specific cells in cell replacement therapy for Parkinson's disease to identify strategies to safeguard these transplanted cells from disease-related degeneration. Now, he tells us about his findings, their potential implications for future therapies, and valuable insights and advi

https://www.multipark.lu.se/article/cell-replacement-therapy-parkinsons-disease-phd-interview-fredrik-nilsson - 2025-10-05

New Study Reveals Astrocytes' Role in Frontotemporal Dementia

One of Multipark's associated research groups has published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the journal Brain Communications, provide valuable insights into the cellular mechanisms of the disease and open up new possibilities for developing early diagnostics and potential interventions for patients with FTD

https://www.multipark.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-10-05

Summer greetings from MultiPark at the World Parkinson Congress

Summer is the right period for recharging our batteries through vacations and travels. It also seems to be an attractive time to organize scientific conferences… Here are some warm summer wishes from three MultiPark research group leaders and the MultiPark management team attending the World Parkinson Congress in Barcelona. Every third year, the World Parkinson Coalition organizes a breathtaking m

https://www.multipark.lu.se/article/summer-greetings-multipark-world-parkinson-congress - 2025-10-05

Lewy body disease can be detected before symptoms

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. The studies are published in Nature Medicine, where the researchers also demonstrate that reduced sense of smell is strongly linked to Lewy body disease even before ot

https://www.multipark.lu.se/article/lewy-body-disease-can-be-detected-symptoms - 2025-10-05

Electrotherapy without surgery

Researchers at Lund and Gothenburg Universities have successfully developed temporary, organic electrodes that can be seamlessly integrated into biological systems. The method, now published in Nature Communications, opens up a future where bioelectronics can be implanted in and removed from the body without surgery. Electrotherapy is a medical treatment method that uses electrical currents to sti

https://www.multipark.lu.se/article/electrotherapy-without-surgery - 2025-10-05

How psychedelic drugs affect a rat’s brain

Researchers at Lund University have developed a technique for simultaneously measuring electrical signals from 128 areas of the brain in awake rats. They have then used the information to measure what happens to the neurons when the rats are given psychedelic drugs. The results show an unexpected and simultaneous synchronisation among neurons in several regions of the brain. In light of the develo

https://www.multipark.lu.se/article/how-psychedelic-drugs-affect-rats-brain - 2025-10-05

Three researchers receive Barncancerfonden funding to investigate the causes of childhood leukemia

Each year, around 350 children in Sweden are diagnosed with cancer. Thanks to progress in research and treatment, six out of seven children today survive. But unlike cancer in adults, we don't know what causes most childhood cancers to develop. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes po

https://www.stemcellcenter.lu.se/article/three-researchers-receive-barncancerfonden-funding-investigate-causes-childhood-leukemia - 2025-10-05

Paul Bourgine awarded ERC Proof of Concept grant

Paul Bourgine, research group leader at Lund University's Lund Stem Cell Center, has been awarded an ERC Proof of Concept grant for his project CiThOss – Cellular immunoTHERapy modelling by exploitation of humanized OSSicles, which aims to develop accurate models for testing immunotherapies in cancer treatment. The European Research Council's Proof of Concept is awarded to researchers to investiga

https://www.stemcellcenter.lu.se/article/paul-bourgine-awarded-erc-proof-concept-grant - 2025-10-05

Why repetitive DNA matters for human brain evolution and disease

For decades, large stretches of human DNA were dismissed as ‘junk’ and considered to serve no real purpose. In a new study in Cell Genomics, researchers at Lund University in Sweden show that the repetitive part of the human genome plays an active role during early brain development and may also be relevant for understanding brain diseases. DNA carries the complete set of instructions an organism

https://www.stemcellcenter.lu.se/article/why-repetitive-dna-matters-human-brain-evolution-and-disease - 2025-10-05

Hjelt Diabetes Foundation supports research that can pave the way for new cell therapies

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation now provides support two diabetes researchers at Lund University working to learn more about diabetes. Among them is Associate Professor Isabella Artner, from the Lund Uni

https://www.stemcellcenter.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-10-05

Scientists uncover cellular “toolkit” to reprogram immune cells for cancer therapy

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in Immunity, could pave the way for more precise and personalised cancer immunotherapies. The team has taken an important step toward harnessing the immune system to fight cancer. Their work describes how

https://www.stemcellcenter.lu.se/article/scientists-uncover-cellular-toolkit-reprogram-immune-cells-cancer-therapy - 2025-10-05

ERC grant awarded to explore how the immune system shapes fertility

Why do some pregnancies succeed while others do not? With support from a newly awarded ERC Starting Grant, Assistant Professor Camila Consiglio and her team at Lund University’s Lund Stem Cell Center are embarking on a project to explore the role the immune system plays in fertility, and in determining reproductive success. Infertility is a deeply personal and global health issue, affecting one in

https://www.stemcellcenter.lu.se/article/erc-grant-awarded-explore-how-immune-system-shapes-fertility - 2025-10-05

Celebrating the art in science: Images from the 2025 Image Competition

The Lund Stem Cell Center’s Annual Image Competition returned this year with another vibrant display of creativity, curiosity, and scientific discovery. From intricate cellular landscapes to artistic interpretations of research, this year’s submissions once again highlighted the diverse and inspiring work of our research community. Now in its fourth year, the Lund Stem Cell Center Annual Image Com

https://www.stemcellcenter.lu.se/article/celebrating-art-science-images-2025-image-competition - 2025-10-05

Welcome two new Principal Investigators to Lund Stem Cell Center

Principal Investigators Daniella Ottosson and Charlotta Böiers have been accepted to join Lund Stem Cell Center.A warm welcome to the Ottosson and Böiers groups. To learn more about their research, the following Stem Cell Talks have been scheduled: Wednesday 25th September: Principal Investigator Daniella Ottosson. Details here.Wednesday 23rd October: Principal Investigator Charlotta Böiers. Detai

https://www.stemcellcenter.lu.se/article/welcome-two-new-principal-investigators-lund-stem-cell-center - 2025-10-05

Tailored therapy for chronic myeloid leukaemia

Chronic myeloid leukaemia (CML) is a slowly progressing form of blood cancer that attacks the blood-forming cells in the bone marrow. The condition requires lifelong treatment that can cause severe side effects. Rebecca Warfvinge maps stem cells in patients in the hope of identifying predictive markers for how the patient will react to therapy. She has now received an award of USD 20,000 from the

https://www.stemcellcenter.lu.se/article/tailored-therapy-chronic-myeloid-leukaemia - 2025-10-05

Cancerfonden supports research into the role of RNA modification in cancer development

The Swedish Cancer Foundation, Cancerfonden, has announced the researchers it will be supporting in its most recent round of funding and Lund Stem Cell Center was especially successful, with seven scientists awarded a total of almost 30 million SEK. Cristian Bellodi, a research team leader from the Division of Molecular Hematology, was awarded 12 million SEK - the largest grant to any researcher a

https://www.stemcellcenter.lu.se/article/cancerfonden-supports-research-role-rna-modification-cancer-development - 2025-10-05

Filipe Pereira awarded European Research Council Consolidator Grant

Today the European Research Council (ERC) announced the winners of its latest Consolidator Grant competition and Filipe Pereira, group leader in the Department of Laboratory Medicine, was one of the researchers awarded this highly competitive grant. One of 89 researchers selected from a total of 707 applicants in the area of Life Sciences, Filipe will be awarded 21 million SEK over five years. The

https://www.stemcellcenter.lu.se/article/filipe-pereira-awarded-european-research-council-consolidator-grant-0 - 2025-10-05

How self-reactive immune cells are allowed to develop

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive – they produce not only antibodies against foreign substances, but also against the body’s own substances, and it is unclear why the immune system allows for the devel

https://www.stemcellcenter.lu.se/article/how-self-reactive-immune-cells-are-allowed-develop - 2025-10-05