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Testosterone replacement therapy in men who conceived with intracytoplasmic sperm injection: nationwide register study

Male hypogonadism is associated with higher risk of co-morbidity and premature mortality. It is, therefore, of utmost importance to identify young men who are at the highest risk of testosterone deficiency and who may benefit from preventive measures. In this context, infertile men constitute a high-risk group. The extent of testosterone replacement therapy (TRT) among infertile men, defined as me

https://www.lupop.lu.se/article/testosterone-replacement-therapy-men-who-conceived-intracytoplasmic-sperm-injection-nationwide - 2025-11-13

C-reactive protein as a prognostic factor in intensive care admissions for sepsis: A Swedish multicenter study

C-reactive protein (CRP) is not included in the major intensive care unit (ICU) prognostic tools such as the Simplified Acute Physiology Score (SAPS). We assessed CRP on ICU admission as a SAPS-3 independent risk marker for short-term mortality and length of stay (LOS) in ICU patients with sepsis. New publication in Journal of Critical Care

https://www.lupop.lu.se/article/c-reactive-protein-prognostic-factor-intensive-care-admissions-sepsis-swedish-multicenter-study - 2025-11-13

Abbreviated Three-Item Versions of the Satisfaction with Life Scale and the Harmony in Life Scale Yield as Strong Psychometric Properties as the Original Scales

The cognitive components of subjective well-being can be measured with the Satisfaction with life scale (SWLS) and the Harmony in life scale (HILS), which both comprise five items each. The aim of this article is to abbreviate these scales and examine their psychometric properties and validity. Three datasets including test-retest data are used (N = 787; N = 860; N = 343). New publication in Journ

https://www.lupop.lu.se/article/abbreviated-three-item-versions-satisfaction-life-scale-and-harmony-life-scale-yield-strong - 2025-11-13

Cohort profile: the West Sweden Asthma Study (WSAS): a multidisciplinary population-based longitudinal study of asthma, allergy and respiratory conditions in adults

The West Sweden Asthma Study (WSAS) is a population-representative longitudinal study established to: generate data on prevalence trends, incidence and remission of asthma, allergy and respiratory conditions, elucidate on the risk and prognostic factors associated with these diseases, characterise clinically relevant phenotypes of these diseases and catalyse relevant mechanistic, genomic, genetic

https://www.lupop.lu.se/article/cohort-profile-west-sweden-asthma-study-wsas-multidisciplinary-population-based-longitudinal-study - 2025-11-13

The Validity of Registered Synchronous Peritoneal Metastases from Colorectal Cancer in the Danish Medical Registries

Treatment options for peritoneal metastases (PM) from colorectal cancer (CRC) have increased, their efficiency should be monitored. For this purpose, register-based data on PM can be used, if valid. Purpose: We aimed to evaluate the completeness and positive predictive value (PPV) of synchronous peritoneal metastases (S-PM) registered among CRC patients in the Danish National Patient Register (DNP

https://www.lupop.lu.se/article/validity-registered-synchronous-peritoneal-metastases-colorectal-cancer-danish-medical-registries - 2025-11-13

Difference in the risk profiles of carotid-femoral pulse wave velocity: results from two community-based studies in China and Sweden.

Carotid-femoral pulse wave velocity (cfPWV) and its risk factors may differ between various populations. Few studies have compared the risk profiles associated with cfPWV in different ethnic populations. The study population included 4321 subjects from Shanghai, China (n = 1272, age 75.0 ± 6.5 years, female 57.3%) and Malmö, Sweden (n = 3049, age 72.5 ± 5.5 years, female 60.4%). cfPWV was measured

https://www.lupop.lu.se/article/difference-risk-profiles-carotid-femoral-pulse-wave-velocity-results-two-community-based-studies - 2025-11-13

Data Resource Profile: The Systemic Anti-Cancer Therapy (SACT) dataset

The Systemic Anti-Cancer Therapy (SACT) database is a population-based resource of SACT activity reported routinely by National Health Service (NHS) trusts in England. Data are collected on the SACT treatments of adult and paediatric patients, delivered in secondary and tertiary settings with the intention of improving survival, delaying further cancer progression or development and improving dise

https://www.lupop.lu.se/article/data-resource-profile-systemic-anti-cancer-therapy-sact-dataset - 2025-11-13

Abatacept in rheumatoid arthritis: survival on drug, clinical outcomes, and their predictors—data from a large national quality register

There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. The aim of this study was to investigate clinical efficacy and tolerability of abatacept in RA, using a national register. New publication in BMC Arthritis Resea

https://www.lupop.lu.se/article/abatacept-rheumatoid-arthritis-survival-drug-clinical-outcomes-and-their-predictors-data-large - 2025-11-13

Data Resource Profile: National Cancer Registration Dataset in England

The National Cancer Registration and Analysis Service (NCRAS), part of Public Health England (PHE), is the population-based cancer registry for England. It collects, quality assures and analyses data on all people living in England who are diagnosed with malignant and pre-malignant neoplasms, with national coverage since 1971. It produces the national cancer registration dataset for England. The p

https://www.lupop.lu.se/article/data-resource-profile-national-cancer-registration-dataset-england - 2025-11-13

Risk of local recurrence of rectal cancer and circumferential resection margin: population‐based cohort study

A circumferential resection margin (CRM) of 1·0 mm or less after rectal cancer surgery is thought to increase the risk of local recurrence (LR). This retrospective population‐based study examined how CRM distance affects the LR risk. New publication in BJS Society

https://www.lupop.lu.se/article/risk-local-recurrence-rectal-cancer-and-circumferential-resection-margin-population-based-cohort - 2025-11-13

Data Resource Profile: The National Cancer Institute’s Health Information National Trends Survey (HINTS)

The National Cancer Institute’s (NCI) Health Information National Trends Survey (HINTS) was conceived in 1997 during a multidisciplinary conference focused on risk communication with attenders representing the fields of psychology, health behaviour and education, public health, clinical medicine and health journalism. The key recommendation born of this conference encouraged NCI to develop a commu

https://www.lupop.lu.se/article/data-resource-profile-national-cancer-institutes-health-information-national-trends-survey-hints - 2025-11-13

Covid-19 i trångbodda förorter

Genom ett gemensamt initiativ från Arbets-och miljömedicin i Stockholm, Göteborg och Lund har en tvärprofessionell arbetsgrupp bildats för att utifrån Folkhälsomyndighetens och Världshälsoorganisationens (WHO) riktlinjer ta fram anpassade hälsoråd till personer och familjer med boende i förorter och andra områden med stora förutsättningar för smittspridning. Läs mer på https://www.lupop.lu.se/ART.

https://www.lupop.lu.se/article/covid-19-i-trangbodda-fororter - 2025-11-13

Formas akututlysning 2020

Med anledning av Covid-19 och den rådande utvecklingen i Sverige och världen har Formas forskarråd beslutat att omgående öppna akututlysningen 2020. Formas vill inom rådets ansvarsområden, ge möjligheten att samla in data/forskningsmaterial av akut karaktär för att säkerställa framtida tillgänglighet för forskning. Läs mer på https://www.formas.se/arkiv/alla-utlysningar/utlysningar/2020-03-26-aku…

https://www.lupop.lu.se/article/formas-akututlysning-2020 - 2025-11-13

Reflection on modern methods: five myths about measurement error in epidemiological research

Epidemiologists are often confronted with datasets to analyse which contain measurement error due to, for instance, mistaken data entries, inaccurate recordings and measurement instrument or procedural errors. If the effect of measurement error is misjudged, the data analyses are hampered and the validity of the study’s inferences may be affected. In this paper, we describe five myths that contrib

https://www.lupop.lu.se/article/reflection-modern-methods-five-myths-about-measurement-error-epidemiological-research - 2025-11-13

About consent and old data

Updated FAQ regarding personal data on LU's project blog Påverkar dataskyddsförordningen hur vi behandlar gamla personuppgifterNär och hur bör vi använda samtycke som rättslig grund för behandling av personuppgifterVad gäller för gamla samtycken?Svaren hittar du på: https://personuppgifter.blogg.lu.se/faq/============Does the General Data Protection Regulation affect how we process old personal da

https://www.lupop.lu.se/article/about-consent-and-old-data - 2025-11-13

Using four different clinical tools as predictors for pain after total hip arthroplasty: a prospective cohort study

Treatment of postoperative pain remains a significant clinical problem, and prediction of patients with a risk of higher postoperative pain levels is an important focus. We aimed to identify patients undergoing total hip arthroplasty (THA) with risk of higher pain levels at 24 h postoperatively by using four simple and easily available clinical tools. New publication in BMC Anesthesiology

https://www.lupop.lu.se/article/using-four-different-clinical-tools-predictors-pain-after-total-hip-arthroplasty-prospective-cohort - 2025-11-13

Consumption of red meat, genetic susceptibility, and risk of LADA and type 2 diabetes

Analyses were based on Swedish case–control data comprising incident cases of LADA (n = 465) and T2D (n = 1528) with matched, population-based controls (n = 1789; n = 1553 in genetic analyses). Multivariable-adjusted ORs in relation to self-reported processed and unprocessed red meat intake were estimated by conditional logistic regression models. Attributable proportion (AP) due to interaction wa

https://www.lupop.lu.se/article/consumption-red-meat-genetic-susceptibility-and-risk-lada-and-type-2-diabetes - 2025-11-13