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Personal History of Diabetes as Important as Family History of Colorectal Cancer for Risk of Colorectal Cancer: A Nationwide Cohort Study

Diabetes mellitus (DM) and colorectal cancer (CRC) share some risk factors, including lifestyle and metabolic disturbances. We aimed to provide in-depth information on the association of CRC risk, especially early-onset CRC, with DM, family history of CRC, and age at DM diagnosis. Read more at https://journals.lww.com/ajg/Fulltext/2020/07000/Personal_History_of_Diabetes_as_Important_as.24.aspx

https://www.lupop.lu.se/article/personal-history-diabetes-important-family-history-colorectal-cancer-risk-colorectal-cancer - 2025-10-25

Prediction of Life Satisfaction in People with Parkinson’s Disease

People with Parkinson’s disease (PD) have lower life satisfaction (LS) than healthy peers. No study has yet identified predictors of LS in people with PD. Such information would be valuable for health care and future interventions that aim to maintain or increase LS. Read more at https://www.hindawi.com/journals/pd/2020/1561037/

https://www.lupop.lu.se/article/prediction-life-satisfaction-people-parkinsons-disease - 2025-10-25

New calls for proposal at VR

Eight new calls for proposal are now open The Swedish Research Council has now opened several calls for proposals within Natural and engineering sciences, Educational sciences and Development research. Most of the calls are open until 10 April, but the Network grant within Educational Sciences is open until 27 March.Read more at www.vr.se.

https://www.lupop.lu.se/article/new-calls-proposal-vr - 2025-10-25

Mortality and morbidity of low-grade red blood cell transfusions in septic patients: a propensity score-matched observational study of a liberal transfusion strategy

Red blood cell (RBC) transfusions are associated with risks including immunological reactions and volume overload. Current guidelines suggest a restrictive transfusion strategy in most patients with sepsis but based on previous randomized controlled trials and observational studies, there are still uncertainties about the safety in giving low-grade RBC transfusions to patients with sepsis. Read mo

https://www.lupop.lu.se/article/mortality-and-morbidity-low-grade-red-blood-cell-transfusions-septic-patients-propensity-score - 2025-10-25

Predictive Factors for Postoperative Pancreatic Fistula—A Swedish Nationwide Register-Based Study

Data from the Swedish National Registry for Pancreatic and Periampullary Cancer for all patients undergoing a PD from 2010 until 30th June 2018 were collected. The material was analysed in two groups, no POPF and clinically relevant (grade B and C) POPF. Read more at https://link.springer.com/article/10.1007/s00268-020-05735-4

https://www.lupop.lu.se/article/predictive-factors-postoperative-pancreatic-fistula-swedish-nationwide-register-based-study - 2025-10-25

Occurrence of cold sensitivity in carpal tunnel syndrome and its effects on surgical outcome following open carpal tunnel release

Cold sensitivity is common following nerve injuries in the upper extremity, but is less well studied in carpal tunnel syndrome (CTS). We investigated cold sensitivity in CTS and its effects on surgical outcome. A search of the Swedish National Registry for Hand Surgery (HAKIR) for open carpal tunnel releases (OCTR) from 2010–2016 identified 10,746 cases. Symptom severity questionnaires (HQ-8; HAKI

https://www.lupop.lu.se/article/occurrence-cold-sensitivity-carpal-tunnel-syndrome-and-its-effects-surgical-outcome-following-open - 2025-10-25

Cognitive test results are associated with mortality and rehospitalization in heart failure: Swedish prospective cohort study

Two hundred and eighty‐one patients hospitalized for HF (mean age, 74 years; 32% women) were assessed using cognitive tests: Montreal Cognitive Assessment (MoCA), A Quick Test of Cognitive speed, Trail Making Test A, and Symbol Digit Modalities Test. The mean follow‐up time censored at rehospitalization or death was 13 months (interquartile range, 14) and 28 months (interquartile range, 29), respe

https://www.lupop.lu.se/article/cognitive-test-results-are-associated-mortality-and-rehospitalization-heart-failure-swedish - 2025-10-25

Disentangling Social-Genetic From Rearing-Environment Effects for Alcohol Use Disorder Using Swedish National Data

Investigations of social-genetic effects, whereby a social partner’s genotype affects another’s outcomes, can be confounded by the influence of the social partner’s rearing environment. We used marital information on more than 300,000 couples from Swedish national data to disentangle social-genetic from rearing-environment effects for alcohol use disorder (AUD). Read more at https://journals.sagep

https://www.lupop.lu.se/article/disentangling-social-genetic-rearing-environment-effects-alcohol-use-disorder-using-swedish-national - 2025-10-25

Early versus late initiation of GH replacement in adult-onset hypopituitarism

Adult-onset growth hormone deficiency (AGHD) is usually the last deficiency to be substituted in hypopituitarism. In children with documented GH deficiency, treatment without delay is crucial for achieving optimal effects on growth and development. In adults, it is not known whether a delay in treatment initiation influences biochemical response and the favourable physiological effects resulting f

https://www.lupop.lu.se/article/early-versus-late-initiation-gh-replacement-adult-onset-hypopituitarism - 2025-10-25

Increases in the rates of primary and revision knee replacement are reducing: a 15-year registry study across 3 continents

Rates of knee replacement (KR) are increasing worldwide. Based on population and practice changes, there are forecasts of a further exponential increase in primary knee replacement through to 2030, and a corresponding increase in revision knee replacement. We used registry data to document changes in KR over the past 15 years, comparing practice changes across Sweden, Australia, and the United Sta

https://www.lupop.lu.se/article/increases-rates-primary-and-revision-knee-replacement-are-reducing-15-year-registry-study-across-3 - 2025-10-25

Formas' annual open call 2018 is now open

In the annual open call Formas welcomes applications within its three areas of responsibility - Environment, Agricultural Sciences and Spatial Planning. The purpose of the call is to enable researchers to address self-identified research needs and is divided into three sub-calls:Research and development projectsResearch and development projects for future research leadersMobility grantsThe latter

https://www.lupop.lu.se/article/formas-annual-open-call-2018-now-open - 2025-10-25

Association of acute myocardial infarction with influenza: A nationwide observational study

Influenza may precipitate cardiovascular disease, but influenza typically peaks in winter, coinciding with other triggers of myocardial infarction (MI) such as low air temperature, high wind velocity, low atmospheric pressure, and short sunshine duration. Read more at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236866

https://www.lupop.lu.se/article/association-acute-myocardial-infarction-influenza-nationwide-observational-study - 2025-10-25

Patterns of urinary albumin and IgM associate with markers of vascular ageing in young to middle-aged individuals in the Malmö offspring study

Increased urinary excretion of IgM and low-grade albuminuria are associated with increased risk of cardiovascular morbidity and mortality. The objective of this study was to investigate the association between urinary IgM, albuminuria, and vascular parameters reflecting arterial structure and function. Read more at https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-020-01638-3

https://www.lupop.lu.se/article/patterns-urinary-albumin-and-igm-associate-markers-vascular-ageing-young-middle-aged-individuals - 2025-10-25

Mental health and academic performance: a study on selection and causation effects from childhood to early adulthood

An inverse relationship between mental health and academic achievement is a well-known phenomenon in the scientific literature. However, how and when this association develops is not fully understood and there is a lack of longitudinal, population-based studies on young children. Early intervention is important if associations are to be found already during childhood. The aim of the present study

https://www.lupop.lu.se/article/mental-health-and-academic-performance-study-selection-and-causation-effects-childhood-early - 2025-10-25

Reversal Treatment in Oral Anticoagulant-Related Intracerebral Hemorrhage—An Observational Study Based on the Swedish Stroke Register

Intracerebral hemorrhage (ICH) is the most serious adverse effect of oral anticoagulant (OAC) treatment. The effect of OAC reversal therapy on outcome is uncertain. We compared 90-day survival and functional outcome in patients with OAC-ICH who received OAC reversal therapy with those who did not. Read more at https://www.frontiersin.org/articles/10.3389/fneur.2020.00760/full

https://www.lupop.lu.se/article/reversal-treatment-oral-anticoagulant-related-intracerebral-hemorrhage-observational-study-based - 2025-10-25

New study: Parents' metabolic traits can affect the child's health over time

New research at Lund University shows that the biological parents’ genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease. Previous research by diabetes researcher Rashmi Prasad has shown

https://www.ludc.lu.se/article/new-study-parents-metabolic-traits-can-affect-childs-health-over-time - 2025-10-25

New research track: higher amounts of dietary fibre before the age of two can reduce the later risk of coeliac disease

The results of an observational study from Lund University in Sweden are clear: up to the age of two, a more fibre-rich diet seems to reduce the risk of coeliac disease. A particularly clear link was seen when children had eaten fibre-rich foods before the age of one. “This is the first time the risk of coeliac disease has been studied based on fibre in children’s diets. But a clinical trial is al

https://www.ludc.lu.se/article/new-research-track-higher-amounts-dietary-fibre-age-two-can-reduce-later-risk-coeliac-disease - 2025-10-25

Hjelt Diabetes Foundation supports research that can pave the way for new cell therapies

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation provides support to two diabetes researchers at Lund University Diabetes Centre who contribute with new knowledge to this research field. Type 1 diabetes is a condition wh

https://www.ludc.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-10-25

International islet cell researchers met at conference in Malmö

International researchers who study islets of Langerhans met for a conference in Malmö in June. Studies of insulin-producing cells help us understand disease mechanisms in diabetes. Lund University Diabetes Centre and the strategic research area EXODIAB hosted the event. Lund University Diabetes Centre (LUDC) and the strategic research are EXODIAB (Excellence of Diabetes Research in Sweden) hosted

https://www.ludc.lu.se/article/international-islet-cell-researchers-met-conference-malmo - 2025-10-25

Charlotte Ling receives major grant for clinical diabetes research

Congratulations to Charlotte Ling who, together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. The funding will support clinical research in precision medicine, focusing on epigenetic analysis of blood samples from 13,000 individuals. Charlotte Ling, a professor in diabetes research with a particular focus on epigeneti

https://www.ludc.lu.se/article/charlotte-ling-receives-major-grant-clinical-diabetes-research - 2025-10-25