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What Now? Epidemiology in the Wake of a Pandemic

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 2 June 2021 Image from pixabay / pearson0612 The coronavirus disease 2019 (COVID-19) pandemic and the coming transition to a postpandemic world where COVID-19 will likely remain as an endemic disease present a host of challenges and opportunities in epidemiologic research. Read the paper at https://academic.oup.com/aje/article

https://www.lupop.lu.se/article/what-now-epidemiology-wake-pandemic - 2025-07-05

Reducing Bias Due to Exposure Measurement Error Using Disease Risk Scores

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 3 June 2021 Suppose that an investigator wants to estimate an association between a continuous exposure variable and an outcome, adjusting for a set of confounders. If the exposure variable suffers classical measurement error, in which the measured exposures are distributed with independent error around the true exposure, then

https://www.lupop.lu.se/article/reducing-bias-due-exposure-measurement-error-using-disease-risk-scores - 2025-07-05

Simulation as a Tool for Teaching and Learning Epidemiologic Methods

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 4 June 2021 Photo: Kennet Ruona In aspiring to be discerning epidemiologists, we must learn to think critically about the fundamental concepts in our field and be able to understand and apply many of the novel methods being developed today. We must also find effective ways to teach both basic and advanced topics in epidemiolog

https://www.lupop.lu.se/article/simulation-tool-teaching-and-learning-epidemiologic-methods - 2025-07-05

Factorial Mendelian randomization: using genetic variants to assess interactions

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 5 June 2021 Photo: Pixabay / Arek Socha Factorial Mendelian randomization is the use of genetic variants to answer questions about interactions. Although the approach has been used in applied investigations, little methodological advice is available on how to design or perform a factorial Mendelian randomization analysis. Read

https://www.lupop.lu.se/article/factorial-mendelian-randomization-using-genetic-variants-assess-interactions - 2025-07-05

Bias factor, maximum bias and the E-value: insight and extended applications

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 6 June 2021 Unmeasured confounding can bias the relationship between exposure and outcome. Sensitivity analyses generate bias-adjusted measures but these are not much used; this may change with the availability of the E-value (for evidence for causality in observational studies), appealing for its ease of calculation. Read the

https://www.lupop.lu.se/article/bias-factor-maximum-bias-and-e-value-insight-and-extended-applications - 2025-07-05

Reference-adjusted and standardized all-cause and crude probabilities as an alternative to net survival in population-based cancer studies

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 7 June 2021 Photo: Pixabay / Colin Behrens We illustrate the method and some potential choices using data from England for men diagnosed with melanoma. Various marginal measures are presented and compared. Read the paper at https://academic.oup.com/ije/article/49/5/1614/5896134

https://www.lupop.lu.se/article/reference-adjusted-and-standardized-all-cause-and-crude-probabilities-alternative-net-survival - 2025-07-05

PhD position in Economic History: Neighborhood effects over the life course

Published 27 May 2021 Fotograf: Håkan Röjder The PhD position is linked to the research project The long reach of the neighborhood: Health, education and earnings in Landskrona, Sweden, 1904-2015, funded by Handelsbankens forskningsstiftelser. The PhD student will work in this project in collaboration with other project members and will be affiliated with the Centre for Economic Demography at LUSE

https://www.lupop.lu.se/article/phd-position-economic-history-neighborhood-effects-over-life-course - 2025-07-05

Reflection on modern methods: planned missing data designs for epidemiological research

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 16 June 2021 Photo: Pixabay / Gerd Altmann This paper describes the multiform, wave-missing and two-method designs, including their benefits, their impact on bias and power, and other factors that must be taken into consideration when implementing them in an epidemiological study design. Read the paper at https://academic.oup.

https://www.lupop.lu.se/article/reflection-modern-methods-planned-missing-data-designs-epidemiological-research - 2025-07-05

Obesity reprogrammes muscle stem cells

Published 23 February 2017 Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden. In a new study, doctoral student Cajsa Davegårdh has studied so-called DNA methylation in muscle stem cells in both obese and non-obese individuals. D

https://www.ludc.lu.se/article/obesity-reprogrammes-muscle-stem-cells - 2025-07-05

An Innovative Medicines Initiative Project for Precision Medicine in DKD

Published 24 February 2017 BEAt-DKD (“Biomarker Enterprise to Attack Diabetic Kidney Disease”), a unique public private partnership funded by the Innovative Medicines Initiative (IMI), member companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA), the Juvenile Diabetes Research Foundation (JDRF) and the state of Switzerland has announced the launch of a 5-¬¬ye

https://www.ludc.lu.se/article/innovative-medicines-initiative-project-precision-medicine-dkd - 2025-07-05

100 million SEK for personalized medicine in Diabetes

Published 24 February 2017 Almost 0.5 billion people have diabetes globally, many of whom are unaware of their condition; within the next two decades, this number is expected to double, largely owing to a growing, ageing, and increasingly industrialized global population. Lund University receives 100 million SEK from The Swedish Foundation of Strategic Research to help stop this development. “This

https://www.ludc.lu.se/article/100-million-sek-personalized-medicine-diabetes - 2025-07-05

Unique mapping of methylome in insulin-producing islets

Published 24 February 2017 Throughout our lives, our genes are affected by the way we live. Diet, exercise, age and diseases create imprints that are stored in something called methylome. Now, for the first time, researchers at the Lund University Diabetes Centre in Sweden have been able to map the entire methylome in the pancreatic islets which produce insulin, and the researchers have made sever

https://www.ludc.lu.se/article/unique-mapping-methylome-insulin-producing-islets - 2025-07-05

Ten postdocs kick off excellence programme for sustainable development

Published 21 June 2021 Three research projects involving a total of 10 postdocs received a total of SEK 23.5 million in the first round of Lund University’s research programme for excellence, focusing on Agenda 2030 and sustainable development. In March this year, Lund University announced SEK100 million in funding for a research programme for excellence,focusing on Agenda 2030 and sustainable dev

https://www.lunduniversity.lu.se/article/ten-postdocs-kick-excellence-programme-sustainable-development - 2025-07-05

A soundwalk from the future imagines climate transition

Published 28 June 2021 “It’s 2050. Selma is dead. But before she is buried, she wants to talk to a person from 2021 and show them how, in Malmö, everything is possible. That person is you.” That is the dramatic beginning of a climate soundwalk that gives the listener the opportunity to imagine how Malmö, Sweden, might be affected by climate change over the coming 30 years. The project is a collabo

https://www.lunduniversity.lu.se/article/soundwalk-future-imagines-climate-transition - 2025-07-05

Astonishing altitude changes in marathon flights of migratory birds

Published 1 July 2021 A great snipe in Jämtland, Sweden (Photo: Åke Lindström) Extreme differences in flight altitude between day and night may have been an undetected pattern amongst migratory birds – until now. The observation was made by researchers at Lund University in Sweden in a study of great snipes, where they also measured a new altitude record for migratory birds, irrespective of the sp

https://www.lunduniversity.lu.se/article/astonishing-altitude-changes-marathon-flights-migratory-birds - 2025-07-05

Drug dissolved net-like structures in airways of severely ill Covid-19 patients

Published 1 July 2021 The image to the far left is from sputum prior to treatment with the DNase drug. The one in the middle was taken 3.5 days after treatment, and the one to the far right was taken the day the patient was discharged. When researchers at Lund University in Sweden performed advanced analyses of sputum from the airways of severely ill Covid-19 patients, they found high levels of ne

https://www.lunduniversity.lu.se/article/drug-dissolved-net-structures-airways-severely-ill-covid-19-patients - 2025-07-05

Nobel Prize winning microscopy technique uncovers mechanisms of bacterial antibiotics resistance

By agata [dot] garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 6 July 2021 Cryo-EM generated image of an antibiotic resistance factor (pink) protecting the protein factory, the ribosome, (white/grey). he reistance factor pushes its "arm" into the ribosome to remove the drug. Image credit: Hauryliuk-Atkinson lab To counter the effects of antibiotics, bacteria constantly evolve

https://www.lunduniversity.lu.se/article/nobel-prize-winning-microscopy-technique-uncovers-mechanisms-bacterial-antibiotics-resistance - 2025-07-05

Precision medicine is an emerging approach for complex diseases

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 6 July 2021 Researchers at Lund University Diabetes Centre are studying whether different subgroups of diabetes need different treatment. Photo: Kennet Ruona Newborn babies are already being screened for mutations and genetic tests help families with hereditary breast cancer. Genomic-driven precision medicine (GDPM) is an

https://www.lunduniversity.lu.se/article/precision-medicine-emerging-approach-complex-diseases - 2025-07-05

Artificial light disrupts dung beetles’ sense of direction

Published 29 July 2021 A nocturnal dung beetle climbing atop its dung ball to survey the stars before starting to roll (Photo: Chris Collingridge) For the first time, researchers have been able to prove that city lights limit the ability of nocturnal animals to navigate by natural light in the night sky. Instead, they are forced to use streetlamps, neon light or floodlights to orient themselves. T

https://www.lunduniversity.lu.se/article/artificial-light-disrupts-dung-beetles-sense-direction - 2025-07-05