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Celiac disease prediction in Skåne The Celiac disease Prediction in Skåne is a spin-off investigation for celiac disease using the DiPiS cohort. It tested to what extent the tissue transglutaminase autoantibodies (tTG IgG or IgA) predict celiac disease (CD). It also tested whether environmental factors other than gluten may initiate the disease process. The genetic factor with the highest risk for

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/cipis - 2025-10-27

The Environmental Determinants of Diabetes in the Young The TEDDY study focuses on studying the role of environmental factors among children who are genetically susceptible to develop T1D. Several environmental factors are incriminated in the etiology of T1D such as gestational and childhood viral infections to such as changes in the gestational environment and infancy feeding, exposure to toxic s

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/teddy - 2025-10-27

Better Diabetes Diagnosis The BDD study is a nationwide prospective cohort study that recruits new-onset T1D who are less than 18 years old at time of diagnosis. There are 40 pediatric medical centers (95% of pediatric centers in Sweden) from most parts of Sweden participating in the BDD study. The BDD study started recruiting new incident patients of T1D from May 1st, 2005 and is still ongoing. C

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/bdd - 2025-10-27

The Global Diabetes Alliance Background The Global Diabetes Alliance (GDA) is a not-for-profit international alliance, established in 2007 and steered by a multinational collaborative panel of leading scientists in the field of diabetes. The GDA is forming a growing ‘virtual diabetes research community’, that is responding to the “tsunami” of diabetes, which threatens the well-being of millions of

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/gda - 2025-10-27

DIAbetes type 1 Prediction, Early Pathogenesis and Prevention The collaborative project DIAPREPP specifically addresses the call FP7 Cooperation Work Programme: Health-2007-2.4.3-1 Early processes in the pathogenesis of type 1 diabetes and strategies for early prevention.  The coordinator is Ezio Bonfacio, Dresden, Germany. The earliest currently identifiable process in the pathogenesis of type 1

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/diaprepp - 2025-10-27

Diabetes Prevention - Immune Tolerance DiAPREV-IT is the first prevention trial with DiamydTM, the alum formulated GAD65 “vaccine”, in children with positive islet cell autoantibodies but not yet diabetes. In the investigator initiated, placebo controlled, and double blind study, children from 4 years of age with positive GAD65-antibodies and at least one more positive islet cell autoantibody will

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/diaprev-it - 2025-10-27

Retinopathy After Diabetes Onset Diabetes retinopathy (DR) refers to any of the vascular changes in the retina. These are observed clinically as microaneurysms, dot and blot hemorrhages, edema, hard and soft exudates, neovascularization and newly formed fibrovascular tissue. The major sight-threatening manifestations of DR, macular edema and proliferative diabetes retinopathy, PDR, are the end res

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/read - 2025-10-27

Diabetes and cardiovascular risk factors DOHK is the acronym for the Swedish Diabetes och Hjärta-Kärl.   Patients diagnosed with diabetes have an increased risk to develop cardiovascular complications such as acute myocardial infarction (AMI) and stroke. Up to today, about 30 different genes have been identified as predisposing for type 1 diabetes. Furthermore, about 60 different genes have shown

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/dohk - 2025-10-27

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https://www.ludc.lu.se/research/diabetic-complications/research-areas - 2025-10-27

Researcher profiles

https://www.ludc.lu.se/researcher-profiles - 2025-10-27

Substances in the food we eat stress the insulin-producing beta cells to death. Albert Salehi conducts research on how the beta cells function, and believes in new anti-diabetic drugs that can protect the beta cells and prevent type 2 diabetes. After studying pharmacology at Linköping University, Albert Salehi wanted to go on to study medicine. By chance he came into contact with Professor Ingemar

https://www.ludc.lu.se/beta-cells-diet-and-new-drugs - 2025-10-27

The focus of Hindrik Mulder’s research is on the metabolism of insulin-producing beta cells. The question he studies is what goes wrong in type 2 diabetes: why do the insulin-producing beta cells fail? Why are they no longer able to release as much insulin as is needed to keep blood sugar levels under control? “The cells’ powerhouses – mitochondria – play a key role in this. The mitochondria give

https://www.ludc.lu.se/dantes-circles-hell-academic-freedom - 2025-10-27

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https://www.ludc.lu.se/research-0/molecular-epidemiology-and-cardiology/maya-karbalaei-sadegh-phd - 2025-10-27

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https://www.ludc.lu.se/research-0/molecular-epidemiology-and-cardiology/anna-egerstedt-md - 2025-10-27

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https://www.ludc.lu.se/research-0/molecular-epidemiology-and-cardiology/grunde-gjesdal-md - 2025-10-27

The Botnia study was initiated in 1990 on the western coast of Finland in the Gulf of Bothnia with the aim to:Characterize the early metabolic defects in individuals at risk of developing type 2 diabetesIdentify genetic variants predisposing to type 2 diabetesStudy how the identified genetic markers and biomarkers can predict the development of type 2 diabetes and progression of the diseaseIdentif

https://www.ludc.lu.se/botnia - 2025-10-27

Aida Koder HamidEsther González Padilla

https://www.ludc.lu.se/research-0/nutritional-epidemiology/summer-students - 2025-10-27

Lund University Diabetes Centre Industrial Research Centre (LUDC-IRC) is an Industrial Research Centre for personalized medicine in diabetes.Vision: The right prevention and treatment, for the right patients at the right time.Mission: A holistic approach towards improved diagnosis, prevention and treatment of diabetes.Funding (2017-2024): 75 MSEK from SSF. 25 MSEK from industrial partners.Number o

https://www.ludc.lu.se/ludc-irc - 2025-10-27

ANDiS (All New Diabetics in Scania) is a regional research project in southern Sweden. The population of the region is just over one million. All newly diagnosed patients at all ages in the Scania region will be included during 2009-2013.The aim of the registry is to describe the spectrum of diabetes subgroups in southern Sweden and to link genetic and phenotypic information at diagnosis of diabet

https://www.ludc.lu.se/andis - 2025-10-27

Non-coding RNAs in beta cell insulin secretion - emerging players in Type 2 Diabetes pathogenesis Type 2 diabetes (T2D) is a complex polygenic disease influenced by both environmental and genetic factors resulting in impaired insulin release from pancreatic beta cells and insulin resistance in target tissues. The incidence of T2D is escalating and it is projected that over 640 million people will

https://www.ludc.lu.se/education-training/theses/theses-2017/jones-ofori - 2025-10-27