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Direct neuronal reprogramming has many medical applications that are at the forefront of medical research. There are known genes, such as Ascl1, Dlx5 and Lhx6, that induce the reprogramming into neuronal cells. However, because there are numerous genetic variables involved in direct reprogramming, the current methods for conversion is inefficient. Hence, we proposed a strategy to group genes and m

Demokratier nedmonteras i stater runtom i världen. För att undvika och återhämta sig från demokratisk nedmontering är det viktigt att stater kan bibehålla eller förbättra sina nivåer av demokrati. Detta koncept är känt som ’democratic resilience’ eller demokratins motståndskraft. Demokratiers nedmontering har en negativ inverkan på människors möjlighet att åtnjuta mänskliga rättigheter, varför säkDemocracy is declining in several states in all regions of the world. To avoid and recover from democratic backsliding, it is important that states can maintain or improve their levels of democracy. This concept is commonly referred to as ‘democratic resilience’. Democratic backsliding has a negative impact on the ability of people to enjoy their human rights, and therefore, there must be a safety

Denna studie har undersökt hur hög- och lågavlönade skiljer sig i personlighet och intelligens. Studien har besvarat frågeställningen “Vad finns det för samband mellan specifika personlighetsdrag, intelligens och hur ekonomiskt framgångsrik någon blir?”. Undersökningen utgjordes av en kvantitativ metod med enkäter som grund för datainsamlingen. Enkäten inkluderade ett IPIP-NEO-30 personlighetstestThe aim of this study was to examine how high paid and low paid individuals differ when it comes to personality and intelligence. The study has answered the following research question; “What is the relationship between specific personality traits, intelligence and how financially successful someone becomes?”. The study consisted of a quantitative method with questionnaires as the basis for the da

Traditionell produktutveckling har en tendens att förlita sig på fysiska prototyper och produkttester för att kunna presentera koncept, förbättra design och kalibrera tillverkningsinställningar. Detta projekt undersöker och utvärderar en virtualisering av prototypframtagning och testning av en plastprodukt för att se om det kan resultera i en snabbare produktframtagning och besparingar av utveckliTraditional product development tends to heavily rely on physical prototyping and testing to present concepts, improve design, and calibrate manufacturing settings. This project aims to explore and evaluate a virtualization of prototype development and testing of a plastic product to evaluate if it results in a faster product development process and savings in development costs, as well as a more

The aim of the study was to investigate how professionals working with men who are victims of violence in heterosexual relationships perceive how norms and expectations in society affect the target group and the work in this field. The empirical material was based on eight interviews with professionals in different parts of Sweden who have come into contact with the target group in their work. The

This thesis explores how to design vehicle restraint systems specifically for Nordic climates. Cargo trucks prematurely departing from loading bays can cause serious damage to goods and personnel. To combat this problem vehicle restraint systems are commonly used to physically keep the trucks in place. However, many of these systems require permanent installations in front of the loading dock, mak

This study explores the description of underage children in criminal gangs, and how they’re depicted as either victims’ or perpetrators’ within documents that regulate Swedish authorities that work with children in criminal gangs; the Justice Department and the Government, Socialstyrelsen, the Police Department, Brottsförebyggande rådet (BRÅ), Statens beredning för medicinsk och social utveckling

Den globala plastindustrin är fast i ett fossilberoende som sipprar ner till många olika delar av samhället. Det finns så många användningsområden för plast att individer som del av samhället också fastnar i beroendet. Den här studien har utforskat ett tidigare outforskat område, nämligen discgolf, en liten men snabbt växande sport, ur ett hållbarhetsperspektiv. Fokus ligger på såväl tillverkarnasThe sport of disc golf has grown rapidly during the last five years, meaning a rapid increase in production of discs, and therefore also in the use of virgin plastics. The discs are usually produced with thermoplastic polyurethane (TPU) or thermoplastic elastane (TPE). The disc golf market is dominated by a handfull of brands that all have one thing in common, their work on sustainability is eithe

Varje sommar publicerar Jordbruksverket en prognos för hur stora skördarna av tretton viktiga grödor kommer att bli det året. Den låter både bönder och livsmedelsföretag planera sin verksamhet. Därför är det viktigt att prognoserna är så bra som möjligt. Hur stora skördarna blir per odlad hektar (den s.k. hektarskörden) varierar mellan grödor och beror bl.a. på jordmånen och vädret. JordbruksverkeEvery summer the Swedish Department of Agriculture publishes a forecast of the national harvest of 13 key cereal and oilseed crops. The yield of each crop in each region is modeled individually based on weather observations using linear regression and empirically known relationships. This thesis investigates and improves these models. First, the forecasts are replicated along with simulation-based

This thesis investigates the strategies and challenges related to the gender wage gap within Sweden’s white-collar sector, exploring how cultural norms and institutional policies impact wage disparities. With a qualitative approach, semi-structured interviews were conducted with professionals across various sector branches to gather diverse perspectives on the gender wage gap. The research aimed t

Design-forward portable lighting was introduced during the 2010’s, and has since solidified its presence and popularity. Made visible through restaurants and hotels it has grown into an attractive section of the lighting market. Through the flexibility of the cordless lamp, new creative design solutions have been achieved, and most design-forward companies include them in their range. Lighting d

Alzheimers sjukdom är den vanligaste typen av demenssjukdom. Den har drabbat miljontals människor, men ännu finns det inget sätt att bota sjukdomen. Huvudorsaken till Alzheimers sjukdom tros vara ansamlingar i hjärnan av peptiden amyloid β som självmant kan interagera med andra peptider av sin sort och bilda mycket stabila och organiserade amyloida fibriller. En mängd monomera amyloida β peptider The aggregation of amyloid β in the brain is considered to be the main cause of the currently incurable Alzheimer’s disease. Research investigating fibrils is being conducted continuously. Despite this, there is an incredibly large knowledge gap in what we know about the aggregation process. This study aims to investigate the temperature influence on the Aβ40 aggregation process using differential

Sand and dust storms (SDS) represent a significant and widespread obstacle to sustainable development, affecting its economic, social, and environmental dimensions. SDS pose severe challenges to achieving several Sustainable Development Goals (SDGs), including the eradication of poverty, the achievement of zero hunger, the improvement of health and well-being, the provision of clean water and sani

Väldigt lite forskning har gjorts om TikTok-användning och uppmärksamhetsförmåga. Denna experimentella studie syftade till att undersöka om TikTok-användning är relaterad till uppmärksamhet mätt både genom självskattning och genom ett prestationsbaserat test, samt om ett kortsiktigt orsakssamband kunde påvisas. Den syftade även till att undersöka sambandet mellan självskattning och prestationstestNot much research has been published on the subject of TikTok use and attentional abilities. This experimental study aimed to investigate whether TikTok use is related to attention, measured with both self-assessment and a performance-based test, as well as whether a short-term causal relationship could be found. The study also aimed to examine the relationship between self-assessment and the perf

The purpose of this study was to understand healthcare counselors' experiences with and attitudes toward working with mindfulness in primary care. Counselors who currently or previously worked with mindfulness shared their perspectives through semi-structured individual interviews. The study reached several main conclusions. Counselors applied mindfulness to a wider range of target groups than

This paper examines the impact of COVID-19 on total net FDI inflows in Lithuania. More specifically, the aim is to fill in the gap that exists in previous research by focusing on the critical assessment of finding explanations behind the deviation of the net FDI inflow patterns during the pandemic. To study the relationship, the quarterly data is collected and a time series analysis has been imple

Spray drying is a widely utilized method for producing protein pharmaceutical powders due to its cost-effectiveness, efficiency, ability to extend shelf life and tailor particle characteristics. These advantages make spray drying an optimal option to produce dry powders suitable for inhalation. Dry powders are extensively used in treating lung diseases primarily due to their increased stability, t

På grund av den framfart som generativ AI visar, ser företag möjligheter att utveckla hela sin marknadsföringsprocess. Den tidigare forskningen poängterar hur stora aktörer möts av olika möjligheter, utmaningar och risker när de använder denna nya teknik. Samtidigt visar forskningen på en positiv framtid för generativ AI i utvecklandet av stora företags marknadsföring. Tidigare forskningslitteratu

This thesis presents an iconographical and comparative study of the “fishing Erotes” motif in Roman mosaics. Previous scholars have overlooked this scene despite its prevalence, and it has not been subjected to a comprehensive investigation. A selection of 15 mosaics from several Mediterranean locations were analyzed using the semiotic model as a theoretical framework and a qualitative approach. T

Uppsatsen ämnar undersöka den svenska asylrättsprocessens förhållande till förbjudna diskretionskrav, förbud som återfinns i svensk och internat-ionell rätt. Detta görs genom ett fokus på rättsfall med förekomst av diskretionsfall samt gällande rätt, utifrån en rättsdogmatisk och rättsanalytisk metod. I Sverige har migration reglerats i egen separat lagstiftning sedan 1914. Som asylsökande har maThis essay aims to examine the relationship between the Swedish asylum process and the absolute prohibition of discretion requirements, prohibitions that are found in Swedish and international law. This is done by focusing on case law where discretion requirements are present and applicable law, using a legal dogmatic and legal analytical method. In Sweden, migration has been regulated by separate