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Uniquely amongst vitamin K-dependent coagulation proteins, protein C interacts via its Gla domain both with a receptor, the endothelial cell protein C receptor (EPCR), and with phospholipids. We have studied naturally occurring and recombinant protein C Gla domain variants for soluble (s)EPCR binding, cell surface activation to activated protein C (APC) by the thrombin-thrombomodulin complex, and
In this paper, we propose a SOC (system-on-chip) test scheduling technique that minimizes the test application time while considering test power limitations and test conflicts. The test power consumption is important to consider since exceeding the system's power limit might damage the system. Our technique takes also into account test conflicts that are due to cross-core testing (testing of inter
Extracts of submerged cultures of a Stereum species afforded four new pentasubstituted phenolic compounds, named hericenols A, B, C, and D (1-4), 6-hydroxymethyl-2,2-dimethylchroman-4-one (5) and the known erinapyrone C. Hericenol A (1) showed weak antimicrobial activity while hericenol C (3) was weakly cytotoxic. The structures of the metabolites were determined by spectroscopic techniques. (C) 2
A thermomechanical model of a porous material is presented. The constitutive model is based on the Gurson model, formulated within a thermodynamic framework and adapted to large deformations. The thermodynamic framework yields a heat equation that naturally includes the mechanical dissipation. To introduce a length scale, the Gurson model was enhanced through non-local effects of the porosity bein
Popular Abstract in Swedish Bildundervisningen i grundskolans tidigare år uppfyller inte de i Sverige uppsatta målen. De nationella utvärderingarna (NU 89) och (NU92) bekräftar detta. Lärarna säger att de saknar ämneskunskaper och utvärderingarna visar att inslag från äldre läroplaner präglar undervisningen. För att ge en bild av hur nuvarande problem kan ha uppstått presenteras i studien en histoThe art education in Swedish primary and secondary schools is far from perfect and as a result pupils seldom reach the desired standard. National evaluations in 1989 and 1992 confirm this. Teachers admit that they lack specific subject knowledge and evaluation reveals that many aspects of older curricula still prevail. The way in which the present problems may have arisen is described through the
A mathematical model has been developed based on the fundamental properties of the control system formed by the lux genes and their products in Vibrio fischeri. The model Clearly demonstrates how the components of this system work together to create two, stable metabolic states corresponding to the expression of the luminescent and non-luminescent phenotypes. It is demonstrated how the cell can "s
Popular Abstract in Swedish Denna avhandling validerar industriella mätsystem, där både de tekniska och mänskliga aspekterna innefattas. Syfte är att få bättre kunskap om den mätteknik som används för att kunna kvalitetsbestämma produkter och för att slutligen på ett mer pålitligt sätt kunna bestämma kvalitén på den tillverkande produkten. För att kunna göra detta föreslårs en metod som tar fram eAlthough there is a fairly large number of books and articles concerning the validation of technical measurement systems, there are only a few which take into account the whole measurement system consisting of both technical and non-technical aspects. A measurement system comprises both the measurement process and the human being who conducts the measurement. In this way, the human being may be a
We analyze cross correlations between price fluctuations of different stocks using methods of random matrix theory (RMT). Using two large databases, we calculate cross-correlation matrices C of returns constructed from (i) 30-min returns of 1000 US stocks for the 2-yr period 1994-1995, (ii) 30-min returns of 881 US stocks for the 2-yr period 1996-1997, and (iii) 1-day returns of 422 US stocks for
Quantitative RT-PCR (QRT-PCR) enables the sensitive and specific detection of mRNA with a small copy number. We used the QRT-PCR method and dual-label analysis of amplification products for the detection of prostate-specific antigen (PSA) mRNA. The QRT-PCR assay employed a PSA-like internal standard (IS) mRNA, which was used to quantify the PSA mRNA copies and to control the variations during the
In this thesis two processes have been modeled and controlled, namely the plate thickness control and the slab temperature control. The classical solution for the thickness control problem can't handle asymmetric hardness variations and the estimation of the controlled output introduces stability problems. A nonlinear multivariable model for the thickness control system is derived. The parameters
The title compound, C18H10N2SSe, is a pentacyclic ring system folded along the S center dot center dot center dot Se vector. The central thiaselenine ring adopts a boat conformation and the two halves of the molecule are related by a crystallographic mirror plane.
En analys av Michael Hanekes konstnärskap, hans berättarteknik och teman.
Greater wax moths (Galleria mellonella L., Pyraloidea) use ultrasound sensitive ears to detect clicking conspecifics and echolocating bats. Pyralid ears have four sensory cells, A14. The audiogram of G. mellonella has best frequency at 60 kHz with a threshold around 47 dB sound pressure level. A1 and A2 have almost equal thresholds in contrast to noctuids and geometrids. A3 responds at + 12 to + 1
