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The effects of 2,3-butanedione monoxime (BDM) were studied in smooth muscle fibres from guinea pig taenia coli. In intact muscle, active force during contractions induced by high-K+ was inhibited by about 10% in 1 mM BDM and by approximately 70% in 10 mM BDM. Intracellular [Ca2+] during contraction, measured with the fura-2 technique, was reduced in the presence of BDM. The reduction in force and

We consider possible schemes for the resonance-enhanced two-photon ionization (RETPI) of Ne and Ar atoms under the action of bichromatic radiation of intense resonance lines of HI, HeI, and HeII in a radiation-rich astrophysical plasma. The ionization rate is comparable to or exceeds the recombination rate in rarified astrophysical plasma, which leads to the accumulation of singly ionized ions wit

Children's mental representations of situations involving another child's distress were examined in two studies. Study 1 examined 3- to 7-year-old children's (n = 44) ideas about what victims and bystanders would think, feel and do in hypothetical situations. In Study 2, 7- to 8-year-olds (n = 40) described their own cognitive response to situations in which they were confronted with another's dis

Exercise during growth and adolescence increases bone mineral density (BMD) in weight-loaded skeletal regions. The development of BMD in unloaded or minimally loaded regions during activity is unclear. We measured BMD in one unloaded, one partly loaded and one highly loaded skeletal region in 67 active soccer players, mean age 22.7 years (range 17-35 years), 128 former soccer players, mean age 54.

We discuss the tunneling between two parallel modulated two-dimensional electron systems in tilted magnetic fields. The electronic states are described in terms of the magnetic crystal momentum, and tunneling events connect the states whose momenta differ by a shift due to the in-plane component of the field. We use this fact to develop a theory of how the features of the artificial two-dimensiona

The generalized hole corrected Debye-Huckel theory (Penfold et al J. Stat. Mech. (2005) P06009) is implemented. Predictions of thermodynamic functions and simple structural properties compare favourably with results from closure of the Ornstein-Zernike integral equation in the mean spherical approximation, and with Monte Carlo simulation of the charged hard sphere primitive model. A strictly nonel

Abstract is not available

The sex- and age-specific incidence has been calculated for ankle fractures from the first part of the 1950s and compared with the 1980s, a 30-year interval. The fractures were also classified according to Lauge-Hansen. Altogether 1784 fractures were found. During that time interval ankle fractures had become more common, particularly those with extensive skeletal involvement, such as the stage IV

Controversy surrounds the impact of atmospheric nitrogen (N) deposition on frost hardiness. There are no specific field studies and the relevance of data from N fertilizer studies is questionable. Field N manipulation experiments with Norway spruce [Picea abies . (L) Karst.] at Skogaby, Sweden, and Sitka spruce [P. sitchensis . (Bong.) Carr.] at Aber in Wales and Deepsyke in Scotland were sampled

OBJECTIVE. To evaluate the recurrence of foot ulcers as well as the cumulative amputation and mortality rates in diabetic patients with previous foot ulcers. DESIGN. A prospective study of consecutively presenting diabetic patients admitted to the Department of Internal Medicine because of foot ulcer with a median follow-up of 4 years. SETTING. A multidisciplinary foot-care team. POPULATION. Five-