Understanding polymorphism in pharmaceutical ingredients is a long-standing challenge in formulation science. A well-known example is paracetamol, C8H9NO2. The marketed stable form I crystallizes with corrugated molecular layers. In contrast, form II, which is thermodynamically favorable at high pressures, has relatively planar layers that can slip over each other without difficulty, but is metast

Background: Despite a decreasing incidence of peptic ulcer disease, most previous studies report a stabile incidence of ulcer complications. We wanted to investigate the incidence of peptic ulcer complications in Sweden before and after the introduction of the proton pump inhibitors (PPI) in 1988 and compare these data to the sales of non-steroid anti-inflammatory drugs ( NSAID) and acetylsalicyli

An article about city fires.

There is a lack of detailed information on the impact of organic feeding regulation on the health and well-being of cows. This has become especially important since January 2008 when the EU required 100% organic ration for organic dairy herds. The aim of this investigation was to determine and compare the levels of essential elements in organic and conventional dairy herds, and to associate them w

Purpose To compare drug treatment changes in older hip fracture patients with and without multi-dose drug dispensing (MDD) after discharge from hospital. Methods Hip fracture patients (aged 65 years or older) for whom the same prescribing procedure was used at discharge and at the 6-month follow-up were extracted from two patient cohorts consecutively recruited in 2008 (n=100) and 2009 (n=99), res

Pseudorapidity gap distributions in proton-proton collisions at root s = 7 TeV are studied using a minimum bias data sample with an integrated luminosity of 7.1 mu b(-1). Cross sections are measured differentially in terms of Delta eta(F), the larger of the pseudorapidity regions extending to the limits of the ATLAS sensitivity, at eta = +/- 4.9, in which no final state particles are produced abov

Allergen-specific immunotherapy (AIT) induces tolerance and shifts the Th2 response towards a regulatory T-cell profile. The underlying mechanisms are not fully understood, but dendritic cells (DC) play a vital role as key regulators of T-cell responses. DCs interact with allergens via Fc receptors (FcRs) and via certain C-type lectin receptors (CLRs), including CD209/DC-SIGN, CD206/MR and Dectin-

Background: A potential dual role of folate in colorectal cancer (CRC) is currently subject to debate. We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within the large European Prospective Investigation into Cancer and Nutrition cohort. Methods: In this nested case-control study, 1,367 incident CRC cases were matched to 2,325 contr

En analys av kvinnors myndighetsansökningar i Sverige under 1800-talet.

The association of Helicobacter pylori with gastroduodenal diseases is well established. The mode of transmission of the organism is still unclear, although the faecal-oral route has been proposed. H. pylori has been detected in gastric antrum, dental plaques, faeces and water. In the light of these studies we attempted to detect H. pylori in antral biopsies, dental plaques, and stool specimens of

Popular Abstract in Swedish I Immi Lundins avhandling Att föra det egna till torgs står 1960-, 1970- och 1980-talen i fokus. Tre kvinnliga författares debutromaner, en från varje decennium, undersöks och sätts i relation till de förändrade positionerna i den offentliga kvinno- och litteraturdebatten under trettioårsperioden. Frågan som avhandlingen söker svar på gäller romanernas samspel med tillkThe Swedish debate both on the role of literature and on the social position of women underwent rapid change during the thirty years from 1960 to 1990. In Bringing the Personal to Market: Narrative, Subject-Matter and Contemporary History in the First Novels of Kerstin Strandberg, Enel Melberg and Eva Adolfsson, the debut novels of three female authors’ are close-read from a thematic and narratolo

The microarchitecture of trabecular bone adapts to its mechanical loading environment according to Wolff's law and alters with age. Trabecular bone is a metabolically active tissue, thus, its molecular composition and microarchitecture may vary between anatomical locations as a result of the local mechanical loading environment. No comprehensive comparison of composition and microarchitecture of t

Nanoscale near-infrared photodetectors are attractive for their potential applications in integrated optoelectronic devices. Here we report the synthesis of GaSb/GaInSb p-n heterojunction semiconductor nanowires for the first time through a controllable chemical vapor deposition (CVD) route. Based on these nanowires, room-temperature, high-performance, near-infrared photodetectors were constructed

Med egna radio- och TV-program, tidningar och sändningar tillgängliga på Internet formar den somaliska gruppen i Minnesota bilden av sig själv. Programmen tas fram genom ideellt arbete och bygger broar mellan kulturer.

This is a critical edition of the correspondence between Queen Victoria of Sweden (1862-1930) and the Bishop and High Preacher to the Court, Gottfrid Billing (1841-1925), together with a commentary situating this surprisingly straightforward correspondence in its political and theological context. Since the queen lived both in the public and the private sphere, she had a ‘mixed’ relation to her sp

A search for new charged massive gauge bosons, called W', is performed with the ATLAS detector at the LHC, in proton-proton collisions at a centre-of-mass energy of root s = 8 TeV, using a dataset corresponding to an integrated luminosity of 20.3 fb(-1). This analysis searches for W' bosons in the W' -> t (b) over tilde decay channel in final states with electrons or muons, using a multivariate me

The purpose of the thesis is to study, through the narratives of women subjected to violence, how men’s violence against women in intimate relationships is accounted for, and how such accounts vary with the type of social relation and context she is in. The specific context in focus here is the legal system, with the police as the first link in the legal chain. The empirical material consists of

Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. Novel treatment strategies are highly needed, as well as increased understanding of the hi