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Role of WT1-ZNF224 interaction in the expression of the tumor suppressor interferon regulatory factor 8 in leukemia cells
Surrogate safety measures and traffic conflict observations.
The chapter primarily focuses on observing traffic conflicts (also known as near-accidents) as a site-based road safety analysis technique. Traffic conflicts are a type of surrogate safety measure. The term surrogate indicates that non-accident-based indicators are used to assess VRU safety instead ofthe more traditional approach focusing on accidents (see chapter 2). The theory underpinning surro
Mechanistic Toxicology : Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization
Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. Traditionally, such risk assessments have been based on animal tests, but due to sever
Agreement between test procedures for the single-leg hop for distance and the single-leg mini squat as measures of lower extremity function
Background: Different test procedures are often used within performance-based measures, causing uncertainty as to whether results can be compared between studies. Thus, the aim of this study was to assess agreement between different test procedures for the single-leg hop for distance (SLHD) and the single-leg mini squat (SLMS), respectively, two commonly used tasks for assessing deficiency in lowe
Implementing handball injury-prevention exercise programs – A practical guideline
Frågeformulär och muskelfunktionstest – vad behövs?
Can we rely on ‘climate-friendly’ consumption?
In policy and research on sustainable consumption in general, and climate-oriented consumption specifically, key questions centre around whether people are motivated and prompted to support such consumption. A common claim in the scholarly debate is that policy makers, in face of fundamental governance challenges, refrain from taking responsibility and instead invest unrealistic hopes in that cons
Knowledge Resistance : How We Avoid Insight from Others
Why do people and groups ignore, deny and resist knowledge about society's many problems? In a world of 'alternative facts', 'fake news' that some believe could be remedied by 'factfulness', the question has never been more pressing. After years of ideologically polarised debates on this topic, the book seeks to further advance our understanding of the phenomenon of knowledge resistance by integra
Samverkan bortom torghandel och elfenbenstorn
Dynamic Thermal Performance and Controllability of Fan Coil Systems
In order to characterize and control a system properly, it is inevitably necessary to understand and define the interactions between various design parameters and the controllability of the system. This study experimentally investigates effects of three design parameters, including supply water temperature, fan speed, and room heat load, on the dynamic response of a fan coil system. The experiment
Validation of TEKNOsim 6 According to CIBSE TM33
TEKNOsim is a simple and user-friendly program for analyzing thermal indoor climate and performing annual hourly simulations. The program was originally developed to calculate heating and cooling demands, and indoor climate conditions of a single zone building for peak winter and summer design days. However, TEKNOsim version 6 has been revised to incorporate several new features including annual e
Storage and Utilization of the Waste Heat from National Veterinary Institute (SVA), Uppsala, Sweden
The incineration furnace at National Veterinary Institute (SVA) in Uppsala, Sweden, generates a large amount of waste heat. Some of this heat is partially recovered and is used for heating one of the main buildings during the furnace operation. However, around 2,000 MWh is wasted annually due to unavailability of any storage system. This work studies in detail four different solutions to utilize t
Breaking the Unbreakable Union: Nationalism, Disintegration and the Soviet Economic Collapse
This paper investigates the effect of prospective secessions on economic integration and growth by examining the break-up of the Soviet Union in the late 1980s and early 1990s. Firstly, I show theoretically how regional elites had an incentive to restrict domestic trade once secession from the Union became possible. Secondly, I show empirically that the increased likelihood of secessions by the Un
Adjusting the Size of Nations: Empirical Determinants of Separatism and the Soviet Breakup
This paper exploits large variation in separatist protests across the 183 provinces of the Soviet Union between 1987 and 1992 to measure the demand for autonomy and secession. This enables an investigation into the theoretical prediction that the incentive to separate should be influenced by the trade-off between the size of the potentially separating jurisdiction and preference heterogeneity. I f
Did an Oil Shock cause the Collapse of the Soviet Economy?
ApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice
AIMS/HYPOTHESIS: Finding new treatment alternatives for individuals with diabetes with severe insulin resistance is highly desired. To identify novel mechanisms that improve glucose uptake in skeletal muscle, independently from insulin levels and signalling, we have explored the therapeutic potential of a short peptide sequence, RG54, derived from apolipoprotein A-I (ApoA-I).METHODS: INS-1E rat cl
Comprehensive modelling study on observed new particle formation at the SORPES station in Nanjing, China
Mass-consumption as an activator of sustainable consumerist potentials
This chapter focuses on the relation between mass-consumption and sustainable consumption.Mass-consumption concerns the omnipresent role of consumption in contemporary societieswith its problems of excessive resource use in current practices of consumption. The latemodern context and forces of mass-consumption can both trigger and prevent sustainableconsumption as well as shape its outcome. Throug
Glycogen metabolism is impaired in the brain of male type 2 diabetic Goto-Kakizaki rats
Diabetes impacts the central nervous system predisposing to cognitive decline. While glucose is the main source of energy fueling the adult brain, brain glycogen is necessary for adequate neuronal function, synaptic plasticity and memory. In this study, we tested the hypothesis that brain glycogen metabolism is impaired in type 2 diabetes (T2D). 13 C magnetic resonance spectroscopy (MRS) during [1