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Health Hazards in Middle-Aged Women with Cardiovascular Disease: A Case-Control Study of Swedish Women. The Women's Health in the Lund Area (WHILA) Study.

Objective: To delineate the health profile in middle-aged women with cardiovascular disease (CVD). Methods: The Women's Health in the Lund Area (WHILA) project covered all women born 1935 - 1945 ( n = 10,766) living in the Lund area; 6917 (64.2%) women completed a generic questionnaire and underwent physical and laboratory assessments. Of the 6917 women, 6416 were postmenopausal women, of whom 104

The role of free and attached microorganisms in the decomposition of estuarine macrophyte detritus

Abundance and respiration of free and attached microorganisms were monitored during the decomposition of the seagrass Scirpus maritimus leaves in laboratory microcosms for 30 days. There was a clear succession between bacteria and heterotrophic flagellates during the course of the study. The beginning of the study (1-4 days) was characterized by higher rates of bacterial respiration, compared to t

Ammoxidation of toluene over molybdenum oxides

The ammoxidation of toluene was studied both in presence and absence of gaseous oxygen over MoO3 and in situ prepared Mo4O11 (orth.) and MoO2. Irrespective of the partial pressure of oxygen, total reaction rates decrease in the following order: MoO3 > Mo4O11 > MoO2. The corresponding sequence for the selectivity towards formation of benzonitrile was found to depend on the partial pressure of oxyge

An enzymatic method for the synthesis of mixed-acid phosphatidylcholine

The enzymatic synthesis of PC with decanoic acid in the sn-1 and hexanoic acid in the sn-2 position is described. The procedure comprises the following enzymatic steps: (i) treatment of egg yolk with phospholipase A(2) (PLA(2)) to hydrolyze egg yolk PC to 1-acyl lysophosphaticlylcholine (LPC) (ii) esterification of I-acyl LPC with hexanoic acid catalyzed by PLA(2) to yield PC with hexanoic acid in

Effects of GH on cognitive function in elderly patients with adult-onset GH deficiency: a placebo-controlled 12-month study

Objective: Young adults with childhood-onset GH deficiency (GHD) have reduced memory and attention, which can be improved by treatment with GH. Little information is available on cognitive function in elderly GHD patients. Design: Single center, double-blind, randomized, placebo-controlled study of 52-week duration. Methods: Elderly GH therapy naive GHD patients (n = 34; age range 60-77 years) wer

Cyclometallated iridium and platinum complexes with noninnocent ligands

The electronic properties of the cyclometalated ((CN)-N-and) complexes of iridium and platinum metals with a catechol ligand have been studied experimentally and computationally. The synthesis and characterization of (p-tolylpyridine)Ir(3,5-di-tert-butylcatechol) (abbreviated Ir-sq) and (2,4-diflorophenylpyridine)Pt(3,5-di-tert-butylcatechol) (abbreviated Pt-sq) are reported along with their struc

Ethanol intake and risk of lung cancer in the European prospective investigation into cancer and nutrition (EPIC)

Within the European Prospective Investigation into Cancer and Nutrition (EPIC), the authors examined the association of ethanol intake at recruitment (1,119 cases) and mean lifelong ethanol intake (887 cases) with lung cancer. Information on baseline and past alcohol consumption, lifetime tobacco smoking, diet, and the anthropometric characteristics of 478,590 participants was collected between 19

Multicast routing for ad hoc networks with a multiclass scheme for quality of service

As multimedia- and group-oriented computing becomes increasingly popular for the users of wireless mobile networks, the importance of features like quality of service (QoS) and multicasting support grows. Ad hoc networks can provide users with the mobility they demand, if efficient QoS multicasting strategies are developed. The ad hoc QoS multicasting (AQM) protocol achieves multicasting efficienc

Intraoperative proximal endoleaks during AAA stent-graft repair: evaluation of risk factors and treatment with Palmaz stents

PURPOSE: To study factors that might contribute to intraoperative proximal type I endoleak and to evaluate the placement of giant Palmaz stents as a therapeutic option. METHODS: Thirty-three patients (30 men; median age 72 years, range 50-85) with abdominal aortic aneurysms underwent implantation of fully supported Gianturco Z-stent-based endografts (12 custom-made aortomonoiliac and 21 bifurcated

Transformation to a customer-oriented perspective through action learning in product and service development

Customer orientation is strongly visible in the visions and strategies of most organizations, but how do these visions and strategies move from intentions to practice? This question provides the focus for this research which aims to acquire deeper insights into this process. The point of departure is the change in perspective from a product to a customer orientation in product and service developi

The influence of personality traits on neuropsychological test performance and self-reported health and social context in women

The relationship between on the one hand personality traits and, on the other hand, neuropsychological test performance, self-rated distress symptoms, psychosocial work exposure, and social interaction patterns, was studied in a group of healthy women (N= 101). All subjects completed the Karolinska Scales of Personality inventory (KSP) and the majority of the subjects (n = 88) completed the State

Geometric scaling and QCD dynamics in DIS

DIS data from HERA show a striking regularity as sigma(gamma*p) is a function of the ratio tau = Q(2)/Q(s)(2)(x) only. The scaling function shows a break at 7 t, which has been taken as an indication for saturation. However, besides saturation also the transition between dominance of k(perpendicular to)-ordered (DGLAP) and k(perpendicular to)-non-ordered (BFKL) evolution contributes to a break aro

A generic surface modification strategy for sensing applications based on Au/SiO2 nanostructures

A generic protocol for the creation of material-mediated self-assembled patterns of streptavidin, defined solely by patterns of gold and SiO2, is presented. Protein-adsorption resistance of selected regions was obtained by material-specific adsorption of thiol-modified poly(ethylene)glycol (thiol-PEG) on gold followed by adsorption of poly-L-lysine (PLL) modified PEG (PLL-g-PEG) on SiO2. Selective

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat

The immunosuppressant drug cyclosporin A (CsA) is considered to be inherently protective in conditions of ischemia, e.g. in hepatic and cardiac tissue. However, investigations of effects of CsA on neuronal tissue have been contradictory, probably because the blood-brain barrier (BBB) is virtually impermeable to CsA. In the present study, we exploited the finding that the insertion of a syringe nee

Cholesterol Dependence of Vascular ERK1/2 Activation and Growth in Response to Stretch. Role of Endothelin-1.

Objective— Stretch-induced growth of the vascular wall plays a role in hypertension and neointima formation. Its signal pathways involve integrins, cytoskeleton, membrane receptors, and ion channels, some of which are organized in cholesterol-rich, membrane domains such as lipid rafts or caveolae. This study tested the role of rafts/caveolae in stretch-induced vascular growth by manipulation of me

Ionic charge, radius, and potential control root/soil concentration ratios of fifty cationic elements in the organic horizon of a beech (Fagus sylvatica) forest podzol

The root/organic soil concentration ratio; R/S) of 50 cationic mineral elements was related to their ionic properties, including ionic radius (r), ionic charge (z), and ionic potential (z/r or z(2)/r). The materials studied were ectomycorrhizal beech (Fagus sylvatica L.) roots and their almost purely organic soil substrate, the O-horizon (mor; raw humus) of a Podzol in South Sweden, developed in a

Effect of SpeB and EndoS from Streptococcus pyogenes on human immunoglobulins

Streptococcus pyogenes secretes a specific immunoglobulin G (IgG)-protease, SpeB, as well as the IgG glycan-hydrolyzing enzyme EndoS. Here we show that SpeB also degrades IgA, IgM, IgD, and IgE. We also show that EndoS only hydrolyzes the glycan moiety on native but not denatured IgG. Thus, SpeB has a broad immunoglobulin-degrading activity, while EndoS is highly specific for IgG.