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The outer membrane protein A (OmpA) family contains an evolutionary conserved domain that links the outer membrane in Gram-negative bacteria to the semi-rigid peptidoglycan (PG) layer. The clinically significant pathogen Pseudomonas aeruginosa carries several OmpA family proteins (OprF, OprL, PA0833, and PA1048) that share the PG-binding domain. These proteins are important for cell morphology, me

Over the past few decades, a significant increase in multi-drug-resistant pathogenic microorganisms has been of great concern and directed the research subject to the challenges that the distribution of resistance genes represent. Globally, high levels of multi-drug resistance represent a significant health threat and there is a growing requirement of rapid, accurate, real-time detection which pla

Feminist Activism in the Post-2010s Sinosphere examines a variety of urgent feminist issues in 21st-century China, including the #MeToo movement, online misogyny, feminism in popular media, and the experiences and rights of queer, trans and ethnic minority groups. The chapters explore shifting dynamics between state feminism, NGO and grassroots movements, the intersection of academia and intellect

BackgroundHalogenated anaesthetic agents are potent greenhouse gases, but little is known about the trajectory of their use and their greenhouse gas impact on a global level. The primary aim of this study was to estimate the global greenhouse gas impact of halogenated anaesthetic agents over the preceding 10 years.

The European Health Data Space (EHDS) marks a pivotal moment in regulating wellness applications within the European Union. This chapter examines the implications of the EHDS for user control over electronic health data processed through wellness apps, scrutinising the regulatory frameworks provided by both the General Data Protection Regulation (GDPR) and the EHDS. Despite the GDPR’s stringent re

Tertiary Lymphoid Structures (TLS) are organized aggregates of immune cells such as T cells, B cells, and Dendritic Cells (DCs), as well as fibroblasts, formed postnatally in response to signals from cytokines and chemokines. Central to the function of TLS are DCs, professional antigen-presenting cells (APCs) that coordinate the adaptive immune response, and which can be classified into different

Promoter region sequences of human and mouse Igk-V genes were aligned and found to be conserved for about 200-300 base pairs (bp) within subgroups/families. No promoter similarity was found between IGKV promoters from different human subgroups. Related mouse Igk-V gene families were conserved in the promoter region but no similarity was evident when promoters from unrelated Igk-V gene families wer

A novel Ets protein was isolated by yeast one-hybrid screening of a cDNA library made from lipopolysaccharide-stimulated mouse splenic B cells, using the SP6 κ promoter κY element as a bait. The novel Ets protein was most closely related to PU.1 and Spi-B within the DNA binding Ets domain and was therefore named Spi-C. However, Spi-C may represent a novel subgroup within the Ets protein family, as

Eye tracking has been used as part of software engineering and computer science research for a long time, and during this time new techniques for machine learning (ML) have emerged. Some of those techniques are applicable to the analysis of eye-tracking data, and to some extent have been applied. However, there is no structured summary available on which ML techniques are used for analysis in diff

Presents a new view of the standard of living development in Sweden during the agricultural revolution, using evidence on the ability to overcome short-term economic stress. The results corroborate previous findings, based on a variety of indicators, that standard of living in Sweden increased for most people after the mid-nineteenth century, but also support a more negative view of the immediate

Sociology of philosophy is the name of a theory-based, empirical sociological subdivision, whose basic approach is praxeological: doing philosophy involves a variety of socially situated practices that in some cases result in philosophical arguments and doctrines fixed in text. Constellation research is an approach developed by the German philosopher Dieter Henrich (1927–2022) for investigations i

Introduction The Universal Declaration of Human Rights includes all categories of human rights in one and the same instrument. The same approach has been followed in many subsequent human rights treaties, including, for example, the Convention on the Rights of the Child (CRC) and the African Charter on Human and Peoples’ Rights (African Charter). However, the two Covenants of 1966 – the Internatio

The aim of this final chapter is to assemble the key insights of the contributions in the book into a comprehensible Nordic approach towards place branding that can be distinguished from other approaches in the field. Nordic place branding is situated conceptually, empirically and epistemologically in the field by offering a manifesto for research in which the peculiarity of the Nordic, as we have

Since 2006, Lebanon’s Shi’i community witnessed significant transformations shaped by Hezbollah’s two promises: to secure the release of detainees in Israeli prisons through armed resistance, and to rebuild and redevelop Dahiya “more beautiful than it was.” In its effort to fulfill its two promises, the party’s socio-urban intervention revealed spaces of compatibility between a political project o

Oil-based drug delivery systems have been studied in different aspects. The present study proposes a new application for an oil-based delivery system, focusing on controlled release until the drug reaches the later part of the small intestine. Bulk surfactants and interfacial surfactants were added into the oil formulation to provide a better mechanistic understating of the lipolysis. Validation o

Follicular dendritic cells (FDCs) are the antigen (Ag)-trapping accessory cells of the germinal centres (GCs), essential for the development of humoral immune responses and memory. FDCs reside in the microenvironment of secondary lymphoid tissue where Ag-activated B cells expand, and undergo isotype switching and affinity maturation prior to becoming memory B cells. In addition to delivering Ag, F

A new immunoassay for the detection of hepatitis C core antigen (HCVcoreAg) in peripheral blood during serological window-phase was evaluated among healthy blood donors, commercially available hepatitis C virus (HCV) seroconversion panels and in-house specimens from individuals undergoing seroconversion. Among 1964 low-risk blood donor samples, seven samples were initially reactive but only one wa

In this publication we have assembled eight case studies and a ”national report” on Sweden that we wrote during 2005 as part of work commissioned by the European Foundation in Dublin. The Foundation had in the 1990’s and in the first years of the 21st century as one of its objectives to investigate the situation for older and ageing workers in Europe, and to develop policy initiatives on the level