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Background: This preclinical study in humans was designed to selectively induce delayed nociceptive pain responses to individually titrated laser stimulation, enabling separate bedside intensity scoring of both immediate and delayed pain. Methods: Forty-four (fourteen female) healthy volunteers were subjected to repeated nociceptive dermal
In this reply to S. Durbin's comment on our original paper "Ultrafast terahertz-field-driven ionic response in ferroelectric BaTiO3," we concur that his final equations 8 and 9 more accurately describe the change in diffracted intensity as a function of Ti displacement. We also provide an alternative derivation based on an ensemble average over unit cells. The conclusions of the paper are unaffect
This article explains perceived loneliness among people in Europe by accounting for cultural factors as well as social isolation. Culturally, it measures the impact of both personal and societal individualism-collectivism on loneliness. It accounts for social isolation by looking at the separate effects of living alone, emotional isolation, and relational isolation. Using a 2014 European Social Su
The mechanism of how patatin-like phospholipase domain-containing protein 3 (PNPLA3) variant M148 is associated with increased risk of development of hepatic steatosis is still debated. Here, we propose a novel role of PNPLA3 as a key player during autophagosome formation in the process of lipophagy. A human hepatocyte cell line, HepG2 cells, expressing recombinant I148 or 148M, was used to study
Postprandial glycemic and insulinemic responses to variously processed red kidney beans were evaluated in normal subjects. The dried seeds were (a) boiled; (b) autoclaved; (c) boiled, freeze-dried, and milled to obtain a precooked flour (PCF) rich in cell-enclosed starch; or (d) milled, steam-cooked, and freezedried to yield a flour containing free starch (FSF). All bean products elicited lower me
OBJECTIVES. In clinical studies, it has been found that treating asthmatic patients with inhaled corticosteroids can reduce the need for in-patient care. The purpose of this study was to determine if such a relationship could be observed in available health-care statistics in Sweden and, if such a relationship could be established, what health economic consequences it implied. METHODS. A retrospec
Background: Chronological age is a key clinical determinant ofaortic stiffness. Self-perceived age (SPA) is a strong predictor ofwell-being and long-term health. We aimed to investigate theassociation between SPA, chronological age, and aortic stiffness(vascular ageing) in the general population.Methods: Cross-sectional analysis of a population-based study,Malmö Offspring Study (n=3563). Mean age
Purpose: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Despite the best available treatment, prognosis remains poor. Current standard therapy consists of surgical removal of the tumor followed by radiotherapy and chemotherapy with the alkylating agent temozolomide (TMZ). Experimental studies suggest that antisecretory factor (AF), an endogenous protein with propose
For two-component composites, we address the inverse problem of estimating the structural parameters and decrease measurement errors in bulk property measurements. A measurement of the effective permittivity at one frequency gives microstructural information about the composite that is used in cross-property bounds to estimate the effective permittivity at other frequencies. We use this informatio
We train and compare the performance of two machine learning methods, a multi-variate regression network and a ResNet-50-based neural network, to learn and forecast plant biomass as well as the relative growth rate from a short sequence of temporal images from plants in aeroponic cultivation. The training dataset consists of images of 57 plants taken from two different angles every hour during a 5
Men who sell sex to other men are still an under-researched area of study, despite their long presence in our history. But those who are selling sex in the 21st Century have new and peculiar characteristics. This paper highlights the presence of the so-called middle-class, men with high educational credentials that have decided to engage in sex working. Moreover, indulging in the encounter itself
Photovoice is an increasingly popular research method across disciplines due to its flexibility and capacity for generating rich data. This article argues that while its practical virtues are abundant, the theoretical contributions of photovoice to qualitative research are just as important. We argue that photographs can act as boundary objects that enable collective sensemaking at multiple stages
This study examines jaw and lip aperture characteristics of syllables. High correlations were found between velocity and displacement of opening/closing of lips and jaw, similar to previous studies. However, lip aperture opening velocity changed as a function of manner and voicing of syllable onset while jaw opening velocity, except for a plosive onset, did not change. In addition, differences wer
There has not been a satisfying numerical validation of the theory of effective waves in random particulate materials. Validation has been challenging because the theoretical methods for effective waves have been limited to random particulate media in infinite slabs or half-spaces, which require a very large number of particles to perform accurate numerical simulations. This paper offers a solutio
The aim of the article is to correlate grey and white matter changes and their topography to the results of modern methods for brain imaging such as CT, rCBF, PET, SPECT and NMR in Alzheimer's type of dementia. The findings are based on the study of a large material investigated thoroughly patho-anatomically. The findings are correlated with psychiatric and neurophysiologic follow-up studies. The
BACKGROUND: Pragmatic language is key for adaptive communication, but often compromised in neurodevelopmental conditions such as autism spectrum disorder (ASD). Decontextualized language-to talk about events and things beyond here and now-develops early in childhood and can be seen as a pre-pragmatic ability. Little is known about the factors that contribute to decontextualized language use in tod
16S-bacterial data have been examined to evaluate the microbial community in ocean sediment along the coast of Helsingborg. Routine measurements of Escherichia coli (E. coli) in waters near recreational beaches in Helsingborg have been above the safe limit during several summers, even during dry conditions (such was the case in summer 2018). Stormwater, which previously have been the suspected mai
