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Purpose: In Parkinson’s disease (PD), pathological microstructural changes occur that may be detected using diffusion magnetic resonance imaging (dMRI). However, there are few longitudinal studies that explore the effect of disease progression on diffusion indices. Methods: We prospectively included 76 patients with PD and 38 healthy controls (HC), all of whom underwent diffusion kurtosis imaging
The role of CD4+ T cells in atherosclerosis has been shown to be dependent on cytokine cues that regulate lineage commitment into mature T helper sub-sets. In this study, we tested the roles of IL-1R1 and MyD88 signalling in CD4+ T cells in atherosclerosis. Methods and results We transferred apoe-/-myd88\+/\+ or apoe-/-myd88-/- CD4+ T cells to T-A nd B-cell-deficient rag1-/-apoe-/- mice fed high f
Human Rights Cubed? Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights International Humanitarian La
https://rwi.lu.se/2016/08/26/human-rights-cubed/ - 2026-09-18
A policy entrepreneur is a distinct political actor aiming to affect change. The theoretical narrative regarding policy entrepreneurs is underpinned by their commitment to a policy solution, the multi-dimensional strategies they use to promote that solution, and a suite of attributes and skills facilitating their actions. Policy entrepreneurs reveal themselves through their attempts to transform p
Cardiovascular autonomic dysfunction (CVAD) is a malfunction of the cardiovascular system caused by deranged autonomic control of circulatory homeostasis. CVAD is an important component of post-COVID-19 syndrome, also termed long COVID, and might affect one-third of highly symptomatic patients with COVID-19. The effects of CVAD can be seen at both the whole-body level, with impairment of heart rat
Factors behind intraspecific variation in sensitivity to pathogens remain poorly understood. We investigated how geographical origin in two North European amphibians affects tolerance to infection by the chytrid fungus Batrachochytrium dendrobatidis (Bd), a generalist pathogen which has caused amphibian population declines worldwide. We exposed newly metamorphosed individuals of moor frog Rana arv
När den första hovrätten inrättades i Sverige år 1614 gavs den bland annat i uppdrag att kontrollera de dödsdomar som utdömts i underrätterna. Då en ny och strängare strafflag, kallad Appendix, införts 1608 hade antalet dödsdomar ökat kraftigt. Hovrätten kunde då välja att antingen fastställa underrättens dödsdom, eller leuterera och utdöma ett eget straff. När hovrätten utdömde ett annat straff ä
Barn som berörs av avhysning ställs i likhet med barn som drabbas av utmätning av bostad inför risken att förlora sitt hem. En trygg hemmiljö anses vara av stor vikt för barnets utveckling och främja behovet av stabilitet. Barn som befinner sig i osäkra beroendesituationer riskerar att påverkas negativt på flera plan, och upplever inte sällan stark oro och försämrat psykiskt mående. I denna uppsChildren who are affected by an eviction are, like children affected by attachment and sale of a house due to enforceable debt, faced with the risk of losing their home. A safe home environment is considered to be of great importance for the child's development and promotes the need for stability. Studies show that children subject to unsettled housing situations tend to experience grave anxie
The development of Mälaräng in the southwestern part of Stockholm aims to bridge the social and economic gap in between neighboring areas Mälarhöjden and Bredäng. Theories of the Just City by Susan Fainstein and the Lively City constructed by Jane Jacobs are applied to investigate the planning of Mälaräng regarding social, economic and physical environment-factors through the lens of justice and l
Entrepreneurial agency theory has been designated as an important field of research within the corporate entrepreneurial context. When ownership structures in well-established corporations change, certain agitation can result. These ownership changes can subsequently influence entrepreneurial agency in such ventures. As a change of ownership in small to medium-sized enterprises (SMEs) has an even
The number of diplomatic actors that use social media platforms to communicate with the publics has increased in the past years. Yet, these communicative approaches are still poorly researched. Moreover, the few studies from diplomacy and the ones from communication that explore two-way communication on social media present contradictions. If scholars from diplomacy present dialogue as a taken for
Behovet av avancerad rening genom till exempel ozonering eller aktivt kol på avloppsrenings-verk blir tydligare i världen som följd av höga uppmätta nivåer av läkemedelsrester i recipienter. I länder som Schweiz är implementeringen redan idag lagstadgad och också i Sverige förväntas inom en överskådlig framtid krav införas på avlägsning av organiska mikroföreoreningar från avloppsvatten. I dagsläg
This study aims to investigate the ecological sustainability of different beverage packaging and compare this to consumers’ perception of the most environmentally friendly packaging type. A literature analysis was made to understand the advantages and disadvantages of different packaging as well as consumer behavior from other surveys in other studies. Lastly this study conducted and preformed its
Individers förhållningssätt och tillfredsställelse rörande sin sexualitet har visat sig hänga nära samman med upplevt mående och hälsa. Äldre kvinnors upplevelse av sin sexualitet är ett relativt outforskat område, speciellt i en svensk kontext. Mot bakgrund av detta var syftet med denna studie att skapa en fördjupad förståelse och kunskap kring 65-80 åriga kvinnors upplevelse av sexualitet och se
Trauma i barndomen har en betydande inverkan på livslång fysisk och mental hälsa samt utveckling. Tidiga interventioner stärker barnets motståndskraft och mildrar traumans långsiktiga effekter på välbefinnandet. En sådan intervention går ut på att utbilda viktiga vuxna i barnets omgivning för att skapa en gynnsam miljö. Traumamedveten omsorg (TMO) är en intervention som erbjuds som ett utbildnings
