Background: Variation in the 10 toll-like receptor (TLR) genes has been significantly associated with allergic rhinitis (AR) in several candidate gene studies and three large genome-wide association studies. These have all investigated common variants, but no investigations for rare variants (MAF≤1%) have been made in AR. The present study aims to describe the genetic variation of the promoter and

BACKGROUND: Patients with back and neck pain are often seen in primary care and it is important to provide them with tailored interventions based on risk stratification/triage. The STarT Back Screening Tool (SBT) is a widely used screening questionnaire which has not yet been validated for a population with back and/or neck pain with short duration. Our aim was to compare the concurrent validity o

The main challenge for future electricity systems is to match the available electricity from variable renewable resources with the electricity demand in place, time and quantity. One option for increasing electricity system flexibility is to integrate the electricity system with the district heating systems via the use of power-to-heat technologies such as electric boilers. The overarching objecti

Heavy combined lung weight at autopsy is a non-specific autopsy finding associated with certain causes of death such as intoxication. There is however no clear definition of what constitutes "heavy" lung weight. Different reference values have been suggested but previous studies have been limited by small select populations and only univariate regression has been attempted. The aim of this study w

ackground: The separate spheres, in which men dominate the public sphere of politics, arts, media, and wage work and women dominate the private sphere of unpaid production and caring, is a powerful configuration in much social theory (including Parsons, Becker, and Goode), which posited that with industrialization, family structures and activities would converge towards the nuclear family with strBackground: The separate spheres, in which men dominate the public sphere of politics, arts, media, and wage work and women dominate the private sphere of unpaid production and caring, is a powerful configuration in much social theory (including Parsons, Becker, and Goode), which posited that with industrialization, family structures and activities would converge towards the nuclear family with st

A 1561-year tree-ring width (TRW) chronology covering the period 2668–1108 BC (4617–3057 BP) has been developed from 159 moisture-sensitive peatland pines (Pinus sylvestris L.) sampled at Åbuamossen, southern Sweden. Tree population dynamics and annual growth responses of the trees were shown to reflect and give absolute age to regional hydro-climatological changes. The main wet-shifts recorded in

Background: Early-life physical fitness has rarely been examined in relation to type 2 diabetes mellitus (DM) in adulthood because of the lengthy follow-up required. Elucidation of modifiable risk factors at young ages may help facilitate earlier and more effective interventions. Objective: To examine aerobic capacity and muscle strength at age 18 years in relation to risk for type 2 DM in adultho

Background: Knowledge about social determinants of health has influenced global health strategies, including early childhood interventions. Some psychosocial circumstances - such as poverty, parental mental health problems, abuse and partner violence - increase the risk of child maltreatment and neglect. Healthcare professionals' awareness of psychosocial issues is of special interest, since they

Aerosol particles exist in the atmosphere in large concentrations and have significant global climate effects. New particle formation is an aerosol particle source and, to date, its contribution to the total aerosol concentration in the atmosphere is not fully understood. This study focuses on the extension of new particle formation events that begin in Lille Valby, Denmark and travel over 70 km t

The Linked Data approach in data publishing allows the users and their data-driven applications to have broader use cases which encompass various data sources, either publicly available on the Web, or in private repositories. The use of W3C standards in publishing such data enables uniform access across platforms. Transport information today has higher importance to the citizens and society than e

Background Breast-conserving surgery (BCS) followed by radiotherapy (RT) is an established treatment for women with T1-2N0 breast cancers. Since subgroups of patients have low ipsilateral breast tumour recurrence (IBTR) rates, it is important to study whether RT is necessary for all patients. Patients and methods A total of 1187 women with primary T1-2N0M0 breast cancer were randomised, after stan