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Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. Dysfunctional telomeres are implicated in many complex cellul
Drawing substantially on epistemologies developed in the context of vulnerable populations and responding to calls for greater epistemic justice in marketing research, an intersectional framework involving positionality, partiality, reflexivity, and situated knowledges is proposed to reflect on undertaking market research with Muslim minority populations in non-Muslim majority countries. This popu
The purpose of this study was to establish an experimental setting and an anesthetic method compatible with future sequential studies using (18)F-FDG-PET single scans, i.e. autoradiographic measurements, for the estimation of metabolic rate of glucose (MRglc) in mice. In this study we had no access to a small animal PET scanner and therefore focus was on the anesthetic setting and optimization of
Transport and mobility systems need to be transformed to meet climate change goals and reduce negative environmental and social effects. Despite EU policies having targeted such problems for more than three decades, transitions have been slow and geographically uneven. For effective change to happen, transport and mobility research needs fresh perspectives and better integration of knowledge from
Popular Abstract in Swedish Läpp- käk- gomspalt (LKG-spalt) förekommer hos cirka 200 nyfödda barn per år i Sverige. Det finns idag inte belägg för någon specifik faktor som orsakar LKG-spalten. Utan en adekvat habilitering som bl.a. innehåller kirurgi, tandreglering och talbehandling skulle barnen få funktionella och utseendemässiga problem som skulle leda till en försämrad livskvalite. UtvecklinBody dimensions of 2,936 newborns with cleft lip/palate (CLP) were compared with 2,031,140 singleton newborns between 1973 to 1992. The risk of cleft development was found to be associated with intra-uterine growth retardation - the more severe the cleft, the stronger the association. As digital photography is being increasingly applied in clinical medicine, we devised a computer software program
Neural transplantation is a potential therapeutic method for Parkinson’s disease (PD). Fetal dopaminergic (DA) neurons have been important transplantation cell sources in the history of replacement therapy for PD. Several decades of preclinical animal experiments and clinical trials using fetal DA neuron transplantation in PD therapy have shown not only promising results but also problems. In orde
Purpose: Contemporary firms are increasingly focusing on enhancing the customer experience (CX) to gain a sustainable competitive advantage. However, despite the rapid growth of CX research from both the customer's and the firm's perspectives, the intellectual structure of CX research remains tenuous, thus requiring further investigation. Addressing this gap, the authors review and map the existin
Hållbarhetsforums styrgrupp har det övergripande ansvaret för verksamhetens inriktning och det finns en representant från varje fakultet. Ledamöterna fungerar som kontaktlänk till fakulteterna och som ett systematiskt beslutsstöd för linjeorganisationen i hållbarhetsrelaterade frågor. Styrgruppen är referensgrupp för universitetets miljöchef när det gäller strategiska frågor om universitetets inte
https://www.hallbarhet.lu.se/om-hallbarhetsforum/hallbarhetsforums-styrgrupp - 2026-09-19
Background and Purpose – In the last two decades, enterprise architecture (EA) has become a common approach for the management of information systems in organizations. However, the academic development of the field has not paralleled this turn of events. There is considerable divergence among researchers as to the very definition of EA. The present project seeks to clarify the concepts of EA, draw
My own privilege as an observer of the Palaeolithic and Mesolithic rests on the power of an outsider by wearing lenses from other archaeological research fields. As far as I understand doing archaeology, a reflexive consciousness about the production of knowledge and the communication strategies is fundamental for increasing our knowledge and using our knowledge of the past. The awareness of subje
Evidence-based medicine (EBM) uses the current best evidence to inform decisions about care of individual patients, healthcare procedures, and technologies. The "gold standard" for optimal evidence in the Cochrane system is Level I randomized, controlled trials (RCTs) and meta-analyses of several RCTs. In order to achieve this level of evidence, one of the most important measures is the use of out
Neurological disorders are listed as the second leading cause of death worldwide. Stroke and Alzheimer’s disease (AD) are the major contributors to neurological disorders of deaths. Every year, around 14 million new people are affected by stoke and nearly 10 million new cases of AD are diagonosed worldwide. The number of deaths and disabilities due to these disorders have increased considerably.
Characterization of gene expression in pancreatic islets and its alteration in type 2 diabetes (T2D) are vital in understanding islet function and T2D pathogenesis. We leveraged RNA sequencing and genome-wide genotyping in islets from 188 donors to create the Islet Gene View (IGW) platform to make this information easily accessible to the scientific community. Expression data were related to islet
Popular Abstract in English Zirconium alloys are widely used in nuclear power reactors as cladding material for their fuels due to the high strength, good corrosion resistance and low neutron absorption cross-section, even in extreme environment, that is characteristic for zirconium. The element, however, also has strong affinity for hydrogen, and when both are present they readily react and form Zirconium alloys are widely used in the nuclear industry because of their high strength, good corrosion resistance and low neutron absorption cross-section. Zirconium has a strong affinity for hydrogen, however, and if hydrogen concentration builds up, the material will gradually degrade. In one class of such hydrogen caused degradation, called hydride induced embrittlement, hydrogen chemically re
We describe factors to consider when establishing collaborative research projects with agricultural growers, issues that can arise in establishing these relationships, and key steps that researchers can take to improve collaborations and increase the likelihood of project success. We conclude that the most important features of successful collaborations between researchers and agricultural coopera
