Filtyp
The aim of this thesis project is to evaluate the performance of cylindrical diffuser fibers in IPDT. Spectracure AB has developed a system for real time monitoring of dose parameters during IPDT treatment of prostate cancer using bare-end fiber tips. One of the parameters that is monitored is the effective attenuation coefficient, mu_{eff}, and the goal of this thesis is to study how well this pa
The use of radio-labeled somatostatin analogs, such as 177Lu-labelled DOTATATE, in PRRT, has based on the studies performed until now, shown to be promising for RNT disseminated neuroendocrine tumors [1]. In this regard, the aim of treatment is to assure the delivery of the highest possible absorbed dose to the tumor cells, while saving the normal tissues [1], meaning, to achieve a higher activity
Many high spin rotational bands in superdeformed nuclei have been found in the A ~ 140-150 region, but so far no linking transitions to known normal-deformed states have been found in these nuclei. Therefore, configuration and spin assignments have to be based on indirect spectroscopic information. Identical bands were first discovered in this region of superdeformed shapes. At present, som
Popular Abstract in Swedish Bröd har varit ett av våra viktigaste baslivsmedel sedan antiken (700 f.Kr. – 400 e.Kr.) och kommer med all sannolikhet också fortsätta att vara en viktig del av vår föda även i framtiden. Det i Sverige rekommenderade dagliga intaget (RDI) av kostfiber är 25-35g. Utav dessa kostfibrer bör hälften komma från bröd (33%) och andra spannmålsprodukter (17%), vilket motsvararBread products are one of the most common and important foods in our daily diet, and have been since ancient times. Although it has a long history and comes in many variations, the staling phenomenon of bread is still not fully known. Staling is a complex phenomenon that includes all the physical and sensorial changes occurring in bread during storage. To gain a better understanding of staling, di
The isolation and characterization of six human cysteine proteinase inhibitors is reported. Their distribution in human biological fluids is also described and discussed with respect to physiological function. Studies on kininogen and cystatin C with respect to structure-function relationships and, as a result of the cystatin C studies, a general model for the mechanism of cysteine proteinase inhi
A fully coupled computational fluid dynamics (CFD) approach based on the finite element method, in two-dimensions, is developed to describe a solid oxide fuel cell (SOFC). Both hydrogen and carbon monoxide are considered as electrochemical reactants within the anode. The dimensionless number of electrochemical active sites (EAS), the pore radius (indirectly proportional to the particle radius) and
Presents a method to use linear analysis to capture the frequency coupling of nonlinear and time-varying components. System stability is analyzed by connecting the harmonic transfer functions of the different component models. This facilitates an object-oriented approach to modeling, which supports reuse of models. An analysis of the complete railway system is, of course, difficult. Several locomo
Radionuclide therapy aims to treat malignant diseases by systemic administration of radiopharmaceuticals, often using carrier molecules such as peptides and antibodies. The radionuclides used emit electrons or alpha particles as a consequence of radioactive decay, thus leading to local energy deposition. Administration to individual patients can be tailored with regards to the risk of toxicity in
Three-dimensional compaction simulations of geometries with circular and quadratic cross-sections are reported using dilatant viscoplastic material models representing a ductile steel powder. The simulations are compared with experiments using in situ measurements of the wall-tractions within the die. Two different porous viscoplastic material models have been used: the combined Fleck-Kuhn-MeMeeki
Vegetation fire is one of the naturally occurring disturbances within the Earth system, changing vegetation dynamics and modulating carbon storage in the terrestrial biosphere. While fires are essential to many ecosystems, fire dynamics have been increasingly shaped by human actions since the late eighteenth century. The main drivers behind those changes are climate change and direct human activit
Risk Factors For Coronary Artery DiseaseEpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseasesSleep duration is associated with healthy diet scores and meal patterns: results from the population-based EpiHealth studyBoth Weight at Age 20 and Weight Gain Have an Impact on Sleep Disturbances Later in Life: Results of t
https://www.epihealth.lu.se/kohort/publikationer - 2026-09-09
Head: Karin Stenkula My research group is focused on experimental cell biology research within the diabetes and obesity field. The overall purpose of our research is to explore both normal adipose cell function and the cellular mechanisms causing impaired glucose- and lipid metabolism associated with insulin resistance and type 2 diabetes. At a single cell level, we have shown that the GLUT4 trans
https://www.ludc.lu.se/glucose-transport-and-protein-trafficking - 2026-09-09
Wildfires are a major driver of ecosystem development and contributor to carbon emissions in boreal forests. We analyzed the contribution of fires of different fire size classes to the total burned area and suggest a novel fire characteristic, the characteristic fire size, i.e., the fire size class with the highest contribution to the burned area, its relation to bioclimatic conditions, and intra-
This study investigated the dosimetric impact of uncompensated motion and motion compensation with dynamic multileaf collimator (DMLC) tracking for prostate intensity modulated arc therapy. Two treatment approaches were investigated; a conventional approach with a uniform radiation dose to the target volume and an intraprostatic lesion (IPL) boosted approach with an increased dose to a subvolume o
Identifying operational losses in irrigation canals can be difficult due to inaccurate simplification in designing and operating national guidelines. However, this study aims to provide a practical solution to this problem by identifying operational losses, which are the primary cause of off-farm irrigation water losses. The method involves simulating the daily delivered water to individual Irriga
Popular Abstract in Swedish Människans arvsmassa består av DNA. DNA i sin tur består av nukleotiderna A, T, G och C som i olika kombinationer bygger upp våra gener. Människans "genom" (hela arvsmassa) består av uppåt 100 000 gener och varje gen kodar för ett protein som i sin tur är byggstenarna i våra kroppar. Eftersom DNA är en oerhört lång molekyl och cellerna är väldigt små (ca 10 micrometer) Chromosomal translocations commonly result in the production of fusion genes and the fusion genes are often tumor-type specific. In myxoid and round cell liposarcomas (MLS/RCLS), almost 95% of the cases carry a t(12;16)(q13;p11). In the remaining 5% of the MLS/RCLS tumors, another translocation and fusion gene can be found, i.e. the t(12;22)(q13;q12). These translocations fuse CHOP on chromosome 1
Popular Abstract in Swedish I kopplingsanalys, eller i en något mera generell mening vid genletning, så söker man efter sjukdomsgener längs ett genom. Här kan man tolka ett genom som en mängd av hela, eller bitar av, olika kromosomer. Med avseende på en mängd sammanhängande flergenerationella släkter så observerar man då, längs genomets kromosombitar, markördata, dvs genotyper bestående av nedärvdIn linkage analysis or, in a wider sense, gene mapping one searches for disease loci along a genome. This is done by observing so called marker genotypes (alleles) and phenotypes (affecteds/unaffecteds) of a pedigree set, i.e. a set of multigenerational families, in order to locate the loci corresponding to the underlying disease genes or, at least, to narrow down the interesting genome regions. I
Idiopathic osteoporosis (IOP) in children is characterized by fragility fractures and/or low bone mineral density in otherwise healthy individuals. The aim of the present work was to measure bone mineralization density distribution (BMDD) based on quantitative backscattered electron imaging (qBEI) in children with suspected IOP. Entire cross-sectional areas of transiliac bone biopsy samples from c
Det finns ett behov av frågeformulär som dimensionellt mäter psykiskt fungerande hos ungdomar. Den korta versionen av Extended Strengths and Weaknesses Assessment of Normal Behavior (E-SWAN-G) är designat för att mäta centrala förmågor längs kontinuum från stora svårigheter till stora styrkor. Syftet med denna studie var att genomföra en initial psykometrisk utvärdering av E-SWAN-G kortversion medThere is a need for questionnaires that dimensionally assess psychological functioning in adolescents. The short version of the Extended Strengths and Weaknesses Assessment of Normal Behavior (E-SWAN-G) is designed to assess core abilities along continua from severe weaknesses to great strengths. The aim of this study was to conduct an initial psychometric evaluation of the E-SWAN-G short version
