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UNLABELLED: The aim of this systemic review and meta-analysis was to examine the differences in caesarean section rates across European regions and at a country level by utilizing the Robson classification system. The study has compared caesarean rates across European regions using the Robson classification to identify the drivers of caesarean section use. This review shows significant variations
The complexity and dynamicity of microservice architectures in cloud environments present substantial challenges to the reliability and availability of the services built on these architectures. Therefore, effective anomaly detection is crucial to prevent impending failures and resolve them promptly. Distributed data analysis techniques based on machine learning (ML) have recently gained attentionThe complexity and dynamicity of microservice architectures in cloud environments present substantial challenges to the reliability and availability of the services built on these architectures. Therefore, effective anomaly detection is crucial to prevent impending failures and resolve them promptly. Distributed data analysis techniques based on machine learning (ML) have recently gained attention
The interaction between a low angle grain boundary in front of a crack tip and the emerging plasticity from the tip of a microstructurally short edge crack subjected to fatigue loading has been studied. The modeling rests solely on discrete dislocations, were the geometry is described by dislocation dipole elements in a boundary element approach and the plasticity, restricted to one slip plane, to
This theoretical paper adopts a procedural perspective to identify the challenges associated with the implementation of the full scope of approaches to circular public procurement (CPP). We contend that beyond considering CPP from a substantive standpoint (i.e. the procurement affects outside of the organization), adopting a procedural perspective (i.e. the procurement affects inside an organizati
To counteract global food safety hazards related to raw consumption of ready-to-eat leafy vegetables, a method to improve bacterial status using antagonistic bacteria was studied under field conditions. This is the first study to identify potential Escherichia coli antagonists from the native microbiota on leafy green vegetables and evaluate their effect in an industrial field production setting.
The 2015 Paris Agreement aims to strengthen the global response to climate change, and to maintain an average global temperature well below 2°C, with aspirations toward 1.5°C, by means of balancing sources and sinks of greenhouse gas emissions. Following this, the importance of carbon dioxide removal in global emission pathways has been further emphasized, and Negative Emissions Technologies (NETs
PCR of TCR/Ig gene rearrangements is considered the method of choice for minimal residual disease (MRD) quantification in BCP-ALL, but flow cytometry analysis of leukemia-associated immunophenotypes (FCM-MRD) is faster and biologically more informative. FCM-MRD performed in 18 laboratories across seven countries was used for risk stratification of 1487 patients with BCP-ALL enrolled in the NOPHO A
To explore the availability and accessibility of medically assisted reproduction (MAR) for people living with HIV in Europe, including the feasibility of cross-border care. Methods: We used a polymorphous engagement approach, primarily based on digital and email-based interviews with representatives of national HIV organizations, clinical researchers (infectious disease and/or infertility speciali
Background: Accurate markers for prostate cancer (PC) risk stratification could aid decision-making for initial management strategies. The 4Kscore has an undefined role in predicting outcomes after radical prostatectomy (RP). Methods: We included 1476 patients with 4Kscore measured prior to RP at two institutions. The 4Kscore was assessed for prediction of adverse pathology at RP and biochemical r
Transplantation in Parkinson's disease using human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons is a promising future treatment option. However, many of the mechanisms that govern their differentiation, maturation, and integration into the host circuitry remain elusive. Here, we engrafted hESCs differentiated toward a ventral midbrain DA phenotype into the midbrain of a preclinical
Technical developments for the detection of formaldehyde using laser-induced fluorescence were presented. A technique for simultaneous detection of formaldehyde and OH using one laser system was presented. The combined formaldehyde and OH technique was applied in laboratory flames and a small spark-ignition engine. The iodine measurement was performed in a cell using the second harmonic of the sin
Nanocomposites, formed by incorporating nanoparticles into a matrix of standard materials, are increasing on the market. Little focus has been directed towards safe disposal and recycling of these new materials even though the disposal has been identified as a phase of the products' life cycle with a high risk of uncontrolled emissions of nanomaterials. In this study, we investigate if the carbon
BackgroundHome care is beset with work environment issues and high staff turnover, while research concerned with interventions to improve the work environment is sparse. Few of the existing interventions apply a participative approach, despite this being associated with more positive outcomes and sustainable change. This paper presents a framework, rooted in action research and action learning, fo
Colon capsule endoscopy as an alternative to colonoscopy for the diagnosis of colonic disease may serve as a less invasive and more tolerable investigation for patients. Our aim was to examine patient-reported outcomes for colon capsule endoscopy compared to conventional optical colonoscopy including preference of investigation modality, tolerability and adverse events. A systematic literature sea
Purpose: The authors intend to assess the village health sanitation and nutrition committees (VHSNC) on six parameters, including their formation, composition, meeting frequencies, activities, supervisory mechanisms and funds receipt and expenditures across nine districts of the three states of India. Design/methodology/approach: The cross-sectional study, conducted in the states of Uttar Pradesh
BACKGROUND: The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after treatment in women with early-stage, estrogen-receptor (ER)-positive breast cancer. Extending such therapy beyond 5 years offers further protection but has additional side effects. Obtaining data on the absolute risk of subsequent distant recurrence if therapy stops at 5 years co
In global cities, the impacts of gentrification on the lives and well-being of socially vulnerable residents have occupied political agendas. Yet to date, research on how gentrification affects a multiplicity of health outcomes has remained scarce. While much of the nascent quantitative research helps to identify associations between gentrification and determined health outcomes, it tends to draw
Importance: Hypochondriasis, also known as health anxiety disorder, is a prevalent, yet underdiagnosed psychiatric disorder characterized by persistent preoccupation about having serious and progressive physical disorders. The risk of mortality among individuals with hypochondriasis is unknown. Objective: To investigate all-cause and cause-specific mortality among a large cohort of individuals wit
BACKGROUND: Medication discrepancies in care transitions and medication non-adherence are problematic. Few interventions consider the entire process, from the hospital to the patient's medication use at home.AIM: In preparation for randomised controlled trials (RCTs), this study aimed (1) to investigate the feasibility of recruitment and retention of patients, and data collection to reduce medicat
