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Structural rearrangements of chromosome 8 are frequently encountered in squamous cell carcinomas of the head and neck (HNSCC). These aberrations often affect the centromeric region, resulting in the formation of isochromosome i(8q) and whole arm translocations. Some tumors may display structural rearrangements of 8p23. To characterize further the localization of the breakpoints in such rearrangeme

A crucial requirement in the development of liquid-metal spallation neutron target is knowledge of the composition and amount of volatile radionuclides that are released from the target during operation. It is also important to know the total amount produced, which could be released if there was an accident. One type is the lead-bismuth eutectic (LBE) target where different radionuclides can be pr

High-palaeolatitude plesiosaur, mosasaur and, more rarely, dinosaur fossils are well known from the Maungataniwha Sandstone Member of the Tahora Formation in Mangahouanga Stream, Hawkes Bay, New Zealand. A palynological investigation of strata exposed along Mangahouanga Stream and of transported boulders hosting vertebrate fossils reveals well-preserved assemblages dominated by terrestrial pollen

The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in translational research. This is particularly the case for the validation of protein biomarkers; the lack of accurate, reproducible, and sensitive assays for most proteins has precluded the systematic assessment of hundreds of potential marker proteins described in the literature. Here, we describe a high-through

Aim of the study: Quality of cardiopulmonary resuscitation (CPR) is a critical determinant of outcome following out-of-hospital cardiac arrest. The aim of our study was to evaluate the quality of CPR provided by emergency medical service providers (Basic Life Support (BLS) capability) and emergency medical service providers assisted by paramedics, nurse anesthetists or physician-manned ambulances

The aim of this study was to assess the psychometric properties of a Swedish version of the General Self-Efficacy Scale (GSE) in stroke survivors. The GSE was administered by the same assessor on two occasions 3 weeks apart with 34 stroke survivors (21 men, 13 women; mean age=68.1 years) 6-10 months after stroke. Psychometric properties including targeting and scaling assumptions, and several reli

Background: Several melanoma susceptibility genes have been identified. As part of the international genetic research programme of the GenoMEL consortiums research on genetic mutations in melanoma families, the aim of this study was to examine family members' views about their risk of melanoma, gene testing and genetic research. Methods: Self-report data were gathered using online and paper-based

The personal administrative officer (personlig handläggare) is a new professional role that recently has been introduced by the Swedish National Social Insurance Agency (Försäkringskassan). This report concerns how this professional role is interpreted – covering both the official definition of the National Social Insurance Agency and the individual interpretations of the administrative officers w

Popular Abstract in Swedish Läkemedel blir allt viktigare behandlings-instrument och kunskapen ökar om läke-medels verkningsmekanismer. Även om denna kunskap kombineras med resultat från kliniska läkemedelsprövningar är detta dock inte tillräckligt för att värdera kliniska fördelar och risker med en rutinmässig läkemedels-behandling, särskilt inte om behandlingen är långvarig. För detta ändamål beThe efficacy and safety of antihyperglycaemic drugs have been evaluated in one American and one British randomized clinical trial, which have given contradictory results. The positive results of the latter may be more convincing as it included a greater number of patients and as its duration was longer. However, its conclusions may not be applicable to type 2 diabetes patients in general, as the s

Perfluoroalkyl acids (PFAAs) are a large group of chemicals which are highly persistent in both nature and humans. The use of the most prominent ones, perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), was reduced in the early 21st century, and since then levels in human matrices have decreased. However, these two compounds have been exchanged by other PFAAs, for which time trends

This experimental study examines the influence of moisture variations on the load-bearing capacity of steel-timber dowel joints. The glulam specimens used to manufacture the joints were first exposed to controlled climate changes. After being stored in the climate chambers, holes were drilled and dowels were inserted. Then, the joints were loaded to failure. The main aim of this study was to inves

This experimental study examines the influence of moisture variations on the load-bearing capacity of steeltimber dowel joints. The glulam specimens used to manufacture the joints were first exposed to controlled climate changes. After being stored in the climate chambers, holes were drilled and dowels were inserted. Then, the joints were loaded to failure. The main aim of this study was to inv

OBJECTIVE: Cholecystectomy is the standard treatment for acute cholecystitis, but in high-risk patients with serious comorbidity and in patients of advanced age there is substantial morbidity and mortality associated with the intervention. In these selected patients, percutaneous cholecystostomy (PCS) is an alternative mode of management. The aim of the present study was to evaluate the outcome of

Popular Abstract in Swedish Patienten med underbensamputation på grund av kärlsjukdom Långt före Kristi födelse var amputation av benet en känd operation. Anledningen till amputationen kunde vara kärlsjukdom, olycksfall, tumör eller medfödda missbildningar. I västvärlden idag utförs 90 % av amputationerna på grund av kärlsjukdom. Dessa patienter är äldre och sjukare än övriga benamputerade och meThe patient with unilateral trans-tribal amputation for vascular disease. Functional assessments, prognostic factors and cost of prostheses. The aims of the study were to focus on the functional ability of the dysvascular patient with unilateral trans-tibial amputation and the early rehabilitation period, defined here as the period between the amputation and the prosthetic fitting. Results revea

Fourteen genera belong to a monophyletic core of cetrarioid lichens, Ahtiana, Allocetraria, Arctocetraria, Cetraria, Cetrariella, Cetreliopsis, Flavocetraria, Kaernefeltia, Masonhalea, Nephromopsis, Tuckermanella, Tuckermannopsis, Usnocetraria and Vulpicida. A total of 71 samples representing 65 species (of 90 worldwide) and all type species of the genera are included in phylogentic analyses based

This thesis investigates the female novel of development as a specific genre, focusing on Swedish 20th century literature. In the first three chapters, three trilogies are examined, namely Agnes von Krusenstjerna's series about a titled girl (I922-26), Irja Browallius' novels about a foster girl (1957-61), and Ingrid Sjöstrand's series of collective novels about a group of girls from a girls' scho

Abstract Objectives. To investigate whether coronary microemboli have long-term effects on left ventricular (LV) function in an experimental model. Furthermore, to determine if first-pass perfusion and late gadolinium enhancement (LGE) patterns differs between small- and large-sized microemboli. Design. Six pigs underwent left anterior descending (LAD)-coronary microembolization with small-sized (

Popular Abstract in Swedish Överdosens antropologi behandlar narkotikaöverdosens sociala konsekvenser. Eva-Malin Antoniusson har studerat hur olika aktörer i vård- och institutionsmiljöer förhåller sig till överdoser. Forskningen bygger på fältundersökningar i Sverige, USA och Nederländerna. I avhandlingen återges intervjuer med narkomaner som överlevt överdoser eller varit med när andra överdoserThe central theme of this thesis is the nature of heavy drug overdose and its social consequences. The aim of the study is to provide a nuanced ethnographic interpretation on the phenomenon concerning drug overdose, especially among drug users using injections as the principle means of administering the drugs. The field study was localized to institutional milieus, primarily drug addiction treatme

Popular Abstract in Swedish Laserbaserd Förbränningsdiagnostik - Elastisk Spridning och Pikosekundlaserinducerad fluorescens Elastisk spridning och Lorenz-Mie (LM) teorin används för att karakterisera droppar av organiskt bränlse med en diameter kring 1 mikrometer. Beräkningar baserade på LM-teorin visar att det spridda ljuset i sido- och bakåtrikningen kan användas för omisskänslig detektion av Elastic scattering and the Lorenz-Mie (LM) theory in particular is used for the characterization of sub-micron- and micron-sized droplets of organic fuels in sprays and aerosols. Calculations on the Lorenz- Mie theory show that backward-sideward scattered visible radiation can be used for unambiguous detection of ensembles of homogeneous droplets of organic substances with diameters around 1 micro