4MOST is a new high-multiplex, wide-field spectroscopic survey facility under construction for ESO's 4m-VISTA telescope at Paranal, Chile. Its key specifications are: a large field of view of 4.4 square degrees, a high multiplex fibre positioner based on the tilting spine principle that positions 2436 science fibres in the focal surface of which 1624 fibres go to two low-resolution optical spectro

BACKGROUND: Knee osteoarthritis (OA) is a major public health issue causing chronic pain, impaired physical function, and reduced quality of life. As there is no cure, self-management of symptoms via exercise is recommended by all current international clinical guidelines. This review updates one published in 2015.OBJECTIVES: We aimed to assess the effects of land-based exercise for people with kn

Background: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a heterogenous autoimmune disease. While traditionally stratified into two conditions, granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), the subclassification of ANCA-associated vasculitis is subject to continued debate. Here we aim to identify phenotypically distinct subgroups and develop a da

Simultaneous digital breast tomosynthesis and mechanical imaging (DBTMI), a novel screening approach, combines anatomic DBT with functional analysis of the stress distribution on the compressed breast by mechanical imaging (MI). Preliminary studies suggest potential to reduce false positive findings. DBTMI requires to align DBT and MI images. In this study, we have analyzed robustness to alignment

In this study, we assess the impact of an image restoration pipeline, designed for digital mammography, on the detectability of microcalcifications of different sizes across varied radiation exposures. The restoration pipeline first removes the noise of the image considering a Poisson-Gaussian noise model that incorporates quantum and electronic noise. Then, it appropriately merges the noisy and d

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https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/privat/akademikerforbunden/fortroendevald/ - 2025-08-05

https://www.sol.lu.se/media/utbildning/dokument/kurser/FIMN01/20152/FIMN01.pdf - 2025-08-05

The emission spectra of lithium orthosilicates (Li4SiO4) ceramics have been measured in the range of 1.8-5.8 eV under irradiation by 6-30 eV photons or 1-30 keV electrons at 6-300 K. The tunnel recombination phosphorescence, as well as luminescence, stimulated by 1.5-2.5 eV photons has been detected in the sample preliminarily irradiated at 6 or 80 K. The main peaks of thermally stimulated lumines

Several transporter systems in the liver and intestine are known to change their expression and function during cholestatic disease states. The objective of the-present in vivo study-was to investigate the effect of biliary depletion, as a method to mimic cholestasis, on the bioavailability and disposition of digoxin in biliary and pancreatic duct cannulated pigs. The study was divided in two part

Whilst innate B1-B cells are atheroprotective, adaptive B2-B cells are considered pro-atherogenic. Different subsets of B regulatory cells (B-reg) have been described. In experimental arthritis and lupus-like disease, B-reg are contained within the CD21(hi)CD23(hi)CD24(hi) B cell pool The existence and role of B-reg in vascular disease is not known. We sought to investigate the existence, identity

How hard are geometric vision problems with outliers? We show that for most fitting problems, a solution that minimizes the num- ber of outliers can be found with an algorithm that has polynomial time- complexity in the number of points (independent of the rate of outliers). Further, and perhaps more interestingly, other cost functions such as the truncated L2 -norm can also be handled within the

When decision on repair has been taken the available repair systems/methods must be evaluated with regard to the immediate requirements. For each type and cause of damage, there are normally only a few possible repair systems. These repair systems should be evaluated with regard to following 5 basic properties, or characteristics: 1) service life/durability, 2) structural stability/safety, 3) exec

Objectives To develop a score for assessment of patients' symptoms in primary Sjogren's syndrome (SS): the EULAR SS Patient Reported Index (ESSPRI). Methods Dryness, pain, somatic and mental fatigue were identified as the main symptoms of patients with primary SS, in studies developing the Profile of Fatigue and Discomfort (PROFAD) and Sicca Symptoms Inventory (SSI). It was suspected that a single

Background: Cystatin C may add explanatory power for associations with mortality in combination with other filtration markers, possibly indicating pathways other than glomerular filtration rate (GFR). However, this has not been firmly established since interpretation of associations independent of measured GFR (mGFR) is limited by potential multicollinearity between markers of GFR. The primary aim

Calcium sulfate/hydroxyapatite (CaS/HA) biomaterials have been investigated for use in several orthopedic applications. However, the mechanical interactions between the composite of CaS/HA and bone at the microscale are still unknown. The aim of this study was to determine if and how augmentation with CaS/HA alters the fracture behavior of bone. Eleven cylinders of trabecular bone were drilled fro

Aquaporins play a crucial role in water homeostasis in the human body, and recently the physiological importance of aquaporins as glycerol channels have been demonstrated. The aquaglyceroporins (AQP3, AQP7, AQP9 and AQP10) represent key glycerol channels, enabling glycerol flux across the membranes of cells. Adipocytes are the major source of glycerol and during lipolysis, glycerol is released to

The Open XAL accelerator physics software platform is being developed through an international collaboration among several facilities since 2010. The goal of the collaboration is to establish Open XAL as a multi-purpose software platform supporting a broad range of tool and application development in accelerator physics (Open XAL also ships with a suite of general purpose accelerator applications)

There are hundreds of thousands of moth species with crucial ecological roles that are often obscured by their nocturnal lifestyles. The pigmentation and appearance of moths are dominated by cryptic diffuse shades of brown. In this study, 82 specimens representing 26 moth species were analysed using infrared polarimetric hyperspectral imaging in the range of 0.95–2.5 µm. Contrary to previous studi

Risk-based inspection (RBI) planning is concerned with the optimal allocation of deterioration control which is based on the pre-posterior analysis using the Bayesian decision theory and the expected utility theory. It has been widely used to make inspection and repair strategy in the field of civil engineering and infrastructure systems. Nowadays, with the developments of sensing and inspection t

Importance: There are limitations in current diagnostic testing approaches for Alzheimer disease (AD). Objective: To examine plasma tau phosphorylated at threonine 217 (P-tau217) as a diagnostic biomarker for AD. Design, Setting, and Participants: Three cross-sectional cohorts: an Arizona-based neuropathology cohort (cohort 1), including 34 participants with AD and 47 without AD (dates of enrollme