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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193234 sökträffar

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An apparatus for sorption measurements has been built and tested. Control of temperature, relative humidity and air velocity over long periods of time have been the main objectives. The article contains a description of the instrument and its performance characteristics.

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The purpose of this study was to determine the capacity of cells transduced with human beta-defensins (HBDs) to express antimicrobial peptides, since sufficient expression level is required for effective antimicrobial activity. Retroviral vector pBabeNeo and lentiviral vector SIN18cPPTRhMLV (SIN18) carrying HBDs were utilized to transduce non-HBD-expressing cells such as fibroblasts or HBD-produci

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The solubility of tri-n-octylamine (TOA) in water and phosphoric acid is reported. Equilibration is achieved by circulating the solutioin through PVC pieces saturated with the absorbed amine in a glass tube. The dissolved TOA is determined by capillary gas chromatography which can detect amine concentrations down to 10 μg l−1. The solubility of TOA in water is 0.039 mg l−1 and in 5.5 M phosphoric

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Motivated by a desire to understand and optimize combustion in spark-ignition (SI) engines, laser techniques have been developed for measurement of fuel and residual gas, respectively, in the precombustion mixture of an operating SI engine. The primary objective was to obtain two-dimensional, quantitative data in the vicinity of the spark gap at the time of ignition. A laser-induced fluorescence

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We investigate shot noise of photon-excited electron-hole pairs in open multiterminal, multichannel chaotic dots. Coulomb interactions in the dot are treated self-consistently giving a gauge-invariant expression for the finite frequency correlations. The Coulomb interactions decrease the noise; the strong interaction limit coincides with the noninteracting adiabatic limit. Inelastic scattering and

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The breeding biology of a southern population of the little-known Savi’s Warbler Locustella luscinioides is described and compared with other parts of its distribution and other species. Males arrived at the Salreu marshlands, Portugal, in the second week of March whereas females arrived 6–10 days later. Early-arriving males bred earlier and had greater mating and breeding success. Female breeding

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Pollen competitive ability depends on the innate capacity of a pollen donor to produce pollen that reaches the ovules fast, but could also be a consequence of the ability to interfere with pollen from other donors. In a greenhouse study on Viola tricolor, we examined the relative importance of both of these effects by performing crosses where we varied the pollen load composition of two donors. We

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The force-velocity relation of the rat portal vein has been studied during regular spontaneous contractions induced by elevated levels of [K-+]O AND [Ca-2+]o. No satisfactory description of the force-velocity relation was obtained by measuring shortening velocity in afterloaded isotonic contractions. Therefore the method of isotonic quick release was used, as this permits mechanical studies at spe

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SO2 dry deposition was studied over short vegetation, in Portugal, by means of the concentration gradient method. The experimental study involved one first phase of long-term measurements carried out in a grassland and, subsequently, a second period of several 1997 intensive field campaigns performed in three places representing different climate and surface conditions. Temporal and spatial patter

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The Rio Artiguas basin in central Nicaragua shows a distinctive case of environmental deterioration due to anthropogenic activities. Heavy metals used in gold mining and other wastes are continuously released into the rivers, representing a threat to the water quality. This article aims to evaluate the groundwater intrinsic vulnerability in the Rio Artiguas basin and to provide information for sus

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The gamma decay of the 12(+) yrast trap in Fe-52 has been measured for the first time. The two E4 gamma-branches to the 8(+) states are hindered with respect to other B(E4) reduced transition probabilities measured in the f(7/2) shell. The interpretation of the data is given in the full pf shell model framework, comparing the results obtained with different residual interactions. It is shown that

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Endothelin is a vasoactive peptide that exerts its effect through two receptors; the endothelin type A (ETA) and type B (ETB) receptor. The contractile ETA receptor is localized on smooth muscle cells in the vascular wall, while the ETB receptors are mainly situated on endothelial cells, mediating vasodilatation. The endothelin system is involved in several pathophysiological conditions, such as a

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Inclusive jet cross sections are measured in photoproduction at HERA using the H1 detector. The data sample of e(+)p --> e(+) + jet + X events in the kinematic range of photon virtualities Q(2) less than or equal to 1GeV(2) and photon-proton centre-of-mass energies 95 less than or equal to W-gammap less than or equal to 285GeV represents an integrated luminosity of 24.1pb(-1). Jets are defined usi

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Starting from a corpus of German spontaneous speech, the phonetic realisations of the two KIM categories medial and late peak were investigated in prenuclear position. The results show that, for both categories, the onset of the rising F0 movement (L) is comparably aligned around the accented-syllable onset, whereas the F0 maximum (H) is independently aligned and predominantly located before the a