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Serotonin (5-HT) is a biogenic monoamine that functions both as a neurotransmitter and a circulating hormone. Recently, the metabolic effects of 5-HT have gained interest and peripheral 5-HT has been proposed to influence lipid metabolism in various ways. Here, we investigated the metabolic effects of 5-HT in isolated, primary rat adipose cells. Incubation with 5-HT suppressed β-adrenergically sti

User driven innovation (UDI) is a popular term in policy and corporate circles. However, it is not clear exactly what UDI means and how such practices are used across the spectrum of companies and over the innovation life cycle. The present study compares 58 UDI showcases in Finnish companies in order to analyse the diversity of UDI practices and their evolution over time. We identify five main mo

Altricial birds are unable to maintain body temperature when exposed to low ambient temperatures during the first days after hatching. Thermoregulatory capacity begins to form as postnatal development progresses, and eventually nestlings become homeothermic. Several factors may influence this development at both the level of the individual and the level of the whole brood, but to our knowledge no

Several recent models of choice build on the idea that decision makers are more likely to choose an option if its attributes stand out compared to the attributes of the available alternatives. One example is the model of focusing by Köszegi and Szeidl (2013) where decision makers focus disproportionally on the attributes in which the available options differ more, implying that some attributes wil

A recently developed method for quantitative assessment of regional lung ventilation was employed for the study of posture-dependent ventilation differences in rats. The measurement employed hyperpolarized (3)He MRI to detect the build-up of the signal intensity after increasing numbers of (3)He breaths, which allowed for computation of a regional ventilation parameter. A group of six anesthetized

Following the recent detection of an auroral signal on Uranus (Lamy et al. [2012]. Geophys. Res. Lett. 39, 7105) during HST/STIS observation performed in November 2011, we analyzed the associated HST/STIS FUV spectral images obtained in 2011 and 2012. Our purpose was to extract any possible H2 emission produced in the upper atmosphere of the planet. To interpret these data, we adapted a version of

Locally induced, magnetic order on the surface of a topological insulator nanowire could enable room-temperature topological quantum devices. Here we report on the realization of selective magnetic control over topological surface states on a single facet of a rectangular Bi2Te3 nanowire via a magnetic insulating Fe3O4 substrate. Low-temperature magnetotransport studies provide evidence for local

Collective identities of the Self vs. the Other are not only conveyed in and between cultures through verbal discourse, but also through pictures. Cultural encounters are often comprehended by storytelling, the verbal expression of which has been abundantly studied. Pictorial manifestations of narration, however, have received comparatively less attention. Mostly

A commonly held view is that strategic organization theories progress as a result of a Popperian process of bold conjectures and systematic refutations. However, our field also witnesses vibrant debates or disputes about the specific assumptions that our theories rely on, and although these debates are often decoupled from the results of empirical testing, changes in assumptions seem closely inter

Type 2 diabetes (T2D) results from a co-occurrence of genes and environmental factors. There are more than 120 genetic loci suggested to be associated with T2D, or with glucose and insulin levels in European and multi-ethnic populations. Risk of T2D is higher in the offspring if the mother rather than the father has T2D. Genetically, this can be associated with a unique parent-of-origin (PoO) tran

INTRODUCTION: Non-native linguistic tone learning ability has been found to be influenced by the anatomy of primary auditory regions in the left hemisphere (Wong et al., 2008). In native speakers, however, where phonemic categories are firmly established, variations in the macrostructure of more secondary auditory processing areas might be expected to affect performance. The present study investig

Recent research on the process of biological phosphorus removal in lab-scale treatment systems has indicated that: (i) the development of an actively poly?-accumulating bacterial community after the introduction of an anaerobic period may take at least 4 months; (ii) up to 80% of all aerobic bacteria isolated from these communities are able to accumulate polyP; (iii) polyP synthesized by the bacte