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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 114853 sökträffar

Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy : A Meta-Analysis

Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organize

High-throughput spectroscopy of semiconductor nanowires in the presence of inhomogeneity

Controllable doping in semiconductor nanowires is essential for development of optoelectronic devices. Despite great progress, a fundamental challenge remains in controlling the uniformity of doping, particularly in the presence of relatively high levels of geometrical inhomogeneity in bottom-up growth. A relatively high doping level of 1E18 cm-3 corresponds to just ~1000 activated dopants in a 2µ

Diffusion MRI with pulsed and free gradient waveforms : effects of restricted diffusion and exchange

Monitoring time-dependence with diffusion MRI yields observables sensitive to compartment sizes (restricted diffusion) and membrane permeability (water exchange). However, restricted diffusion and exchange have opposite effects on the diffusion-weighted signal, which can lead to errors in parameter estimates. In this work, we propose a signal representation that incorporates the effects of both re

Claims in the clinic: tensions in healthcare communication about perceived side effects of the copper IUD

A large share of health-related information is today sought and communicated via the internet, including in social media. Questions have been raised about how this may affect health perceptions and behaviors, not least by enabling the communication of claims that contradict information from established medical authorities. As an example, knowledge claims about systemic side effects of the contrace

From electronic structure to combustion model application for acrolein chemistry Part Ⅱ : Acrolein + HȮ2 reactions and the development of acrolein sub-mechanism

Acrolein, as one of the most hazardous aldehydes, can be formed among the carbonyls from the combustion of bio-fuels or mixtures of bio- and conventional fuels. Moreover, acrolein is also an important combustion intermediate in the oxidations of higher unsaturated hydrocarbons. A deep understanding of acrolein combustion chemistry will be useful for the kinetic modeling of higher hydrocarbons and

Road salt damage to historical milestones indicates adaptation of winter roads to future climate change may damage arctic cultural heritage

There is no doubt that anthropogenic global warming is accelerating damage to cultural heritage. Adaptation measures are required to reduce the loss of sites, monuments and remains. However, little research has been directed towards understanding potential impacts of climate adaptation measures in other governmental sectors on cultural heritage. We provide a case study demonstrating that winter ro

ErbB2 status and the benefit from two or five years of adjuvant tamoxifen in postmenopausal early stage breast cancer

AIM: We aimed to study the importance of erbB2 status in early stage postmenopausal breast cancer for patients who participated in a trial of five vs. two years of adjuvant tamoxifen.PATIENTS AND METHODS: We analysed the erbB2 status of the tumours from 577 patients participating in the trial, either by a DNA amplification assay (n = 181) or by measurement of the protein level with flow cytometry

Pushing the MAX IV 3 GeV storage ring brightness and coherence towards the limit of its magnetic lattice

The MAX IV 3 GeV storage ring is presently being commissioned and crucial parameters such as machine functions, emittance, and stored current have either already been reached or are approaching their design specifications [1, 2]. Once the baseline performance has been achieved, a campaign will be launched to further improve the brightness and coherence of this storage ring for typical x-ray users.

Peritoneal metastases found in routinely resected specimens after cytoreductive surgery and heated intraperitoneal chemotherapy

Introduction: Peritoneal metastases (PM) originating from colorectal cancer (CRC) and pseudomyxoma peritonei (PMP) can be treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Certain sites in the peritoneal cavity are prone to contain PM and are, therefore, routinely resected. The aim of this study is to investigate the frequency of disease in CRS specime

Physician's conceptions of the decision-making process when managing febrile infants ≤ 60 days old : a phenomenographic qualitative study

BACKGROUND: The management of febrile infants aged ≤ 60 days and adherence to guidelines vary greatly. Our objective was to describe the process of decision-making when managing febrile infants aged ≤ 60 days and to describe the factors that influenced this decision.METHODS: We conducted 6 focus group discussions with 19 clinically active physicians in the pediatric emergency departments of 2 univ

Portal vein embolization with N-butyl-cyanoacrylate improves liver hypertrophy compared to microparticles – A Swedish multicenter cohort study

Background: An adequate future liver remnant (FLR) is fundamental for major liver resections. To achieve sufficient FLR, portal vein embolization (PVE) may be used. The most effective material for PVE has yet to be determined. The aim of this study was to investigate the differences in FLR growth between n-butyl-cyanoacrylate glue (NBCA) and microparticles. Material/methodsa: retrospective study w

Media Tactics in the Long Twentieth Century

Integrating media studies with history, Media Tactics in the Long Twentieth Century explores the dynamic relationship between tactics and strategies in recent history. Drawing on examples from a range of different countries and world regions, and looking at the infrastructures, entanglements, and institutions involved, the volume makes a strong case for media tactics as a new field of scholarly in

An international study of diversity in occupational therapy research– A bibliographic review of English research literature

Background: The cornerstone of a strong profession is the research that supports its knowledge base and practice. However, little is known about the range of international occupational therapy research. Objective: To explore the range and diversity of the international occupational therapy research from published peer reviewed literature in English during the year 2018. Methodology: Limited to 201

Accessible and reliable neurometric testing in humans using a smartphone platform

Tests of human brain circuit function typically require fixed equipment in lab environments. We have developed a smartphone-based platform for neurometric testing. This platform, which uses AI models like computer vision, is optimized for at-home use and produces reproducible, robust results on a battery of tests, including eyeblink conditioning, prepulse inhibition of acoustic startle response, a

Communication Differences between Oncologists and Palliative Care Clinicians : A Qualitative Analysis of Early, Integrated Palliative Care in Patients with Advanced Cancer

BACKGROUND: Growing evidence demonstrates the benefits of early, integrated palliative care (PC) for patients with advanced cancer and their caregivers. Yet, data are lacking on the communication patterns within this model of care.OBJECTIVE: The goals of this study were to describe the content of patient-clinician discussions among patients receiving PC and to compare differences in discussion con

Enzymatic transformations in supersaturated substrate solutions : II. Synthesis of disaccharides via transglycosylation

Enzymatic transglycosylation in supersaturated solutions of substrates was investigated using crude glycosidase preparations from barley, snail, and coffee beans. It was shown that the use of supersaturated glycoside solutions as media for transglycosylation reactions offers considerable advantages over conventional aqueous systems. These advantages include higher yields, more efficient use of the

Parent-teacher trust as a relational pathway to the child: Teachers’ perceptions about child-teacher-parent relationship-building during the child’s transition to preschool

Beyond interactions with parents, young children’s development is influenced by attachment-related interactions with close caregivers in different contexts, such as with teachers at professional childcare centres (“preschool”). The child’s transition from the home environment to being cared for at preschool for the very first time is essential in this respect, providing a natural “window of opport

Förändrade stödnivåer i jordbrukspolitiken – hur påverkas produktion, konkurrenskraft och miljö?

Den gemensamma jordbrukspolitiken (CAP) reformeras regelbundet och arbetet pågår nu inför nästa programperiod som börjar 2028. En betydande del av jordbruksstöden utgörs av gårdsstöd, nötkreatursstöd, kompensationsstöd, omfördelningsstöd och ersättning till naturbetesmarker. Vi analyserar hur förändringar av nivåerna på dessa stöd skulle påverka jordbrukets produktion, konkurrenskraft och miljöpåv