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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 114853 sökträffar

Enzymatic transformations in supersaturated substrate solutions : II. Synthesis of disaccharides via transglycosylation

Enzymatic transglycosylation in supersaturated solutions of substrates was investigated using crude glycosidase preparations from barley, snail, and coffee beans. It was shown that the use of supersaturated glycoside solutions as media for transglycosylation reactions offers considerable advantages over conventional aqueous systems. These advantages include higher yields, more efficient use of the

Parent-teacher trust as a relational pathway to the child: Teachers’ perceptions about child-teacher-parent relationship-building during the child’s transition to preschool

Beyond interactions with parents, young children’s development is influenced by attachment-related interactions with close caregivers in different contexts, such as with teachers at professional childcare centres (“preschool”). The child’s transition from the home environment to being cared for at preschool for the very first time is essential in this respect, providing a natural “window of opport

Förändrade stödnivåer i jordbrukspolitiken – hur påverkas produktion, konkurrenskraft och miljö?

Den gemensamma jordbrukspolitiken (CAP) reformeras regelbundet och arbetet pågår nu inför nästa programperiod som börjar 2028. En betydande del av jordbruksstöden utgörs av gårdsstöd, nötkreatursstöd, kompensationsstöd, omfördelningsstöd och ersättning till naturbetesmarker. Vi analyserar hur förändringar av nivåerna på dessa stöd skulle påverka jordbrukets produktion, konkurrenskraft och miljöpåv

Fathers’ Experiences Six Months After their Preterm Infant's Discharge from the NICU

Although fathers experience emotional stress both during the care period and after discharge, there is limited research focusing exclusively on fathers’ experiences after their time in a neonatal intensive care unit. Their experiences are important for tailoring support to fathers based on their individual needs. This paper is part of a longitudinal study in which parents were followed by means of

Local interactions and protein folding : A three-dimensional off-lattice approach

The thermodynamic behavior of a three-dimensional off-lattice model for protein folding is probed. The model has only two types of residues, hydrophobia and hydrophilic. In absence of local interactions, native structure formation does not occur for the temperatures considered. By including sequence independent local interactions, which qualitatively reproduce local properties of functional protei

Evaluating a GUI Development Tool for Internet of Things and Android

In the emerging field of Internet of Things (IoT), where computerized devices are combined in creative new ways, there is a need to create Graphical User Interfaces (GUIs) for the systems being built, e.g. in the form of Android “apps”. This is generally a complicated, time consuming task. We report from a controlled experiment that evaluates a new approach for building GUIs that aims to make it e

In search of building types : On visitor centers, thresholds and the territorialisation of entrances

The aim of this paper is to contribute to an actantial approach to building type studies through a study of the visitor centre and its role in contemporary spatial production. The article takes its empirical departure in the (from a Swedish perspective) intense urbanization of the Scania region, in the southern part of Sweden. Looking at building types in terms of actants implies that different se

Sunscreen use and malignant melanoma

In a new population-based, matched, case-control study from southern Sweden of 571 patients with a first diagnosis of cutaneous malignant melanoma, between 1995 and 1997, and 913 healthy controls aged 16 to 80 years, the association between sunscreen use and malignant melanoma was evaluated. The median sun protection factor (SPF) used by both cases and controls was 6, range 2 to 25. Sunscreen user

Use of antihistamine drugs in early pregnancy and delivery outcome.

OBJECTIVE: To study the impact of antihistamine use in early pregnancy on delivery outcome. METHODS: Using prospectively collected information on drug use in early pregnancy, delivery outcome was studied among 17 266 women with 17 776 deliveries and 18 197 infants. The analysis was performed according to the main reason for antihistamine use: nausea and vomiting in pregnancy and allergy. RESULTS:

Interacting effects of farming practice and landscape context on bumble bees

Organic farming has been suggested to counteract declines in farmland biodiversity, but comparisons to conventional farming have produced variable outcomes. To examine whether this is due to the landscape context farms are situated in and traits of the studied organisms, we surveyed bumble bees in cereal field borders and margins at 12 pairs of matched organic and conventional farms, with half the

Quasi diabatic CASSCF state functions

A new method to determine quasi diabatic (QD) CASSCF states is presented. The adiabatic states are subjected to a unitary transformation resulting from diagonalization of a state-selection operator. The latter is constructed from the overlap of the adiabatic states with a suitable set of reference states. The multi-state (MS) CASPT2 method is used to account for the dynamical correlation effects i

Towards accurate in vivo spectroscopy of the human prostate

The recent interest in photodynamic therapy of human prostate cancer is accompanied by a need for techniques for in vivo monitoring of optical and physiological characteristics. We propose time-of-flight (TOF) spectroscopy in combination with Monte Carlo evaluation as a reliable optical technique for quantitative assessment of absorption, scattering, hemoglobin content and tissue oxygenation in th

Role of the ProteinTyrosine Phosphatase SHP-I in Interleukin-6 Regulation of Prostate Cancer Cells

BACKGROUND. Interleukin-6 (IL-6) is a multifunctional cytokine that has been implicated in the modulation of growth and progression of prostate cancer. Decreased expression of the tyrosine phosphatase SHP-1, involved in regulation of cytokine and tyrosine kinase receptor signaling, has been shown to be associated with less favorable outcome among prostate cancer patients. METHODS. Parental LNCaP c

Host specificity and repeatability of haemosporidian infection parameters—potential consequences when testing host species-level hypotheses

In their seminal hypothesis, Hamilton and Zuk proposed parasites to drive host sexual selection and predicted infections to correlate with ornamentation. Since then, a plethora of studies has explored how parasite occurrence relates to host traits, though the underlying assumption that parasite infection parameters are host-specific traits has rarely been evaluated. We used a global database (MalA

Second-generation migrants in Italy: Navigating media representations between formal inclusion and exclusion

The focus of this thesis is to examine how the civic identity of the second-generation migrants in Italy is constructed through media representations of migration, citizenship, and national belonging. Previous studies focused on migrants’ integration, which was based on their socio-economic situation, mobility, and assimilation process. I argue that these approaches are insufficient to explain how

Enzyme-based Approaches to Caries Prevention : Characterization and Disruption of Cariogenic Biofilms in In Vitro Models

Introduction: Enzyme-based approaches have shown promise in a more targeted alternative for treating oral diseases such as caries. Given the high global prevalence of caries, and ecological complexity of the oral microbiome, investigating selective treatment strategies is of significant interest. Background: The oral microbiome is a dynamic, polymicrobial community, dependent on ecological balance