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Automatic local memory architecture generation for data reuse in custom data paths

Traditional high level synthesis is able to yield high computational resource utilisation and short critical paths. The shortcomings of the generated designs usually lies in the memory architecture. To achieve good performance on a FPGA, the data must reside in the fast on-chip memories, but these are commonly too small for the data being processed. Traditional high level synthesis cannot cope wit

Plasma membrane/cytoskeleton interactions in plants

The way in which the cortical cytoskeleton associates to the plasma membrane (PM) must be elucidated to understand the structural dynamics of many processes in the plant cell. In the present study, isolated cauliflower (Brassica oleracea L.) PM vesicles were used to characterize membrane/cytoskeleton interactions. Both actin and tubulin were shown to copurify with PM vesicles and this copurificati

On visual impairment in Swedish children

Popular Abstract in Swedish I världen beräknas det finnas cirka 38 miljoner blinda människor enligt Värdshälsoorganisationen (WHO). Av dessa är 1,5 miljon barn under 16 år. Blindhet definieras av WHO som bästa korrigerade synskärpa under 0,05 (man klarar således inte att läsa översta raden på en vanlig synprövningstavla på halva normalavståndet), detta med bästa glasögonkorrektion och med båda ögoKnowledge of the epidemiology of visual impairment in children forms one of the cornerstones in paediatric ophthalmology. To gain an overview of the situation in Sweden an epidemiological study was performed. Totally 2373 visually impaired children were found, giving an age-specific prevalence of 10,9/10 000. Childhood blindness (i.e. vision <0,05) was seen in 25%. Male/female ratio was 1,20. Addi

On the estimation of ligand binding affinities

Popular Abstract in Swedish De allra flesta människor har vid något tillfälle tagit ett läkemedel. Till exempel vaccineras nu för tiden alla svenska barn mot bland annat stelkramp. Vad nog de allra flesta däremot inte har gjort är att fundera på vad ett läkemedel är. Kanske sträcker man sig till att ha kollat upp ett läkemedel i FASS, och kanske får man då syn på en figur som består av streck och A method to accurately estimate the binding affinity of a small molecule to a receptor would be indispensable in numerous fields. For instance, most drugs exert their action by binding to a macromolecule target. Thus, a lot of time and resources could be saved in drug design by predicting affinities by computer programs. In a series of 15 papers, we have tested, compared, and improved the most p

Remote analysis of gas mixtures using an optical parametric oscillator based lidar system

A scheme for lidar measurements of multicomponent gas mixtures in the mid-IR region using a newly developed fast-switching, frequency-agile optical parametric oscillator (OPO) system combined with multivariate statistical methods has been implemented and tested. The scheme adopted was able to predict the composition of the remote hydrocarbon gas mixture within the uncertainty of the pre-determined