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Primary sensory neurons serve a dual role as afferent neurons, conveying sensory information from the periphery to the central nervous system, and as efferent effectors mediating, e.g., neurogenic inflammation. Neuropeptides are crucial for both these mechanisms in primary sensory neurons. In afferent functions, they act as messengers and modulators in addition to a principal transmitter; by relea

Reliable verification of damage claims is fundamental to create public trust in the legitimacy of compensation programs, and avoid fraud and moral hazards. However, after decades of using this tool, transparency in verification processes and availability of quantitative information on the accuracy and misidentification rates are unresolved issues. Accurate rules overcome several challenges facing

Vassilevska and Williams (STOC'09) showed how to count simple paths on k vertices and matchings on k/2 edges in ann-vertex graph in time nk/2+O(1). In the same year, two different algorithms with the same runtime were given by Koutis and Williams (ICALP'09), and Bjorklund et al. (ESA'09), via nst/2+O(1)-time algorithms for counting t-tuples of pairwise disjoint sets drawn from a given family of s-

The methods developed for secondary analysis of nested case-control data have been illustrated only in simplified settings in a common cohort and have not found their way into biostatistical practice. This paper demonstrates the feasibility of reusing prior nested case-control data in a realistic setting where a new outcome is available in an overlapping cohort where no new controls were gathered

Mass extinction events are recognized by increases in extinction rate and magnitude and, often, by changes in the selectivity of extinction. When considering the selective fingerprint of a particular event, not all taxon extinctions are equally informative: some would be expected even under a ‘background’ selectivity regime, whereas others would not and thus require special explanation. When evalu

OBJECTIVES: The aim of the present study was to prospectively explore the detailed longitudinal development of platelet increments in patients with chemotherapy-induced bone marrow aplasia during the first 24 hours after platelet transfusion.METHODS: Patients admitted to the Haematology department during 7 months and fulfilled inclusion criteria were divided into 4 groups: Group 1, patients with a

Best use of scientific knowledge is required to maintain the fundamental role of seafood in human nutrition. While it is acknowledged that genomic-based methods allow the collection of powerful data, their value to inform fisheries management, aquaculture, and biosecurity applications remains underestimated. We review genomic applications of relevance to the sustainable management of seafood resou

In Sweden there has been a move towards more cost reflective price models for district heating in order to reduce economic risks that comes with variable heat demand and high shares of fixed assets. The keywords in the new price models are higher shares of fixed cost, seasonal energy prices and charging for capacity. Also components that are meant to serve as incentives to affect behaviour are int

Today, digitalization is the single most significant change factor for the construction sector as well as for society in general, which will bring new opportunities for intelligent and sustainable cities, efficient management of available resources and a general reduction of carbon emissions. Digitalization will enable continuous and integrated information exchange between all actors of the constr

This case-note analyses the international award recently published in the case of Philip Morris Asia Limited v. The Commonwealth of Australia. Engaging particularly with the application of the Arbitration Tribunal of the abuse of rights doctrine, the note addresses, in the light of this award, a series of questions that continue to perplex international investment lawyers. How should the concept o

Ambitions and ClarificationsThe book takes its point of departure in the "intimate visions of society" that are significant of contemporary social life. This concept refers to the tendency to apprehend good social relations as personal, close and warm, while bad relations correspondingly are perceived as impersonal, cold, distant and alienated. Exemplary categories, such as closeness, warmth, commAmbitions and ClarificationsThe book takes its point of departure in the "intimate visions of society" that are significant of contemporary social life. This concept refers to the tendency to apprehend good social relations as personal, close and warm, while bad relations correspondingly are perceived as impersonal, cold, distant and alienated. Exemplary categories, such as closeness, warmth, comm

Flow field design of fuel cells has a significant impact on the distribution of the reactants over the active surface area. In this work, the cell performance and transport characteristics of high temperature proton exchange membrane fuel cells with metal foams as flow distributor were numerically investigated by a three-dimensional and non-isothermal model. Compared to the fuel cell with conventi

Laminar methane/air premixed flames at different pressures in a newly developed high-pressure Bunsen flame rig are studied using detailed numerical simulations and laser diagnostics. In the numerical simulations, one-dimensional and two-dimensional axisymmetric configurations were considered employing detailed transport properties and chemical kinetic mechanisms. In the measurements, OH PLIF was e

Introduction: Lyme borreliosis (LB) is the most common tick transmitted disease in Europe. The diagnosis of LB today is based on the patient´s medical history, clinical presentation and laboratory findings. The laboratory diagnostics are mainly based on antibody detection, but in certain conditions molecular detection by polymerase chain reaction (PCR) may serve as a complement. Aim: The purpose o