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Sexual dysfunction and central obesity in patients with first episode psychosis

BACKGROUND: In recent years the association between sexual dysfunction (SD) and obesity in the general population has drawn major attention. Although sexual dysfunction is common in psychosis, its relationship with weight gain and obesity remains unclear.AIMS: To investigate the association between sexual dysfunction and obesity in a cohort of patients with first episode psychosis.METHOD: Sexual f

Naturalistic studies - Researching the everyday clinical world

During the last decade, a vast amount of research has been produced concerning the efficacy of different pharmacological and psychological treatments in psychiatry for various diagnoses. This movement towards evidence-based practices has aimed at grounding clinical practice in evidence derived from research, to optimize outcomes. Such developments should translate into the successful management of

Efficacy of asenapine in manic episodes with depressive symptoms: A review of post-hoc analyses

Background: Manic episodes with depressive symptoms represent a severe presentation of bipolar disorder. The effi-cacy of drugs shown useful for pure mania is largely unproven in the subset of patients with depressive symptoms. We reviewed different post-hoc analyses evaluating asenapine's effects in patients experiencing depressive symptoms during manic episodes. Methods: Different post-hoc analy

The impact study - Motivating a change in health behaviour

IMPaCT is a five-year project funded by the Department of Health, UK. Running in the UK and now Sweden, the IMPACT Project aims to target the poor physical health and excessive substance use seen in people with SMI. There is evidence that behavioural interventions may be associated with an improvement in physical health and substance use in this population. IMPaCT is a randomised controlled trial

The inadequacy of ADHD: a philosophical contribution

Attention Deficit Hyperactivity Disorder (ADHD) is a widely spread diagnosis.The dominant paradigm of ADHD is biomedical where ADHD isdefined as a brain disorder. At the same time, the legitimacy of thediagnosis is being questioned since it is unclear whether or not ADHDcan be deemed a medical disorder in itself. The aim of this article is tocritically assess the merits of understanding the diagnoAttention Deficit Hyperactivity Disorder (ADHD) is a widely spread diagnosis.The dominant paradigm of ADHD is biomedical where ADHD isdefined as a brain disorder. At the same time, the legitimacy of thediagnosis is being questioned since it is unclear whether or not ADHDcan be deemed a medical disorder in itself. The aim of this article is tocritically assess the merits of understanding the diagno

Cats parallel great apes and corvids in motor self-regulation, but size matters

We tested domestic cats in the cylinder task, and found that they perform better ifthe cylinder is larger. We also found that their highest performance parallels that ofgreat apes and corvids, which are known as the best performing animals on this task.The cylinder task is used to test animals’ motor self-regulation. Recently a large-scalestudy tested 36 species on the task and found that absolute

Cylinder size affects cat performance in the motor self-regulation task

We tested domestic cats in the so-called cylinder task, and found that they perform better if the cylinder is larger. We also found that their highest performance parallels that of great apes and corvids, which are known as the best performing animals on this task. The cylinder task is used to test animals’ motor self-regulation: the inhibition of unproductive, but prepotent, movements in favour o

Techno-economic evaluation of biogas upgrading using ionic liquids in comparison with industrially used technology in Scandinavian anaerobic digestion plants

The process of biogas upgrading with ionic liquids, i.e. pure 1-butyl-3-methylimidazolium bis(trifluoro-methylsulfonyl)imide ([bmim][Tf2N]), aqueous choline chloride/urea (ChCl/Urea), and aqueous 1-allyl-3-methyl imidazole formate ([Amim][HCOO]), was simulated in Aspen Plus and compared with the conventional water scrubbing upgrading technique. The comparisons of the performances on the amount of

Do humans really prefer semi-open natural landscapes? A cross-cultural reappraisal

There is an assumption in current landscape preference theory of universal consensus in human preferences for moderate to high openness in a natural landscape. This premise is largely based on empirical studies of urban Western populations. Here we examine for the first time landscape preference across a number of geographically, ecologically and culturally diverse indigenous populations. Included

Pronouns in affinal avoidance registers : Evidence from the Aslian languages (Austroasiatic, Malay Peninsula)

Affinal avoidance registers are strategies of restrained linguistic conduct in relation to one’s in-laws. Current theories are primarily concerned with two types of strategies: (1) taboos on uttering the proper names of affines, and (2) substitution of everyday words with dedicated parallel lexicon in the presence of affines (so-called “mother-in-law languages”). However, the role of pronouns has

Being disconnected from life : meanings of existential loneliness as narrated by frail older people

Objectives: This study illuminated the meanings of existential loneliness (EL) as narrated by frail older people. Method: Data were collected through individual narrative interviews with 23 people 76–101 years old receiving long-term care and services. A phenomenological hermeneutical analysis was performed, including a naïve reading and two structural analyses as a basis for a comprehensive under

Population-based incidence rate of inpatient and outpatient surgical procedures in a high-income country

Background: The WHO and the World Bank ask countries to report the national volume of surgery. This report describes these data for Sweden, a high-income country. Methods: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The

Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib

Objectives: Translocations involving the fibroblast growth factor receptor 1 (FGFR1) gene are associated with the 8p11 myeloproliferative syndrome (EMS), a rare neoplasm that following a usually short chronic phase progresses into acute myeloid or lymphoid leukemia. The treatment commonly involves chemotherapy and, if possible, allogeneic stem cell transplantation which is the only therapeutic opt

Investigating lexical competition and the cost of phonemic restoration

Due to phonemic restoration, listeners can reliably perceive words when a phoneme is replaced with noise. The cost associated with this process was investigated along with the effect of lexical uniqueness on phonemic restoration, using data from a lexical decision experiment where noise replaced phonemes that were either uniqueness points (the phoneme at which a word deviates from all nonrelated w